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• Fast before the endoscopy. You will need to stop drinking and eating four to eight hours
before your endoscopy to ensure your stomach is empty for the procedure.
• Stop taking certain medications. You will need to stop taking certain blood-thinning
medications in the days before your endoscopy. Blood thinners may increase your risk of
bleeding if certain procedures are performed during the endoscopy. If you have chronic
conditions, such as diabetes, heart disease or high blood pressure, your doctor will give
you specific instructions regarding your medications.
• Remove dentures and partial plates to facilitate passing the scope and preventing
injury
CONT’’’
• A randomized controlled trial of gastric lavage prior to endoscopy for
acute upper gastrointestinal bleeding: hypothesis that large volume
gastric lavage prior to endoscopy for acute upper gastrointestinal
bleeding would improve the quality of endoscopic examination
• Anesthetist visit: Anesthesia is one of the important components of
gastrointestinal endoscopic (GIE) procedures. The aim of anesthesia for
these procedures is to improve patient’s comfort and endoscopic
practice as well as patient and endoscopist satisfaction. The
requirement for anesthesia is dependent on the type and duration of
endoscopy, experience of endoscopist, and patient’s physical status.
• Intravenous fluids are routinely given empirically to the patients
undergoing colonoscopy or upper endoscopy: This common
practice will depend on patient’s physical status.
DURING AN UPPER GI ENDOSCOPY:
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Functions of Lower GIT
• Small Intestine. The two primary functions of the small
intestine are digestion and absorption (uptake of nutrients
from the gut lumen to the bloodstream).
• It extends from the pylorus to the ileocecal valve.
• The small intestine is composed of the duodenum, jejunum,
and ileum.
• The ileocecal valve prevents reflux of large intestine contents
into the small intestine.
• Absorption is the transfer of the end products of digestion
across the intestinal wall to the circulation. Most absorption
occurs in the small intestine.
• Monosaccharides (from carbohydrates),fatty acids (from fats),
amino acids (from proteins), water, electrolytes, vitamins, and
minerals are absorbed from small intestines.
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• The four parts of the large intestine are transverse
colon, ascending colon, descending colon, sigmoid
colon.
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Basic info about Colonoscopy
• Day of colonoscopy:
• Do not eat any solid food until after your colonoscopy.
• Take the second part of bowel preparation as instructed, starting 6 hours before
and finishing at least 4 hours before your colonoscopy appointment.
• After you complete the preparation do not eat or drink any other liquid or food.
• Arrive 1 hour before the scheduled time with an adult who will be available to
accompany you home.
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• A large number of bowel preparations are currently available
• The timing of administration is very important in determining the quality of bowel
preparation for colonoscopy.
• One report found that consumption of the purgative/laxative solution shortly before
undergoing colonoscopy had superior results than when larger intervals were used.
• Studies suggest that preparation must begin with dietary changes, and these
regimens generally incorporate clear liquids and low-residue foods for a period of 1
or more days prior to the procedure.
• These bowel preparations solutions work by drawing water into the intestine, which
in turn causes bowel distention and stimulates evacuation.
• The routine use of these agents has also fallen out of favor because of the risk of
explosion during electrosurgical procedures.
• Hydrogen gas is produced by bacterial fermentation of the nonabsorbed
carbohydrates in the colon, which in turn causes the risk of explosion.
• Stimulant laxatives, such as castor oil and senna, were once widely used in bowel
preparation but were not very effective and considered to be harsh.
• Their mechanism of action is to increase peristalsis, which then leads to the
secretion of fluid into the intestinal lumen. These products have by and large been
abandoned by most endoscopists.
• Hyperosmotic laxatives prepared with non-absorbable carbohydrates (mannitol,
sorbitol, lactulose), were also in use.
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• Oral gastrointestinal lavage preparations that use balanced
electrolyte solutions with polyethylene glycol (example of PEKOL in
our setting) have become one of the preferred methods of bowel
cleansing.
• Pekol is a nonabsorbable solution that will normally pass through the
intestines without net absorption or secretion.
• There are no or minimal fluids shifts although large volumes of Pekol
solutions must be consumed to have an effect, which can create
hemodynamic instability in susceptible patients.
• A number of studies have shown that Pekol solutions are effective and
reasonably tolerated by patients, and several commercial preparations
are available.
• Pekol has certain advantages compared with some older methods of
bowel preparation like not cause damage to the colonic mucosa.
• Major disadvantages of Pekol is patient tolerance, as large volumes
must be ingested to have an effect.
• Many individuals also find the taste to be rather unpleasant, even with
flavoring added.
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Assessing the quality of a bowel preparation
The stool coming out should look like the stuff you are eating and drinking -
clear, without many particles. You know you’re done when the stool coming
out is yellow, light, liquid and clear - like urine.
Yellow and
Light orange
clear, like
and mostly
urine
clear
11/10/2023 You’re Ready
Almost There
Practices at CHUB,
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Consequences of poor colonoscopy preparation