Professional Documents
Culture Documents
PRINCIPLES
Strain selection
Laboratory process development
Pilot Scale up
Industrial Scale up
Fermentation Media Preperation
Downstream process development
Product packaging techniques
Other Commercial consideration
Waste Disposal
May 21, 2019 Stages in an Industrial Bioprocess
May 21, 2019 Stages in an Industrial Bioprocess
An Ideal STRAIN
Genetic Stability
Efficient production of target product
Limited need for vitamins and growth factors
Utilization of wide range of low cost substrates
Safety, GRAS
Ready harvesting
Limited by products production
Easy genetic amenability
How?
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Screening of nature circumstances
Genetic engineering
Mutations
Cell biology techniques
May 21, 2019 Stages in an Industrial Bioprocess
International Culture Collections
Primary Screening
Secondary Screening
Via chemical
or physical,
and biological
means