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The extrinsic glands of the digestive system

include the major salivary glands, the pancreas,
and the liver, all of which are located outside the
wall of the digestive tract.

The major salivary glands consist of three
pair of glands: the parotid, submandibular glands
and sublingual glands.
Interlobula
r septum

parenchyma

Specimen NO.43 Submandibular gland : mixed gland HE

serous demilune ②

Specimen NO.43 Submandibular gland ①Mixed acinus ②Serous acinus

Intercalated duct

Specimen NO.43 Submandibular gland ①mucous acinus ②Serous acinus
① ②

Specimen NO.43 Submandibular gland ①Secretory duct ②Serous acinus
Small
vein

Intralobular
duct

Specimen NO.43 Submandibular gland
The pancreas can be divided into two portion:
exocrine portion and endocrine portion. The
exocrine portion is a serous, compound tubloacinar
gland. The endocrine portion is called pancreatic
islet( islet of Langerhans).

Specimen NO.46 Pancreas ①pancreatic islet ②exocrine portion HE
Specimen NO.46 Pancreas centroacinar cells( )

Specimen NO.46 Pancreas ①Pancreatic islet ②Exocrine portion

A cell of pancreatic islet
①Nucleus ②Secretory granule The cells secrete glucagon. (TEM)

①Nucleus ②Secretory granule
B-cell of pancreatic islet
The B cells secrete insulin. (TEM)
The liver is the biggest gland in the body. It
can be divided into two main parts: hepatic lobule
and portal area.

The hepatic lobule includes five components:
central vein, hepatic plate(cord), hepatic sinusoid,
perisinusoidal space and bile canaliculi.
Hepatic
lobule

Portal
areas

Specimen NO.47 Liver of pig HE stain
Hepatic
sinusoid
Hepatic
cord

Central vein

Specimen NO.47 Liver of pig showing hepatic lobule HE s
Hepatocyte
Hepatocyte
Fat- storing cell
② ③

Specimen NO.47 Liver of pig showing Portal area of liver
①Interlobular artery ②Interlobular vein ③ Interlobular bile duct
Central vein

Central
vein

Specimen NO.48 Liver of human HE stain
Hepatic
macrophage

Hepatic
macrophage

Specimen NO.49 Liver of mouse (trypan blue injected preparation)
Hepatic macrophage in hepatic sinusoid (SEM)
bile
canaliculus

Central
vein

Specimen NO.50 Liver of mouse showing bile canaliculus. silver stain
bile canaliculus

Specimen NO.50 Liver of mouse showing bile canaliculus silver stain
Three layers : mucous
plica membrane, muscularis and
serosa.

Specimen NO.51 gall bladder HE
Simple
columnar
epithelium

Specimen NO.51
Gall bladder
HE Stain
QUESTIONS
1 . Describe the general structure of salivary gland.
2 . What structure features do the acini of pancreas
have?
3 . How many tapes of cells does the pancreas islet
include?
4 . Describe the structure of hepatic lobule.