PATOLOGIA FICATULUI

HEPATIC PATHOLOGY

a c Morfologia normal a ficatului: a ± aspect macroscopic. b ± aspect pe sec iune.structura microscopic a lobulului hepatic portal (zonele 1. c . 2 i 3) b .

Viral .Pattern of Liver Damage ‡ ‡ ‡ ‡ Zonal ± Toxin/Hypoxia Bridging ± Viral severe Interface ± Immune Apoptotic .

Steatoza ficatului .

Necroz masiv a ficatului (distrofie toxic ) .

Chronic .Acute .Hepatitis .

Hepatit alcoolic . steatoz i corpusculi Mallory p .

Alcoholic Liver Damage .

infiltra ia limfoid a tractelor portale (necroz periportal parcelar )o . distorfie hidropic i corpusculi Councilman n.Hepatit viral .

n Hepatocite ³de sticl mat ´ cu citoplasma omogenizat (acumul ri masive de HBsAg) Ground glass hepatocytes with homogenous cytoplasm (massive accumulation of HBsAg) n Fragmente rotunde eozinofile de hepatocite apoptozice ± corpusculi Councilman n Rounded eosinophil fragments of apoptotic hepatocyte ± Councilman bodies .

(a. d) . b) i micronodular (c.a c d b Ciroz macro.

aspecte microscopice .Ciroz hepatic .

Dilatarea varicoas a venelor esofagiene o i peretelui abdominal anterior p p .

Jaundice .

Splenomegalie .

Calculi i staz biliar în ficat .

Carcinom hepatic nodular .

structuri trabeculare .Carcinom hepatic hepatocelular.

Metastaze de carcinom în ficat .

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