CLINICAL ELECTROPHYSIOLOGIC TESTING
DEFINITION AND PURPOSE
Definition
:
Clinical electrophysiologic testing or electroneuromyography (ENMG)consist of the observation, analysis, and interpretation of the bioelectrical activity of muscle and nerve in response to volitional activation or electrical stimulation.The results of ENMG tests are integrated with clinical measurements, laboratoryfindings, and symptomatology inorder to assist in the establishment of a diagnosis andsubsequent plans of care. The ENMG results viewed in isolation are neither characteristicnor indicative of specific diseases or disorders. That is the ENMG findings alone will notestablish the diagnosis of the underlying pathology but rather supplement the findingsfrom numerous other clinical and laboratory tests used in differential diagnosis.
Purpose:
The main purpose of ENMG is to determine the integrity of specificcomponents of the neuromuscular system (α motoneurons and their axons, theneuromuscular junction, skeletal muscle, peripheral sensory nerve fibres, selectedreflexes, and certain central nervous system pathways). Electroneuromyographicexamination of these structures will assist the practioner in the determination of thelocation, magnitude, and chronicity of neuromuscular impairment.
EXTRACELLULAR AND INTRACELLULAR RECORDING TECHNIQUES
The bioelectrical responses of excitable tissue to volitional or electrically elicitedactivation are nerve and muscle action potentials occurring across the membrane of allsufficiently depolarized fibers. When muscle or nerve fibres are depolarized to threshold,
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