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DEFINITION

Leukemia is a cancer of blood. It is a group of


malignant disorders affecting the blood and tissue
forming the blood such as:
Bone marrow
Lymph system
Spleen
Leukemic cells replace white blood cells and
makes the body very weaker and vulnerable to
any infection

Leukemia may affect females and males of all


age groups
TYPES OF LEUKEMIA

Acute
Acute Lymphoblastic Leukemia(ALL)
Acute Myeloid Leukemia(AML)

Chronic
Chronic Myeloid Leukemia(CML)
Chronic Lymphocytic Leukemia(CLL)
DIFFERENCES BETWEEN ACUTE
AND CHRONIC LEUKEMIA
ACUTE CHRONIC
Progress rapidly Progress slowly
Severely ill Can be asymptomatic
Heals without complication Complication arises
Common in younger age Common in older age groups
groups
Need immediate treatment Treatment can be delayed
It is prominent It is mild
Prognosis is predictable Prognosis is unpredictable
Normal growth factor levels Lower growth factor levels
Normal level of inflammatory Increased level of pro
cytokines inflammatory cytokines
PATHOPHYSIOLOGY
ETIOLOGY
Heredity
Environmental factors
Infections
Consumption of alcohol
and drugs
Smoking
Radiation exposure
Association with diseases
of immunity
DIAGNOSIS
Blood test
Bone marrow test
Biopsy
Physical test
Blood cell examination
Cytogenetic
TREATMENTS
Chemotherapy
Biological Therapy
Targeted Therapy
Radiation Therapy
Stem Cell Therapy
Watchful Waiting
Bone Marrow Transplantation
GRAPH REPRESENTING
PERCENTAGE OF LEUKEMIA
PATIENTS BASED ON AGE