Desmoplastic trichoepithelioma

Deba P Sarma, MD Omaha

M 73, right cheek

Desmoplastic trichoepithelioma shows aggregates of basaloid cells in the dermis resembling a syringoma; however, they contain keratin instead of eccrine secretion. Also present is the characteristic markedly
fibrous stroma. Pleomorphism, palisading, or peripheral clefting are not seen. Features favoring desmoplastic trichoepithelioma include a rim of compact collagen around groups of epithelial cells, calcification of cornified cells within cysts, absence of necrotic neoplastic cells, and only rare mitotic figures.

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