Griffith RS, Norins AL, Kagan C. - Dermatologica. 1978;156(5):257-67.312-1200mg (single or multiple doses) beneficial effect in accelerating recovery
Lysine prophylaxis in recurrent herpes simplex labialis: a double-blind, controlledcrossover study
.Milman N, Scheibel J, Jessen O. - Acta Derm Venereol. 1980;60(1):85-71000mg longer recurrence-free rate
Subjective response to lysine in the therapy of herpes simplex
David E. Walsh*, Richard S. Griffith† and Ali Behforooz
- Oxford Journals Medicine Journalof Antimicrobial Chemotherapy Volume 12, Issue 5, p. 489-496 (1983)936mg 88% considered supplemental lysine effective
Failure of lysine in frequency in frequently recurrent HS infection. Treatment andprophylaxis
Arch Dermatol. 1984 Jan;120(1):48-51. - DiGiovanna JJ, Blank H.400mg tds = total 1200mg = fail(note the low dose separated throughout the day)
Treatment of recurrent herpes simplex infections with L-lysine monohydrochloride
.McCune MA, Perry HO, Muller SA, O'Fallon WM. - Cutis. 1984 Oct;34(4):366-731248mg effective at decreasing recurrence rate,624mg not effective
Lysine as a prophylactic agent in the treatment of recurrent herpes simplex labialis.
Thein DJ, Hurt WC. - Oral Surg Oral Med Oral Pathol. 1984 Dec;58(6):659-66.1000mg useful in reducing recurrence rate
Success of L-lysine therapy in frequently recurrent herpes simplex infection.Treatment and prophylaxis.
Griffith RS, Walsh DE, Myrmel KH, Thompson RW, Behforooz A. - Dermatologica.1987;175(4):183-90.1000mg tds = total 3000mg = success in all areas: lower recurrence, significantly reducedsymptoms and healing time
Clinical effectiveness of lysine in treating recurrent aphthous ulcers and herpeslabialis.
Wright EF. - Gen Dent. 1994 Jan-Feb;42(1):40-2; quiz 51-2.Helps reduce recurrence rate
Lysine for management of herpes labialis.
Tomblin FA Jr, Lucas KH - Am J Health Syst Pharm. 2001;58(4):298-300, 304.Tomblin and Lucas report in detail on the results of half a dozen studies of varying size,design and duration. According to Tomblin and Lucas, the studies showed lysine tended tobemore effective as a preventative for HSV than as a treatment for an outbreak, and thatresults were
.They noted that most of the more rigorous studies --- double-blind, placebo controlled and providing statistical analysis --- were small, and suggestedlarger, well-designed studies could provide a more definitive answer.
Will taking the amino acid supplement lysine prevent or treat the herpes simplex