Volume 2 Issue: 4 (Apr 2013) | Page: 24 - 35

ISSN 2278 4500

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Dr. Jos Eizayaga (Argentina)

Dr. Silvia Waisse (Brazil) Dr. Leoni Bonamin (Brazil) Dr. Shivang Swaminarayan (India)

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Table of Contents
Studies you may like to read ............................................................................................................................ 26 Fundamental Research........................................................................................................................................ 26
1. Evaluation of the cytotoxicity and genotoxicity of aristolochic acid I - A component of

Aristolochiaceae plant extracts used in homeopathy .................................................................... 26

2. Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model

............................................................................................................................................................................. 26
3. Differences in Median Ultraviolet Light Transmissions of Serial Homeopathic Dilutions of

Copper Sulfate, Hypericum perforatum, and Sulfur ....................................................................... 26

4. Adaptive network nanomedicine: an integrated model for homeopathic medicine ......... 27

Clinical Research .................................................................................................................................................... 27

1. Acute electroencephalographic effects from repeated olfactory administration of

homeopathic remedies in individuals with self-reported chemical sensitivity ................... 27

2. Effectiveness and safety of a homeopathic drug combination in the treatment of chronic

low back pain. A double-blind, randomized, placebo-controlled clinical trial ..................... 28

3. Comparative Effectiveness of Homoeopathic vs. Conventional Therapy in Usual Care of

Atopic Eczema in Children: Long-Term Medical and Economic Outcomes ........................... 29 Drug Standardization ........................................................................................................................................... 29
1. Feasibility study of nonclinical safety assessments on homeopathic preparations using

the example of protoanemonin in Pulsatilla pratensis L. ............................................................. 29

2. Lectin activity of homeopathy drugs .................................................................................................... 30

Veterinary Research ............................................................................................................................................. 30

1. Successful management of refractory cases of canine demodicosis with homeopathy

medicine Graphitis ....................................................................................................................................... 30 Primary Health Care ............................................................................................................................................. 30

1. Knowledge of the municipal health managers about the National Policy on Integrative and

Complementary Practices and its influence on the provision of homeopathy in the Local Unified Health System .................................................................................................................................. 30 Review .......................................................................................................................................................................... 31
1. Economic evaluations of homeopathy: a review ............................................................................... 31 2. Homoeopathic Research-Understanding the Challenges ............................................................... 31 3. Homeopathic Treatments for Depression ............................................................................................ 32

Journal Updates ....................................................................................................................................................... 32 24

International Journal of High Dilution Research...................................................................................... 32 1. Transition time..................................................................................................................................... 32 2. A Qualitative Systematic Review of the Homeopathic Outcome Studies in Patients with HIV/AIDS .................................................................................................................................................. 32 3. Homeopathy in Brazil: inquiry into its academic production ............................................ 32 4. Prestimulation of wheat seedlings with gibberellic acid followed by application of an agitated high dilution of the same hormone ......................................................................................... 32 News .............................................................................................................................................................................. 32 Events ........................................................................................................................................................................... 33

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Studies you may like to read Fundamental Research

Evaluation of the cytotoxicity and genotoxicity of aristolochic acid I - A component of Aristolochiaceae plant extracts used in homeopathy Nitzsche D, Melzig MF, Arlt VM. Environ Toxicol Pharmacol. 2013 18;35(2):325334. Abstract The medicinal plants Aristolochia clematitis L. as well as Asarum europaeum L., representatives of the plant family Aristolochiaceae and mentioned in the German Homeopathic Pharmacopeia, contain aristolochic acid. We found that the mother tinctures of A. clematitis and A. europaeum inhibited DNA synthesis in human hepatoma HepG2 cells in a dose-dependent manner. One of the components of the plant extract, aristolochic acid I (AAI), is linked to the development of nephropathy and urothelial cancer in humans. Therefore, we also evaluated the cytotoxicity and genotoxicity of AAI in HepG2 cells. Cell proliferation was inhibited concentration-dependently by AAI using BrdUELISA and colony forming assay. AAI formed DNA adducts (measured by (32)P-postlabeling), induced chromosomal aberrations (micronuclei) and DNA strand breaks. DNA damage induced by AAI led to an arrest of cells in the S-phase which was associated with the increased expression of p53 and p21 proteins. The results are discussed under consideration of former studies. Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model Bonamin LV, Sato C, Zalla Neto R, Morante G, Cardoso TN, de Santana FR, Coelho Cde P, Osugui L, Popi AF, Hurtado EC, Mariano M.

Evid Based 2013;686018

Complement

Alternat

Med.

Abstract The present study analyzed the immune modulation mechanisms of thymulin 5CH in a granuloma experimental model. Male adult Balb/c mice were inoculated with BCG into the footpad to induce granuloma, which was quantitatively evaluated. The phenotypic characterization of phagocyte, T- and Blymphocyte populations in the peritoneum, and local lymph node was done by flow cytometry. During all experimental periods, thymulin 5CH and vehicle (control) were given ad libitum to mice, diluted into the drinking water (1.6 10(17)M). After 7 days from inoculation, thymulintreated mice presented reduction in the number of epithelioid cytokeratine-positive cells (P = 0.0001) in the lesion, in relation to young phagocytes. After 21 days, the differentiation of B1 peritoneal stem cells into phagocytes reached the peak, being higher in thymulin-treated mice (P = 0.0001). Simultaneously, the score of infected phagocytes in the lesion decreased (P = 0.001), and the number of B1-derived phagocytes, CD4+ and CD8+ T lymphocytes in the local lymph node increased in relation to control (P = 0.0001). No difference was seen on the CD25+ Treg cells. The results show that thymulin 5CH treatment is able to improve the granuloma inflammatory process and the infection remission, by modulating local and systemic phagocyte differentiation. Differences in Median Ultraviolet Light Transmissions of Serial Homeopathic Dilutions of Copper Sulfate, Hypericum perforatum, and Sulfur Klein SD, Sandig A, Baumgartner S, Wolf U. Evid Based Complement Alternat 2013;2013:370609

Med.

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Abstract Homeopathic remedies are produced by potentising, that is, the serial logarithmic dilution and succussion of a mother tincture. Techniques like ultraviolet spectroscopy, nuclear magnetic resonance, calorimetry, or thermoluminescence have been used to investigate their physical properties. In this study, homeopathic centesimal (c) potencies (6c to 30c) of copper sulfate, Hypericum perforatum, and sulfur as well as succussed water controls were prepared. Samples of these preparations were exposed to external physical factors like heat, pressure, ultraviolet radiation, or electromagnetic fields to mimic possible everyday storage conditions. The median transmissions from 190nm to 340nm and 220nm to 340nm were determined by ultraviolet light spectroscopy on five measurement days distributed over several months. Transmissions of controls and potencies of sulfur differed significantly on two of five measurement days and after exposure to physical factors. Transmissions of potencies exposed to ultraviolet light and unexposed potencies of copper sulfate and Hypericum perforatum differed significantly. Potency levels 6c to 30c were also compared, and wavelike patterns of higher and lower transmissions were found. The Kruskal-Wallis test yielded significant differences for the potency levels of all three substances. Aiming at understanding the physical properties of homeopathic preparations, this study confirmed and expanded the findings of previous studies. Adaptive network nanomedicine: an integrated model for homeopathic medicine Bell IR, Schwartz GE. Front Biosci (Schol Ed). 2013 Jan 1;5:685-708. Abstract This paper presents an evidence-based model for the nature and mode of action of homeopathic remedies. Recent studies reveal that homeopathic

remedies contain nanoparticles (NPs) of source materials formed by "top-down" mechanical grinding in lactose and/or succussion (forceful agitation) in ethanolic solutions. Silica nanostructures formed during succussions in glass and/or biosynthesized by specific plant extract tinctures also may acquire and convey epitaxial information from remedy source materials into higher potencies. NPs have enhanced bioavailability, adsorptive capabilities, adjuvant reactivity, electromagnetic and quantum properties compared with their bulk forms. NPs induce adaptive changes in the organism at nontoxic doses (hormesis), serving as salient, low level danger signals to the biological stress response network. Activation of stress response effectors, including heat shock proteins, inflammation, cytokines and neuroendocrine pathways, initiate beneficial compensatory reactions across the interconnected networks of the organism as a complex adaptive system. Homeopathic remedies act by stimulating hormetic adaptive rather than conventional pharmacological effects. Updating terminology from "homeopathy" to "adaptive network nanomedicine" reflects the integration of this historical but controversial medical system with modern scientific findings.

Clinical Research
Acute electroencephalographic effects from repeated olfactory administration of homeopathic remedies in individuals with self-reported chemical sensitivity Bell IR, Brooks AJ, Howerter A, Jackson N, Schwartz GE. Altern Ther Health Med. 2013 Jan-Feb;19(1):4657. Abstract Background: Homeopaths report that individuals with heightened self-reported

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environmental chemical intolerance (CI) exhibit increased reactivity to homeopathic remedies. Persons high in CI sensitize their electroencephalographic (EEG) alpha responses to repeated intermittent chemical exposures. Primary study objective: The present feasibility study explored interactions between CI and one of two specific homeopathic remedies over time (Sulphur or Pulsatilla nigricans [Pulsatilla]). Design: This study used a two-arm, double-blind, placebo-controlled repeated measures design. Intervention Participants underwent a series of three once-weekly sessions during which they repeatedly sniffed one remedy (6c, 12c, 30c; one potency per week) matched to their Homeopathic Constitutional Type Questionnaire (CTQ) type and two solvent controls (distilled water and a waterethanol [95%] solution). Within sessions, remedies and control solvents were administered via 2-second sniffs (eight sniffs of each of four different succussion levels per potency, in randomized order). Participants: Participants were college student volunteers (N = 96, ages 18-30, both sexes), screened for good health and relatively elevated Sulphur or Pulsatilla symptom pattern scores on the Homeopathic Constitutional Type Questionnaire (CTQ). Participants also completed a validated trait CI scale. Primary outcome measures: Average 19-lead relative EEG alpha power (alpha 1 8-10 Hz; alpha 2 10-12 Hz). Results: Trait CI interacted significantly with time factors for each remedy (both over visit weeks and over sniff cycles during sessions). The patterns were nonlinear and differed between the two remedies. Individuals high in CI showed greater variability over time in remedy EEG alpha effects than did those low in CI. Conclusion: The data suggest that CI, with an underlying susceptibility to time-dependent sensitization and oscillatory responses, could contribute to nonlinear dose-response patterns

and inconsistent reproducibility of homeopathic clinical care and research. Effectiveness and safety of a homeopathic drug combination in the treatment of chronic low back pain. A double-blind, randomized, placebo-controlled clinical trial Beer AM, Fey S, Zimmer M, Teske W, Schremmer D, Wiebelitz KR. MMW Fortschr Med. 2012 Jun 28;154 Suppl 2:4857. [Article in German] Abstract Background: The homeopathic drug combination Lymphdiaral Basistropfen is established in the treatment of edema and swellings. This is the first time the effectiveness and safety was investigated in the treatment of chronic low back pain. Methods: The study is a randomized, doubleblind, placebo-controlled trial. From December 2003 to May 2007 248 patients aged 18 to 75 years were screened, 228 were randomized, 221 started therapy, in 192 the progress was measured (103 verum vs. 89 placebo), 137 completed the study (72 verum vs. 65 placebo). They received 10 drops of verum or placebo solution three times daily for 105 days additionally to an inpatient complex naturopathic treatment. Results: The hannover functional ability questionnaire score (primary outcome measure) tends to increase in the intention-to-treatanalysis (verum: 6.6 vs. placebo: 3.4; p = 0.11) and increases significantly in the per-protocolanalysis (verum: 9.4 vs. placebo: 4.1; p = 0.029). The treatment was well tolerated (92.9% vs. 95.4%). The incidence of adverse reactions and serious adverse reactions was similar in both treatment groups. Conclusions: This first randomized, doubleblind, placebo-controlled trial shows, that the

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homeopathic drug combination can improve the treatment of chronic low back pain. Comparative Effectiveness of Homoeopathic vs. Conventional Therapy in Usual Care of Atopic Eczema in Children: Long-Term Medical and Economic Outcomes Roll S, Reinhold T, Pach D, Brinkhaus B, Icke K, Staab D, Jckel T, Wegscheider K, Willich SN, Witt CM. PLoS One. 2013;8(1):e54973. Abstract Background: One in five children visiting a homeopathic physician suffers from atopic eczema. Objectives: We aimed to examine the long-term effectiveness, safety and costs of homoeopathic vs. conventional treatment in usual medical care of children with atopic eczema. Methods: In this prospective multi-centre comparative observational non-randomized rater-blinded study, 135 children (48 homoeopathy, 87 conventional) with mild to moderate atopic eczema were included by their respective physicians. Depending on the specialisation of the physician, the primary treatment was either standard conventional treatment or individualized homeopathy as delivered in routine medical care. The main outcome was the SCORAD (SCORing Atopic Dermatitis) at 36 months by a blinded rater. Further outcomes included quality of life, conventional medicine consumption, safety and disease related costs at six, 12 and 36 months after baseline. A multilevel ANCOVA was used, with physician as random effect and the following fixed effects: age, gender, baseline value, severity score, social class and parents' expectation. Results: The adjusted mean SCORAD showed no significant differences between the groups at 36 months (13.7 95% CI [7.9-19.5] vs. 14.9 [10.419.4], p=0.741). The SCORAD response rates at

36 months were similar in both groups (33% response: homoeopathic 63.9% vs. conventional 64.5%, p=0.94; 50% response: 52.0% vs. 52.3%, p=0.974). Total costs were higher in the homoeopathic versus the conventional group (months 31-36 200.54 Euro [132.33-268.76] vs. 68.86 Euro [9.13-128.58], p=0.005). Conclusions: Taking patient preferences into account, while being unable to rule out residual confounding, in this long-term observational study, the effects of homoeopathic treatment were not superior to conventional treatment for children with mild to moderate atopic eczema, but involved higher costs.

Drug Standardization
Feasibility study of nonclinical safety assessments on homeopathic preparations using the example of protoanemonin in Pulsatilla pratensis L. D. Schrenk, K.-H. Merz, K. Jochims Regulatory Toxicology and Pharmacology, Available online 25 March 2013 Abstract Homeopathy is a world-wide available form of complementary therapy, which has a tradition of 200 years. Due to the long history of clinical use, i.e. reflected by the first edition of the Homeopathic Pharmacopoeia of the US of 1914, the conduct of toxicological studies is not required if the safety has been otherwise substantiated. The aim of this article is to establish a risk assessment procedure without full toxicological examination, using homeopathic preparations from Pulsatilla pratensis L. as an example. The literature review shows that protoanemonin is the most relevant constituent of these plants regarding potential toxicity. Based on structural alerts protoanemonin is classified as a Cramer class III compound with the

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threshold of toxicological concern (TTC) of 180 g/day in adults. Neither computer aided toxicology methods (Toxtree and Derek Nexus) nor a literature search revealed any evidence of genotoxic, carcinogenic or teratogenic potential of protoanemonin. The protoanemonin exposure from a maximum daily dose of a typical homeopathic preparation of P. pratensis L. does not exceed the TTC. The presented method is transparent, reproducible and applicable to other homeopathic substances as a use-case scenario for computational toxicology in order to evaluate an approach for safety assessment of homeopathic medicinal products. Keywords: Homeopathy; Pulsatilla; Protoanemonin; Nonclinical safety; TTC-concept; Structureactivity relationship Lectin activity of homeopathy drugs Jaiswal A.G. International Multidisciplinary Research Journal 2012, 2(12):19-20 Abstract Lectins are useful for protective effect of plants which are similar to antibodies. They are also helping in the selective binding of Rhizobia during the initiation of root nodules of legume plants. Homeopathic mother tinctures are used to find out their lectin activities, they are- Arnica montana, Cassia sophara, Caulophullum, Ficus indica, Ficus religiosa, Nux vomica, Solanum xantocarpum, Blata oientalis, Spongia tosta and Urtica urens. Nobody tried for mother tinctures for the purpose of lectin activity, this is a first ever attempt to study the lectin activity to show co-relation with remedial effect. Keywords: Lectin, Homeopathic, mother tinctures, phytohemagglutains

Veterinary Research
Successful management of refractory cases of canine demodicosis with homeopathy medicine Graphitis Rakesh Ranjan, Kirti Dua, Sujata Turkar, Harkirat Singh, L. D. Singla Journal of Parasitic Diseases, March 2013 Abstract Canine demodicosis is a refractory skin disease caused by excessive proliferation of mite Demodex canis. Despite availability of several treatment options, the disease poses a great challenge to clinicians for its long term management as some drugs may be ineffective or toxic. Present report describes successful treatment of two refractory cases of canine demodicosis using homeopathy medicine. After oral administration of Graphitis 200 C two drops once daily for 2 months, complete cure from the disease was observed. No adverse health effects of the medication were recorded during the treatment. Thus, it may be concluded that homeopathy medicine may be used safely for long-term management of canine demodicosis.

Primary Health Care

Knowledge of the municipal health managers about the National Policy on Integrative and Complementary Practices and its influence on the provision of homeopathy in the Local Unified Health System Galhardi WM, Barros NF, Leite-Mor AC. Cien Saude Colet. 2013 Jan;18(1):213-20. [Article in Portuguese] Abstract The social determinants of the health-disease process and the challenge of comprehensive care have led the World Health Organization to

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propose Complementary and Alternative Medicines to be included in health policies. In Brazil in 2006 the National Policy on Integrative and Complementary Practices (PNPIC) was published. It is a tool for the institutionalization of homeopathy in the Unified Health System (SUS). This paper analyzes the knowledge of health managers of municipalities of So Paulo on PNPIC, and its influence on homeopathic care. In 2008, the municipalities that performed homeopathic consultations from 2000 to 2007 were identified in DATASUS, managers were interviewed and the results were analyzed quantitatively and qualitatively: of the 645 municipalities, 47 had offered homeopathy and 42 of them were interviewed. Of these, 26% knew about PNPIC, 31% knew little, 41% were unaware of it. It should be stressed that those aware of it stated that they use PNPIC to: instruct the local government about homeopathy; the construction of specific legislation and the increase in homeopathic services. The conclusion is that PNPIC is unknown by health managers and those that know it use it to make known the homeopathic medical rationale and justify its application in the SUS.

Review
Economic evaluations of homeopathy: a review Viksveen P, Dymitr Z, Simoens S. Eur J Health Econ. 2013 Feb 10. [Epub ahead of print] Abstract Context: Economic evaluations of commonly used complementary and alternative medicine (CAM) therapies such as homeopathy are needed to contribute to the evidence base on which policy makers, clinicians, health-care payers, as

well as patients base their health-care decisions in an era of constrained resources. Objectives: To review and assess existing economic evaluations of homeopathy. Methods: Literature search was made to retrieve relevant publications using AMED, the Cochrane Library, CRD (DARE, NHS EED, HTA), EMBASE, MEDLINE, and the journal Homeopathy (former British Homoeopathic Journal). A hand search of relevant publications was carried out. Homeopathy researchers were contacted. Identified publications were independently assessed by two authors. Results: Fifteen relevant articles reported on 14 economic evaluations of homeopathy. Thirteen studies reported numbers of patients: a total of 3,500 patients received homeopathic treatment (median 97, interquartile range 48-268), and 10 studies reported on control group participants (median 57, IQR 40-362). Eight out of 14 studies found improvements in patients' health together with cost savings. Four studies found that improvements in homeopathy patients were at least as good as in control group patients, at comparable costs. Two studies found improvements similar to conventional treatment, but at higher costs. Studies were highly heterogeneous and had several methodological weaknesses. Conclusions: Although the identified evidence of the costs and potential benefits of homeopathy seemed promising, studies were highly heterogeneous and had several methodological weaknesses. It is therefore not possible to draw firm conclusions based on existing economic evaluations of homeopathy. Recommendations for future research are presented. Homoeopathic Research-Understanding the Challenges Kaur H (2013) J Homeop Ayurv Med 2:118.

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J Homeop Ayurv Med 2:117 Abstract Over the last decade, documented research has gained importance in every system, more so in medicine. Homeopathy is no exception, as evident from a sharp increase in the number of researches being published in various homeopathic journals. The question why to research has well been overcome by the community taking keen interest in not only carrying out researches, but also sharing those through publications and presentations. However, another question what to research is getting more and more relevant for various reasons. One, because even though the numerous researches conducted in homeopathy have taken homeopathy to a higher level, much remains desirable to take it to the level of international acceptance. This calls for a serious analysis of what exactly should be the elements on which the research needs to be focused upon, in order to gain maximum acceptance. Two, there are many areas that have been exhaustively researched and researching those further might not be as productive as investing the same amount of time, energy and resources on some other more relevant and vital research area. This is largely true for the clinical researches on various oft-repeated conditions. The paper aims at appraising the homeopaths interested in research about the various challenges lying ahead for homeopathy, the research in which could prove to be more apt and worthwhile for both the researcher and the profession. Homeopathic Treatments for Depression Elena Gromova Abstract The paper presents the main facts from history of homeopathic medicinal approach, its fundamental assumptions and limitations and considers homeopathic substances with the potential to alleviate symptoms of major depression and anxiety comorbidities. Clinical aspects of homeopathic substances, such as their safety and efficacy, will be addressed using the available empirical data, and regulatory standards applicable to marketing and sale of these substances will be briefly addressed as well. The paper will also supply arguments in favor of and against the use of homeopathic substances to treat depression.

Journal Updates
International Journal of High Dilution Research
1. Transition time 2. A Qualitative Systematic Review of the
Homeopathic Outcome Studies in Patients with HIV/AIDS academic production

3. Homeopathy in Brazil: inquiry into its 4. Prestimulation of wheat seedlings with

gibberellic acid followed by application of an agitated high dilution of the same hormone

News
1. Jeremy Hunt, new health secretary, called for the NHS to be dismantled and supports homeopathy

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2. Comprehensive review of RCTs in homeopathy forms the basis for extensive programme of research 3. MP triggers homeopathy dispute at science committee 4. Civil servants suppress evidence on homeopathy on NHS website after lobbying from princes charity 5. Doctors want homeopathy on the NHS to end 6. Professor Edzard Ernst Removed from Homeopathy Editorial Board 7. Debate about Homeopathy: Mere Placebo or Great Medicine? 8. How Can Homeopathy Be Placebo When It Cures Farm Animals? 9. Homeopathy Artifacts Photographs

Events
Wed Apr 3, 2013 The Polaris Institute Objective Observer Practitioner Training Program-03 Year Clinical Based Programme The Polaris Institute for Homeopathys Objective Observer Practitioner Training Program April 10, 2013 to March 19, 2014 The Foundation Year of Our Three Year Clinical-Based Course The Objective Observer Course is a complete and comprehensive practitioner training program, which prepares its students to be successful and proficient professional homeopaths. Instructor: Douglas Falkner, MD, MHom Email: drfalknermd@gmail.com Phone: 541-552-1400 Visit: www.polarisinstitute.com Mon Apr 8, 2013 AMCH MODERN PRACTICE 5:00 - 7:00 pm pacific time Karen Allen, Iris Bell, Miranda Castro, Jerry Kantor, Amy Lansky, Todd Rowe and Gabrielle Traub Contact: Leslie at 714-577-8853 or email whncourses@whnow.com Tue Apr 16, 2013 Repertorization & Case Analysis using Opus Homeopathic Software With Kim Elia Contact: schools@whnow.com, (415) 585-8075 (Pacific time) Register online: http://www.wholehealthnow.com/event/toronto Wed Apr 17 Sun Apr 21, 2013 Cases with the diagnosis of Autism ~ The Use of Some Oil and Carbon Remedies and Others Massimo Mangialavori, N. Andover, MA Sponsored by New England Homeopathic Academy (NEHA) Contact: Betty Wood 978-635-0605

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mailto:neha.homeopathy@gmail.com Fri Apr 19, 2013 The 8th Annual Joint American Homeopathic Conference, Reston, VA Contact: National Center for Homeopathy email: office@nationalcenterforhomeopathy.org Website: www.nationalcenterforhomeopathy.org Phone: (703) 548-7790 Mon Apr 22, 2013 Repertorization and Case Analysis using Opus Homeopathic Software / Live Training A live training with Kim Elia 10 am - 4 pm in Reston, VA following the JAHC $25 and include a delicious, vegetarian lunch Contact: Mary Johnston, 415-585-8075 (Pacific time) Email: schools@whnow.com http://www.wholehealthnow.com/event/reston.html Fri Apr 26 Sun Apr 28, 2013 10 WEEKEND CERTIFICATE COURSE 2013-2014: New England School of Homeopathy Course designed for both the beginner and more experienced homeopaths for understanding classical homeopathy called Cycles and Segments. Instructors: Drs. Paul Herscu ND and Amy Rothenberg ND Mail to: nesh@nesh.com 413-256-5949, fax 860-253-5041 #1 April 26-28, 2013 #2 June 7-9, 2013 #3 August 2-4, 2013 #4 October 4-6, 2013 #5 December 6-8, 2013 #6 February 2014, exact dates TBA #7 April 2014, exact dates TBA #8 June 2014, exact dates TBA #9 August 2014, exact dates TBA #10 October 2014, exact dates TBA Sat Apr 27, 2013 Success in Homeopathy: Four Homeopaths, Four Cured Cases Bastyr University, Kenmore, WA Instructors: Doug Brown, CCH RSHom(NA) FNP Richard Mann, ND DHANP

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Nancy Mercer, ND, DHANP Lucy Vaughters, PA-C MA-T For further details and registration please visit the below website. Website: http://www.bastyr.edu/civicrm/event/info?reset=1&id=593

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