BME 2200 - Homework #0 Due: Wednesday, January 19, beginning of class

This assignment is a pre-test to evaluate your knowledge of the Conservation Laws. The purpose of this pre-test is to assess how the course helps to contribute to your understanding and application of the Conservation Laws. This work is sponsored by a NSF Division of Undergraduate Education grant. Do NOT look at or use the Rice University course notes or the book by Himmelblau to complete this assignment. Do NOT talk with your classmates or other students. Do NOT work more than 2 hrs on this homework. If you do not know how to do the problem, sketch a diagram and describe how you might solve the problem. A score of 100 will be assigned if a good-faith effort is made.

1. Venturi meters are used to measure flow rates of turbulent fluids in small pipes. The design of a venturi meter is based on the fact that when a pipe is constricted, the fluid velocity increases and the pressure decreases across the constriction. By measuring the height difference, h, of the manometer fluid between positions 1 and 2, the velocity of the fluid before the constriction can be determined. The sections of pipe before and after the constriction are connected with a U-tube manometer filled with liquid of density, M. The fluid flowing through the pipe has density, F. Before the constriction, the cross-sectional area of the pipe is A1 and the velocity of the fluid is v1. After the constriction, the cross-sectional area of the pipe is A2 and the velocity of the fluid is v2. Write an equation for the velocity, v1, as a function of M, F, h, g (gravitational constant), A1 and A2. Assume that the pressure along position 1 is P1 and that the pressure along position 2 is P2. Assume no other forces act on the system. The manometer fluid is static.

2. Cell biomass, represented as CHNO, is grown in a bioreactor (Doran). , , , and are the numbers specifying the molecular formula. The molecular weight of CHNO is 91.34 g/mol. There are two inlet streams to the bioreactor. The first inlet stream contains glucose and ammonia; the second inlet stream contains air. Glucose, C6H12O6, is added to the reactor at a mass flow rate of 144 g/min. Ammonia, NH3, is added to the reactor at a mass flow rate of 5.10 g/min. Air is added at a volumetric flow rate of 1.00 x 105 cm3/min. The composition of the air is 21 vol% O2 and 79 vol% N2. There are two outlet streams from the bioreactor. One outlet stream contains CHNO, excess C6H12O6, and H2O; the other is a gas stream and contains O2, N2, and CO2. The outlet mass flow rate of glucose, C6H12O6, is 74.9 g/min. The outlet mass flow rate of water, H2O, is 26.6 g/min. The volumetric flow rate of the outlet gas stream is 1.131 x 105 cm3/min. The composition of the gas is 5.2 vol% O2 and 69.9 vol% N2. The following biochemical reaction takes place in the bioreactor: C6H12O6 + O2 + NH3 CHNO + H2O + CO2 Ammonia is the limiting reactant and is completely consumed in the reaction. The bioreactor is in steady-state operation. Assume that the density of air and of the other gaseous components is 0.0012 g/cm3. air = N2 = O2 = CO2 = 0.0012 g/cm3. a. Solve for the inlet molar flow rates. b. Solve for the outlet molar flow rates. c. Solve for the stoichiometric coefficients that correctly balance the biochemical reaction. d. Solve for the values of , , , and .