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HUMAN BLOOD

R.B.C
 Red blood cells contain a
special protein called
hemoglobin, which
contains iron and carries
the oxygen to the body
 Hemoglobin also makes
red blood cells red.
 We have so many red cells
that our blood itself appears
red, even though it contains
more than red blood cells.
Inheritance of
Blood Types
Discovery of Blood Typing

Dr. Karl Landsteiner • First to discover blood types


(1900)

• Observed blood transfusions:


the transfer of blood from one
to another.
• Noticed that the blood of the
donor would clump/clot with that
of the patient (Agglutination)
The Four Classic Blood Types

____
A ____
B ____
AB ____
O
The difference in blood types is caused by different
proteins found of the surface of the red blood cells
known as Antigen A and Antigen B.
The Four Classic Blood Types

Antigen
_________:substance that can trigger the production of
antibodies.
Antibodies
_____________:proteins produced by the immune system
that destroy foreign substances (such as antigens).
Blood Types

Blood Antigen(s) on Antibodies Can donate Can receive Genotypes:


Types: RBC produced blood to: blood from:

A Antigen A Anti B
A AB A O IAIA IAi
B Antigen B Anti A B AB B O IBIB IBi
AB Antigens A&B NONE AB ALL IAIB
O Neither Anti A&B ALL O ii
Rh Factor in Blood

•The Rh factor is another protein factor on the Red


Blood Cells

•The term Rh comes from the type of monkeys used


to test for this factor originally, Rhesus Monkeys
Rh Factor Statistics

•85% of people have Rh present on their red blood


Rh+ and they can
cells. Their blood is referred to as _____
+ and - blood.
receive ___________

•15% of people DO NOT have Rh present on their red


Rh- and
blood cells. Their blood is referred to as ______
only -
they can receive ____________.

•Universal blood donor (used by all)_____.


O-
•Universal blood recipient (can receive all types)____.
AB+
Rh Factor and Pregnancy

Rh (-) Mother X Rh(+) Father

1st Rh (+) Baby 2nd Rh (+) Baby


Rh Factor and Pregnancy
World Map of the A Allele
World Map of the B Allele
World Map of the O Allele Blood Type