Professional Documents
Culture Documents
1. Kelenjar endokrina
- sel-sel, tisu-tisu dan organ-organ yang
merembeskan hormon ke dalam cecair badan
secara langsung tanpa duktus.
2. Kelenjar eksokrina
- bhg organ yg merembeskan penghasilan ke
dlm dan permukaan badan melalui duktus.
Nama kelenjar Lokasi
Timus Di mediastinum
Pineal Gland
-Role Melatonin
--Mammals : Regulate
reproductive activity in
response to environmental
light cycles
e.g. Some mammals mate in
summer (lot of light), while
others mate in winter (low
light).
The Endocrine Glands & their Hormones
Thyroid Gland
-Produces 3 main hormones
-Triiodothyronine (T3)
-Thyroxine (T4)
Regulate body metabolism and are
important in bone growth and maturation
of the brain
-Congenital lack of thyroid hormones:
Cretinism.
-Calcitonin
Acts by reducing calcium levels
The Endocrine Glands & their Hormones
Parathyroid Gland
-Parathyroid Hormone
(antagonize Calcitonin)
Thymus Gland
-Thymosin :
Stimulates the production of Lymphocytes
-Thymostatin :
Inhibits the production of Lymphocytes
Heart
-Granular cells in the heart muscle
secrete Atrial Natriuretic Factor (ANF)
Gastrointestinal Hormones
-The mucosa of the GI tract secretes a
dozen PEPTIDE hormones
3 most important:
1. Secretin :
Secreted in the small intestine Stimulates the
secretion of pancreatic bicarbonate and has
other functions on digestion
2. Gastrin:
Secreted in the walls of stomach Stimulate
hydrochloric acid secretion stimulate
pancreatic enzyme secretion
3. Cholecystokinin :
Secreted in the small intestine Stimulate gall
bladder contraction Stimulate pancreatic
enzyme secretion
The Endocrine Glands & their Hormones
Pancreas
Endocrine cells in the pancreas secrete
2 major types of hormones
1. Insulin :
Secreted in response to increase in blood
glucose levels ; So insulin LOWERS
glucose levels by INCREASING glucose
UPTAKE in cells where it is stored as
glycogen.
2. Glucagon :
Increases blood glucose levels by
stimulating the conversion of glycogen to
glucose in the liver.
A parte : Insulin & Diabetes
Adrenal Glands
Adrenal Cortex :
3 categories of steroid hormones
1. Mineralocorticoids
2. Glucocorticoids
3. Sex Steroids
Adrenal Medulla
1. Adrenaline
2. Noradrenaline
The Endocrine Glands & their Hormones
Adrenal Cortex
Androgen Influence sexual differentiation
and bodily changes during puberty
Estrogen
Stress Hormone, converts stored
proteins to carbohydrate during
Stress. Anti inflammatory and
Immunosuppressive functions.
If there is a sodium deprivation,
Aldosterone is secreted and acts
to increase reabsorption of
sodium ions (NA+) in the kidneys
salivary glands, and sweat glands.
The Endocrine Glands & their Hormones
Adrenal Medulla
Gonads ; Testes
The male gonads : produces Androgens
Gonads ; Ovaries
2 major classes of hormones
ESTROGENS
PROGESTINS
Gonads ; Ovaries
PROGESTIN : Progesterone
Placenta
-Hormones secreted by the fertilized egg
(Used in pregnancy tests)
Also called
the HYPOPHYSIS
The Pituitary Gland & its Hormone
-HYPOTHALAMIC-PITUITARY
connection
The Pituitary Gland & its Hormone
ANATOMY
ADENOhypophysis
-3 parts
NEUROhypophysis
--> Posterior Lobe
-pars nervosa
(“neural” cells)
direct extension
of the
hypothalamus
The Pituitary Gland & its Hormone
PVN SON
-Neuroscretory Cells
-Paraventricular nucleus (PVN)
-Supraoptic nucleus (SON)
-Hormones secreted
AXONS
-OXYTOCIN
-VASOPRESSIN
Attaches the
hypothalamus to the
pituitary. Also called
the Infundibulum
Neurohypophysis
The Pituitary Gland & its Hormone
PVN SON
AXONS -OXYTOCIN :
2 main functions
Attaches the
hypothalamus to the --> promotes uterine contractions
pituitary. Also called --> stimulates milk ejection from
the Infundibulum mammary glands during
lactation
Neurohypophysis
The Pituitary Gland & its Hormone
PVN SON
-VASOPRESIN :
--> Neurophysins
Neurohypophysis
The Pituitary Gland & its Hormone
ADENOHYPOPHYSIS (ANTERIOR)
Adenohypophysis
The Pituitary Gland & its Hormone
Adenohypophysis : 6 hormones
Adenohypophysis : 6 hormones
2. Adrenocorticotropic Hormone
ACTH
Adenohypophysis
The Pituitary Gland & its Hormone
Adenohypophysis : 6 hormones
Adenohypophysis
The Pituitary Gland & its Hormone
Adenohypophysis : 6 hormones
3 last hormones=
….gonadotropic hormones
Adenohypophysis : 6 hormones
3 last hormones=
….gonadotropic hormones
Adenohypophysis : 6 hormones
3 last hormones=
….gonadotropic hormones
6. Prolactin (PRL)
AXONS
Role : Initiates milk synthesis in
mammary glands
Attaches the
hypothalamus to the Other functions related to
pituitary. Also called growth & parental behavior
the Infundibulum
Interaction with serotonin also
(important in depression)
Adenohypophysis
The Pituitary Gland & its Hormone
--> beta-endorphin
Adenohypophysis
The Pituitary Gland & its Hormone
Attaches the
hypothalamus to the
pituitary. Also called
the Infundibulum
TERIMA KASIH