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Lecture 1
r

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I want to become a physician
A: T
B: Fr

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I exercise…
A: neverr
B: once per week
C: twice per weekr

D: three times per weekr

E: > than 3 times per weekr

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The longest race I have been in:
A: never been in a racer
B: 5K
C: 10Kr

D: half-marathon (13.1 mi)r

E: full marathon (26.2 mi)r

Clicker I am a member of a UCSD team: A: Yesr B: Nor .

Clicker Would you like to lose weight? A: Yesr B: Nor .

Clicker Would you like to gain weight? A: Yesr B: Nor .

Clicker I took metabolic biochemistry with: A: Hampton (person in front of room)r B: Another Biology Prof C: Another Chemistry Prof D: Can’t remember .

Clicker Lecture 2 r .

Clicker Did you take Metabolic Biochem? A: Yes B: Nor .

Clicker Do you own the textbook? A: Yes B: Nor .

Clicker beta oxdiation A: involves fatty acids B: forms glucose C: is required for Krebs cycle D: forms amino acids .

Clicker Lactic acid is a product of A: aerobic glucose metabolism B: fat metabolism C: anaerobic glucose metabolism D: amino acid metabolism .

Clicker Lecture 3 r .

Clicker Would you like to run/walk a 5K? A: Yes B: Nor .

Clicker Glucose A: always requires O2 for ATP production B: never requires O2 for ATP production C: can be used to make ATP in both cases .

Clicker Muscles store A: glycogen B: triglycerides C: both A and B D: neither A nor B .

Clicker Livers store A: glycogen B: triglycerides C: both A and B D: neither A nor B .

Clicker Adipocytes store A: glycogen B: triglycerides C: both A and B D: neither A nor B .

Clicker Which is true? A: muscles provide glucose to the bloodstream B: liver provides glucose to the bloodstream C: both provide glucose to the bloodstream D: mmm mm mmm (“I don’t know”) .

Clicker Lecture 4 r .

Clicker Lactic acid is produced during fat metabolism: A: True B: Falser .

Clicker Myosin is an enzyme: A: True B: Falser This question was a bit misleading since myosin indeed has the ATP hyrolyzing active site. See lec 8 “points of clarification” r . but restoration of the active site to its state at the start of the catalytic cycle requires its interaction with actin.

Clicker Lower intensity exercise uses a higher proportion of fatty acids as fuel: A: True B: Falser .

Clicker Glucose A: is stored as glycogen in liver and muscle B: is stored as glycogen only in muscle C: is stored as glycogen only in liver .

because I said in lecture 3 (slide 31) 50% is often referred to as a “slow jog” and 70% could be a jog up Torrey Pines Hill. .Clicker 70% VO2max A: might be attained during walking B: might be attained during jogging C: might be attained in a 3 mi race This question is not great.

Clicker Lecture 5 r .

Clicker Do you think you would like to join the 108ers for the Triton 5K? A: Yes B: Nor .

Clicker Myosin and actin both form an active site that hydrolyzes ATP A: True B: Falser .

Clicker Lactate threshold occurs at the point of exhaustion A: True B: Falser .

Clicker Low intensity exercise will help remove lactate built up from intense exercise A: True B: Falser .

Clicker Lecture 6 r .

Clicker Alveolar oxygen p is the same as that in room air A: Tr B: Fr .

Clicker Alveolar number increases with endurance training A: Tr B: Fr .

Clicker CO2 levels of returning blood are as low as atmospheric levels A: Tr B: Fr .

Clicker O2 levels of blood leaving the muscle bed during exercise can be as low as 2 mm Hg A: Tr B: Fr .

Clicker Lecture 7 r .

(Lec 6 slide 17) 38 . but no where near the change in the amount of CO2 that is carried as intensity goes up.Clicker Alveolar PCO2 changes with exercise intensity A: Tr B: Fr They rise slightly at the highest levels of intensity.

Clicker Alveolar PO2 changes with exercise intensity A: Tr B: Fr They dip slightly at the highest levels of intensity. (lec 6 slide 17) 39 . but no where near the change in the amount of O2 that is carried as intensity goes up.

Clicker Blood pH goes up with increased exercise intensity A: Tr B: Fr 40 .

Clicker As blood lactate goes up. pH A: goes downr B: goes upr C: becomes better regulated D: reverses the buildup of lactate 41 .

Clicker Increasing lactate causes changes in blood pH A: Tr B: Fr C: not clear 42 .

Clicker Lecture 8 r .

Clicker Capillary blood flow is increased during exercise A: T B: Fr A 108 member pointed out that flow could mean flow rate. 44 . Blood volume might be a better way to put it. fair enough.

Clicker Total blood volume increases up to 5 fold during exercise A: T r B: Fr 45 .

46 . liver and skin all go down during exercise A: T r B: Fr A 108 member pointed out that flow could mean flow rate.Clicker Blood flow to the brain. fair enough. Blood volume might be a better way to put it. kidney.

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Lecture 10
r
(there were no clicker
questions in lec 9)

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Running speed (over a broad range)

A: does not affect Cal per mile
B: is linearly related to Cal per mile r
C: is exponentially related to Cal per miler
D: is inversely related to Cal per mile r

48

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Walking

A: is always more efficient than running
B: is never more efficient than running
C: is more efficient at slow speed r
D: is less efficient at slow speeds r

49

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Minute volume during exercise

A: increases due to BR changes only
B: increases due to TV changes onlyr
C: is unaffected during exercise r
D: is elevated by both BR and TV increases

50

Clicker Heart rate is A: a good gauge of comparing two peoples using the same amount of O2 B: can be very different between two people using the same amount of O2 r 51 .

Clicker The act of eating and digesting A: gives up energy B: requires energy only due to the physiological processes needed C: requires energy due to CNS responses to eating D: requires energy due to physiological and CNS responses to eating 52 .

Clicker Lecture 11 r .

Clicker Exercise intensity refers to A: amount of energy per unit time B: amount of time the exercise occurredr C: the attitude of the person doing it D: the temperature of the exercise roomr 54 .

Clicker Glucose is released into the blood A: as the 6-phosphate form B: as the 1-phosphate form C: as glycogen particles D: as the neutral molecule C6H12O6 55 .

Clicker The exam was A: evil and mean B: fair but too long C: fair but too short D: unfair Confused. but 90% if people left before 2 hours of the 3 hour test time had elapsed… 56 . Most of you said it was fair but too long.

Clicker Lecture 12 r .

Clicker PGC-1 is a A: contractile protein B: a metabolic enzyme C: a transcriptional repressor D: a transcriptional activator 58 .

Clicker Mitochondrial number A: goes up with endurance training* B: goes down with endurance training C: remains the same with endurance training D: goes up with resistance training *“with” here meaning “as a result of” a little too colloquial I will admit. 59 .

Clicker Mitochondrial enzymes in muscle A: go up with endurance training* B: go down with endurance training C: remain the same with endurance training D: go up with resistance training *“with” here meaning “as a result of” a little too colloquial I will admit. 60 .

.Clicker Glycolytic capacity in muscle A: goes up with endurance training B: goes down with endurance training C: remains the same with endurance training D: goes up with resistance training E: more than one above *“with” here meaning “as a result of” a little 61 too colloquial I will admit.

Clicker Lecture 13 r .

Clicker DOMS stands for A: Don’t over muscle stuff B: Damage On Muscle Structure C: Differential Oncogenic Myotome Staining D: Delayed Onset Muscle Soreness 63 .

Clicker DOMS occurs A: primarily after concentric exercise B: primarily after eccentric exercise C: only after isometric exercise D: after detraining when muscles are not being used 64 .

Clicker Interference is seen A: as a lessening of resistance training effects due to endurance training B: as a lessening of endurance training effects due to resistance training C: both a and b can occur as interference D: only when people are not trained 65 .

Clicker A muscle stem cell is called a A: a myogenic cell B: a myoclonic precursor C: a satellite cell D: a peripheral myocyte 66 .

Clicker Lecture 14 r .

Clicker How many times to you do aerobic exercise? A: once a week B: twice a week C: three times a week D: more than 3 times a week E: never 68 .

Clicker How many times to you do resistance exercise? A: once a week B: twice a week C: three times a week D: more than 3 times a week E: never 69 .

Clicker The heart can change volume from exercise training A: T B: F 70 .

Clicker The blood can change volume from exercise training A: T B: F 71 .

Clicker Lecture 15 r NO CLICKAGE .

Clicker Lecture 16 r .

Clicker Get those gol durn clickers out! 74 .

Clicker Anandamide could be called A: Brain-made heroin B: Brain-made weed C: Brain-made alcohol D: The active ingredient in cannabis 75 .

Clicker Mice lacking the CB1 receptor A: run less than wild-type mice B: run more than wild-type mice C: run more than wild-type mice D: run the same but have lost their zest for life 76 .

Clicker Endorphins could be called A: Brain-made heroin B: Brain-made weed C: Brain-made alcohol D: The active ingredient in cannabis 77 .

Clicker Since this class started A: I exercise more B: I exercise less C: I stopped exercising D: I started exercising E: I exercise same as before 78 .

Clicker Lecture 17 .

Clicker Type I fibers are innervated by A: the thinnest neural fibers B: intermediate neural fibers C: the thickest neural fibers D: a combination of these fibers 80 .

Clicker Type IIx fibers are innervated by A: the thinnest neural fibers B: intermediate neural fibers C: the thickest neural fibers D: a combination of these fibers 81 .

Clicker Which mechanism is most important for heat dissipation A: conduction B: evaporation C: convection D: radiation 82 .

Clicker Which mechanism is most important in wind chill effects A: conduction B: evaporation C: convection D: radiation 83 .

a submaximal work load A: requires the same O2 as at sea level B: requires more O2 than at sea level C: requires less O2 than at sea level D: would be anaerobic due to low O2 84 .Clicker At high altitude.