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CRANIAL NERVE NUCLEI - LECTURE A

NBIO 401 – Wednesday, October 3, 2012

Objective for the first two cranial nerve lectures, those about cranial nerve nuclei:

-Be able to summarize the function and location of each cranial nerve nucleus.

Cranial Nerve
Nuclei Introductory
Organization

I

Optic Nerve

II

III

V
VI
VII
VIII
IX
X
XII

I ONLY III .XII Optic Nerve II III V VI VII VIII IX X XII .

V Optic Nerve II III V VI VII VIII IX X XII .I CRANIAL NERVE NUCLEI A = III .

I Optic Nerve II III CRANIAL NERVE NUCLEI B = VI .XII V VI VII VIII IX X XII .

Sensory GSA and SSA Mesencephalic Trigeminal V (jaw muscle spindles) Main Sensory Trigeminal V (face touch & proprioception) Vestibular/ Cochlear VIII (vestibular & auditory signals from the inner ear) GENERAL SOMATIC CRANIAL NERVE NUCLEI Motor GSE Oculomotor III (eye muscles) Trochlear IV (eye muscles) Abducens VI (eye muscles) Spinal Trigeminal V (face pain) Hypoglossal XII (tongue muscles) .

IX. X (sensory information for autonomic control) Dorsal motor n. of X (parasympathetic drive to smooth muscles & organs in chest and abdomen) .Sensory GVA GENERAL VISCERAL CRANIAL NERVE NUCLEI Motor GVE Edinger-Westphal III (constricts pupil parasympathetic) Superior salivatory VII (drives salivary glands parasympathetic) Inferior salivatory IX (drives salivary glands parasympathetic) Solitarius (caudal half) VII.

X (taste) Facial VII (muscles of facial expression) n. X (muscles of the pharynx & larynx) .Sensory SVA SPECIAL VISCERAL CRANIAL NERVE NUCLEI Motor SVE Motor Trigeminal V (chewing muscles) Solitarius (rostral half) VII. Ambiguus IX. IX.

.sulcus limitans (divides motor nuclei [medial] and sensory nuclei (lateral]).

sulcus limitans (divides motor nuclei [medial] and sensory nuclei (lateral]). .

sulcus limitans .

Motor nuclei locations .

General Somatic Efferents lie close to the midline .

General Visceral Efferents lay laterally to the General Somatic Efferents .

Cranial Nerve Nuclei III-V The Oculomotor (IIIrd) Nucleus .

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Edinger Westphal nucleus (constricts the pupil) Oculomotor nucleus (motoneurons for eye muscles) Oculomotor nerve (to eye muscles & pupil muscles) .

General Somatic Efferents lie close to the midline .

Sensory GSA and SSA Mesencephalic Trigeminal V (jaw muscle spindles) Main Sensory Trigeminal V (face touch & proprioception) Vestibular/ Cochlear VIII (vestibular & auditory signals from the inner ear) GENERAL SOMATIC CRANIAL NERVE NUCLEI Motor GSE Oculomotor III (eye muscles) Trochlear IV (eye muscles) Abducens VI (eye muscles) Spinal Trigeminal V (face pain) Hypoglossal XII (tongue muscles) .

Cranial Nerve Nuclei The Trochlear (IVth) Nucleus .

Trochlear nerve (to eye muscles) Trochlear nucleus (motoneurons for eye muscles) .QuickTime™ an d a GIF decompressor are need ed to see this picture.

General Somatic Efferents lie close to the midline .

Sensory GSA and SSA Mesencephalic Trigeminal V (jaw muscle spindles) Main Sensory Trigeminal V (face touch & proprioception) Vestibular/ Cochlear VIII (vestibular & auditory signals from the inner ear) GENERAL SOMATIC CRANIAL NERVE NUCLEI Motor GSE Oculomotor III (eye muscles) Trochlear IV (eye muscles) Abducens VI (eye muscles) Spinal Trigeminal V (face pain) Hypoglossal XII (tongue muscles) .

Cranial Nerve Nuclei III-V The Trigeminal Nuclei .

the only 1° sensory cell body inside CNS) Sensory Axons signals for conscious touch & muscle spindle/joint receptors (cell body in ganglion outside CNS) Trigeminal nerve (sensory & motor axons of 4 types listed to the right) Motor Axons carrying motor signals to jaw muscles (cell body motor trigeminal nucleus) Sensory Axons signals for pain & temperature (cell body in ganglion outside CNS) .Mesencephalic trigeminal nucleus (1° sensory neurons for muscle spindles & joint receptors in head) To Thalamus Mesencephalic trigeminal tract (axons bringing unconscious signals from muscle spindles & joints in head) Sensory Axons of 1° sensory neuron for unconscious muscle spindle & joint receptors (cell body in mesencephalic trigeminal nucleus .

pain & temperature from head efferent: chewing muscles) . muscle spindle/joint. conscious spindle & joint from head) Main sensory trigeminal nucleus Trigeminal nerve Spinal trigeminal nucleus Spinal trigeminal nucleus (pain & temperature from head) Trigeminal nerve (afferent: touch.Motor trigeminal nucleus Motor trigeminal nucleus (motoneurons for jaw muscles) Main sensory trigeminal nucleus (touch.

Motor Trigeminal Nucleus (right) Main sensory trigeminal nucleus (right) Spinal Trigeminal Nucleus (right) Mesencephalic trigeminal nucleus (left) Mesencephalic trigeminal tract (left) Trigeminal Nerve (right) Spinal trigeminal nucleus (left) Main sensory trigeminal nucleus (left) Trigeminal Nerve (left) Spinal trigeminal nerve (left) (1° axons on way to terminate in spinal trigeminal nucleus) .

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Special Visceral (Branchial) Efferents lie most lateral of the motor nuclei. .

X (taste) Facial VII (muscles of facial expression) n. IX. X (muscles of the pharynx & larynx) .Sensory SVA SPECIAL VISCERAL CRANIAL NERVE NUCLEI Motor SVE Motor Trigeminal V (chewing muscles) Solitarius (rostral half) VII. Ambiguus IX.

ROSTRAL PONS Medial Longitudinal Fasciculus Mesencephalic trigeminal tract & nucleus Superior Cerebellar peduncle Spinothalamic tract Pyramidal Tract Pontine Gray matter Medial lemniscus .

Superior cerebellar peduncle MID PONS Mesencephalic trigeminal tract & nucleus (muscle spindles from chewing muscles & jaw joint receptors) Motor trigeminal nucleus Middle Cerebellar peduncle MLF Trigeminal nerve ( sensory & motor for the head) Spinothalamic tract Pyramidal Tract Pontine Gray matter Medial lemniscus .

Superior cerebellar peduncle (fibers coming out of cerebellum) MID PONS Middle Cerebellar peduncle MLF Main sensory trigeminal Nucleus (face touch) Spinal trigeminal tract & nucleus Motor nucleus of trigeminal (chewing muscle motoneurons) Pyramidal Tract Spinothalamic tract Pontine Gray matter Medial lemniscus .

Facial nerve fibers (looping around abducens nucleus) CAUDAL PONS Abducens Nucleus (eye muscle motoneurons) Vestibular nuclei Spinal trigeminal nucleus & tract MLF Inferior cerebellar peduncle Facial motor nucleus Spinothalamic Tract Middle Cerebellar peduncle Pyramidal Tract Medial lemniscus Pontine Gray matter .

Central canal Gracile Nucleus (touch-leg) Gracile Fasciculus (touch-leg) Cuneate Nucleus (touch-arm) Spinal trigeminal nucleus & tract (head pain & temp) Spinal Accessory Nucleus (motoneurons for trapezius & sternocleidomastoid muscles) Medial Longitudinal Fasciculus (MLF) (vestibular & oculomotor information) Pyramidal Decussation (corticospinal fibers crossing midline) Cuneate Fasciculus (touch-arm) Spinothalamic Tract Pyramids (body pain) (corticospinal fibers) Spinocerebellar Tract (sensory fibers .leg) .Muscle spindle & joint information to cerebellum .

Fini .