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INFORMATION

ABOUT
PREDIABETES

What is Prediabetes
Prediabetes is a condition where your blood glucose or
A1c levels are higher than normal but not high enough for
a diagnosis of diabetes. People with prediabetes are at
higher risk of developing type 2 diabetes and heart
disease. The Centres of Disease Control and Prevention
National Diabetes Statistics Report estimates that 37% of
adults over the age 20 years and more than 50% of those
older than 65 years had prediabetes in 2009-2012 which
translates to about 86 million adults with prediabetes in
United States. The world wide prevalence of prediabetes in
2010 was estimated to be 343 million which is nearly 7.8%
of the world population.

How is prediabetes diagnosed


Prediabetes can be detected with one of the following blood tests Hemoglobin A1c test. This blood test reflects the average blood sugar level
over the past 3 months. This is probably the most reliable test for diabetes. An
A1c of 5.7-6.4% indicates prediabetes.
Fasting blood sugar level. This blood test measures blood glucose level in
people who have not eaten anything for at least 8 hours. Fasting glucose levels
of 100-125 mg/dL indicate prediabetes.
Oral glucose tolerance test (OGTT). This test is done after 8 hours of fasting.
The blood is drawn 2 hours after drinking a sweet liquid. A blood glucose level of
140-1 99 mg/dL is diagnostic of prediabetes.

What are the risk factors for prediabetes?


Family history (parents and siblings) of diabetes.
If you are African American, Hispanic, American Indian, Asian American, Alaska
native.
High blood pressure
Inactive or sedentary lifestyle
History of gestational diabetes
If you gave birth to a baby weighing more than 9 pounds
People with polycystic ovary syndrome
HDL cholesterol below 35 mg/dL or triglyceride level above 250 mg/dL
If you have heart disease or history of stroke
If you have other conditions associated with insulin resistance such as obesity or
have patches on your skin called acanthosis nigricans

How is prediabetes treated

Metformin
is
the
only
medication
that
has
consistently shown to be
beneficial
in
preventing
diabetes. It prevents the liver
from producing more glucose
when you dont need it and
keeps your blood glucose
level in a better range.
Although metformin is not as
good as lifestyle modifications
described above, it reduces
the risk of developing type 2
diabetes by 42%.

Weight Loss Surgery


Surgery for weight loss such as
gastric bypass, gastric sleeve,
lap band will reduce the risk of
developing diabetes or resolve
prediabetes altogether. Studies
have shown that weight loss
surgery
may
completely
normalize the blood sugars in
78% of people with previous
diabetes and in 98% of people
with prediabetes.