SISTEM INTEGUMEN

ULFAH DIAN INDRAYANI Laboratorium Histologi FK UNISSULA April 2011

FUNGSI KULIT
1. 2. 3. 4. 5. 6. 7.

Proteksi Water barrier mencegah penguapan berlebihan Mengatur suhu badan Pertahanan non spesific Ekskresi garam Sintesis vitamin D Organ sensoris

STRUKTUR UMUM KULIT

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Kulit tebal vs kulit tipis

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Lapisan epidermis

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Dermis
Dermis

Stratum

papilaris

Stratum retikularis Mekanore septor: Badan pacini, badan ruffini

Kolagen tipe III, elastic fiber, Fibroblas, makrofag, sel plasma, sel mast

Mekanoresep tor : Badan meisner, badan krause

Kolagen tipe I, elastic fiber, fibroblas, limfosit, makrofag, sel lemak

Kelj keringat, kelj sebasea, folikel rambut

Figure 11-12 Blood supply to the skin

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Figure 11-13 Sensory receptors of the skin

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Rambut
y Struktur berkeratin yang sangat dimodifikasi y Dihasilkan oleh folikel rambut

pertumbuhan ke bawah epitel

permukaan y Pertumbuhan rambut terjadi di bagian akhir folikel yang melebar bulbus rambut epitel yang aktif membelah mengelilingi papil jaringan vaskuler (papil dermis) y Muskulus arektor pili melekat pada selubung folikel dan tertanam di papil dermis y Muskulus arektor pili disarafi oleh saraf simpatis dingin, takut berdiri

Folikel rambut
y Struktur tubular yang terdiri atas lima lapis konsentris sel

epitel:
y pele

Kelenjar Sebacea
y Setiap folikel rambut memiliki satu atau lebih kelenjar

sebasea mensekresi sebum bahan tahan air dan pelembab rambut & kulit kepala y Pada daerah peralihan kulit-saluran tubuh (bibir, palpebra) kelenjar sebasea terdapat bebas dari folikel rambut dan bersekresi langsung pada permukaan kulit

Kelenjar keringat
y Mensekresi cairan encer pada permukaan kulit melalui proses

merokrin y Kelenjar di ketiak dan genital apokrin, sekret kental dicurahkan ke dalam folikel rambut

Figure 11-14 Migratory pathways of stem cell keratinocytes

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Folikel rambut

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Kelenjar kulit

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Figure 14-15 Structure of the thumbnail.

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Figure 11-15 Structure of the hair

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Figure 11-16 Sebaceous gland: Holocrine secretion

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Figure 11-17 Eccrine sweat glands: Merocrine secretion

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Figure 11-18 Apocrine sweat glands: Merocrine secretion

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Figure 11-19 Cystic fibrosis and sweat glands

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Figure 11-20 Structure and formation of the fingernail

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