Writing Problem and Hypothesis

Statements for Science Research(10)

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Setting of work proposal :
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Work problem :
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Quantitative specification of problem :

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Importance of problem :
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Project need : ,
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Work objective : ?
Methodology to achieve objective
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Anticipated results :
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Contribution to field :
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()
Given its extensive use for many centuries, Chinese
herbal medicine has received increasing emphasis among clinical
researchers in Taiwan, as evidenced by the analysis of its efficacy by
several analytical methods. However, extracting
traditional Chinese medicine requires a large quantity of medicinal
components and cooking for extended periods, making it less efficient
to produce than Western medicine. (NOTE : Add 2-4 sentences that
describe characteristics of the problem or statistics that reflect its
severity) For instance, preparing traditional
Chinese medicine for intake requires at least 2 hours in arrangement,
making it an inefficient procedure. The inability to
adopt scientific methods to extract the valid compounds of traditional
Chinese medicine makes it unfeasible for modern clinical practice
owing to its inefficiency. Therefore, an extraction
method must be developed for the valid compounds of traditional
Chinese medicine through animal-based clinical trials for eventual use
in humans.
()
An extraction method can be developed for the valid
compounds of traditional Chinese medicine through animal-based
clinical trials for eventual use in humans. To do so,
components of traditional Chinese medicine such as Chinese rhubarb
can be collected in a container and then extracted by supercritical fluids.
Following extraction, the traditional Chinese medicine can then be
analyzed quantitatively and qualitatively by LC-Mass. Next, exactly
what chemical elements are found in traditional Chinese medicine can
then be confirmed through analysis. Additionally, the major chemical
components can be adopted in animal or cell-based experiments.
As anticipated, the proposed extraction method can reduce
nearly half the time required by conventional approaches in extracting
the valid compounds of Chinese medicine, making it an economically
viable alternative. Moreover, the proposed method can
significantly reduce the time required to prepare Chinese medicine for
consumption, as well as ensure safe and modern applications for
clinical medicine. (NOTE : Add 2-4 more sentences that describe
more thoroughly how the proposed method contributes to a particular
field or sector)
()
As is well known, silver nanoparticles have an affinity with a
proteins thiol and amino group. Surface plasma resonance (SPR), a biosensor,
can detect proteins because silver nanoparticles have a coating on SPR,
necessitating the ability to use SPR sensitively and accurately SPR to detect
proteins. For instance, a protein containing amyloid -derived diffusible ligands
(ADDLs) causes Alzheimers disease. Although localized SPR
(LSPR) is more sensitive and accurate than the conventionally adopted SPR,
LSPR has many nanostructures, explaining why sensitivity and accuracy are of
priority concern. Moreover, the conventionally adopted SPR is more expensive
than LSPR. (NOTE : Add 2-4 sentences that describe characteristics of the
problem or statistics that reflect its severity) While the
sensitivity of SPR is 100pM, the LSPR must have a higher sensitivity and
accuracy, hopefully below 1pM. Developing a biosensor
without a LSPR would lead to a more expensive detector. Moreover, the
inability to increase sensitivity and accuracy of the biosensor makes it
impossible to detect the bio molecular structure in early stages, subsequently
creating greater problems such an increased societal burden in caring for
such patients. Therefore, a sensitive and accurate biosensor
must be designed that can identify special proteins efficiently, as well as detect
certain diseases in their early stages.
()
A sensitive and accurate biosensor can be designed that
can identify special proteins efficiently, as well as detect certain
diseases in their early stages. For instance, identifying the protein
ADDLs early can be used to diagnose Alzheimers disease in its early
stages so that therapeutic treatment can be administered.
To do so, nanoparticles can be developed in a glass chamber,
followed by design of a LSPR biosensor. The bio molecular structure
can then be detected using LSPR, enabling us to identify the disease.
As anticipated, the proposed analytical method for
detecting bio molecular structures can detect solution consistency
below 1pM with a high degree of accuracy. Moreover, the
proposed LSPR biosensor can provide a highly sensitive and accurate
means of detecting the bio molecular structure. The ability to identify
the disease in its early stages can lead to earlier treatment and
recovery. For instance, Alzheimers disease can be diagnosed early
because LSPR can detect ADDLs with a high degree of sensitivity,
ultimately increasing the survival rate of patients. (NOTE : Add 2
sentences that describe more thoroughly how the proposed method
contributes to a particular field or sector)
Further details can be found at
http://www.chineseowl.idv.tw