REFERAT TB

RADIOLOGI

Epidemiologi
• Mycobacterium tuberculosis telah menginfeksi sepertiga penduduk dunia. • TBC menjadi penyebab kematian utama, hingga dua juta orang pada tahun 1990. Hal tersebut disebabkan oleh : (1) program pengendalian penyakit yang tidak adekuat. (2) Multiple Drug Resistance (MDR). (3) co-infection dengan HIV. (4) Peningkatan jumlah penduduk, terutama dewasa muda yang merupakan kelompok umur dengan mortalitas tertinggi dari tuberkulosis.

• Berdasarkan Global Tuberculosis Control Tahun 2009 (data tahun 2007) prevalensi semua tipe TB sebesar 244 per 100.000 penduduk atau sekitar 565.614 kasus semua tipe TB • insidensi semua tipe TB sebesar 228 per 100.000 penduduk atau sekitar 528.063 kasus semua tipe TB • Insidensi kasus baru TB BTA Positif sebesar 102 per 100.000 penduduk atau sekitar 236.029 kasus baru TB Paru BTA Positif • kematian TB 39 per 100.000 penduduk atau 250 orang per hari.

Definisi
• Tuberkulosis paru (TB) adalah suatu penyakit menular yang disebabkan oleh basil Mycobacterium tuberculosis

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Klasifikasi Organ Pengobatan Paru Ekstra paru Ringan BTA + BTA - Berat .

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PATOGENESIS Primer Post Primer .

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Diagnosis Klinis Bakteriologis Radiologis .

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BMJ Case Reports 2009.2009.1823 ©2009 by BMJ Publishing Group Ltd . Bansal M et al.04.2009:bcr.Chest x ray (posterior–anterior) view showing significant findings.

Leung A N Radiology 1999.210:307-322 ©1999 by Radiological Society of North America .Sputum culture-positive TB in an 82-year-old Asian woman.

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210:307-322 ©1999 by Radiological Society of North America .Atypical distribution of postprimary TB in a 62-year-old man. Leung A N Radiology 1999.

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. QuickTime™ an d a decompressor are need ed to see this picture . The magnified view shows the irregular bronchovascular structures (arrow heads).Chronic Bronchitis.

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210:307-322 ©1999 by Radiological Society of North America . Leung A N Radiology 1999.Postprimary pattern of TB in a 54-year-old Hispanic man.

©1999 by Radiological Society of North America Leung A N Radiology 1999.210:307-322 .Chest radiograph obtained in a 3-year-old Hispanic boy shows mediastinal and right hilar lymphadenopathy.

210:307-322 . ©1999 by Radiological Society of North America Leung A N Radiology 1999.Chest radiograph obtained in a 7-month-old Hispanic boy shows right paratracheal lymphadenopathy (straight arrow) with multilobar consolidation predominating in the right lung.

210:307-322 . ©1999 by Radiological Society of North America Leung A N Radiology 1999.Chest radiograph obtained in a 4-year-old boy shows right hilar lymphadenopathy (arrow) associated with right upper lobe consolidation.

©1999 by Radiological Society of North America Leung A N Radiology 1999.210:307-322 .Chest radiograph obtained in a 19-year-old woman shows a large right-sided pleural effusion (curved arrows) associated with right hilar lymphadenopathy (straight arrows).

©1999 by Radiological Society of North America Leung A N Radiology 1999.Atypical distribution of postprimary TB in a 62-year-old man.210:307-322 .

210:307-322 . ©1999 by Radiological Society of North America Leung A N Radiology 1999.Close-up radiographic view of the upper lung zones in a 56-year-old Hispanic man shows illdefined parenchymal opacities (white arrows) associated with nodular and linear components in the periphery of the bilateral upper lobes.

©1999 by Radiological Society of North America Leung A N Radiology 1999.210:307-322 .Postprimary pattern of TB in a 54-year-old Hispanic man.

©1999 by Radiological Society of North America Leung A N Radiology 1999.Postprimary pattern of TB in a 54-year-old Hispanic man.210:307-322 .

Penatalaksanaan • • • • Menyembuhkan penderita Mencegah kekambuhan Menurunkan tingkat penularan Mencegah kematian .

OAT • • • • Kategori 1 (2RHZE/4R3H3) Kategori 2 (2RHZES/1RHZE/5H3R3E3) Kategori 3 ( 2RHZE/4RH atau 6 RHE) Kategori 4 ( RHZES/ sesuai hasil uji resistensi + Obat lini 2 ( pengobatan minimal 18 bl) • Sisipan (RHZE) .

Hasil Pengobatan Tindak Lanjut • • • • • • Sembuh Pengobatan lengkap Meninggal Pindah DO Gagal .