A WIRELESS- IMPLANTABLE MICRO SYSTEM FOR CONTINUES BLOOD GLUCOSE MONITORING

ANOOP P Roll No:07 Reg. No:CTAHEEC013

ABSTRACT
‡ Remotely powered implantable micro system ‡ Consists of a micro fabricated glucose biosensor ip-chip bonded to a transponder chip ‡ Transponder chip measures the output signal of the glucose biosensor and transmits to the external reader ‡ Chip can measure the sensor output current ranging from 1 nA to 1 A

LITERATURE SURVEY
1. NON-CONTINOUS BLOOD GLUCOSE MONITORING

‡ Consist of a blood glucose meters ‡ small drop of blood is needed to place on test strip

LITERATURE SURVEY
2. Continues wired blood glucose monitoring ‡ Used conventional electrochemical glucose sensors ‡ Large sizes ‡ Wired

DESIGN

DESIGN
‡ Microfabricating the glucose sensor ‡ Inegrating all the interfacing circuits into a integral chip(TRANSPONDER CHIP) ‡ Attaching the microfabricated glucose sensor to the transponder chip using flip chip bonding

SYSTEM OVERVIEW AND FUNCTIONING

SYSTEM OVERVIEW AND FUNCTIONING
‡ Monitoring system consisting of an implantable microsystem and an external reader. ‡ Microsystem measures the blood glucose concentration and transmits the measured data to the external reader

GLUCOSE SENSOR
‡ Amperometric electrochemical biosensor ‡ Consists of three electrodes: 1)a working electrode(WE) 2)a reference electrode(RE) 3)a counter electrode(CE)

ELECTRODES
1. WORKING ELECTRODE

‡ Act as a surface on which the electrochemical reaction takes place between the glucose and an enzymatic layer ‡ It catalyzes the oxidation of glucose to gluconic acid

ELECTRODES
2. REFERENCE ELECTRODE ‡ The reference electrode is used to measure the solution (blood or interstitial uid) potential

ELECTRODES
3. COUNTER ELECTRODE ‡ An inert conductor (gold) that supplies the current required for the electrochemical reaction

TRANSPONDER CHIP
1. RF FRONT-END BLOCK

TRANSPONDER CHIP
2. DATA-ACQUISITION

EXTERNAL READER

ADVANTAGES
‡ Small size of the implant ‡ No need of oxygen ‡ Use of passive telemetry link

CONCLUSION
‡ Miniaturization procedure for a wirelessimplantable microsystem for continuous blood glucose monitoring ‡ Low cost procedure ‡ Microsystem implanted just underneath the skin

REFERENCES
‡ IEEE Trans.Biomed. Eng., vol. 35, no. 7, pp. 526 532, Jul. 1988. ‡ IEEE Trans. Biomed.Eng., vol. 41, no. 10, pp. 937 942, Oct. 1994. ‡ Biosensors Bioelectron., vol. 10, pp. 485 494, 1995

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