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  • Inflammation: Acute & Chronic

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    This document discusses acute and chronic inflammation. It covers the general features of inflammation including its goals of eliminating injurious agents and restoring function. It also discusses the historical highlights of inflammation from ancient Greek and Roman physicians to Rudolph Virchow's cellular theory of inflammation. The document outlines the components and process of acute inflammation including stimuli, vascular changes, cell events like leukocyte extravasation and phagocytosis. It notes how defects in leukocyte function can lead to medical issues and discusses how acute inflammation ends through short-lived mediators, endogenous anti-inflammatory substances, and genetic control. Finally, it states that inflammation has significant medical implications.

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    Inflammation i

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    This document discusses acute and chronic inflammation. It covers the general features of inflammation including its goals of eliminating injurious agents and restoring function. It also discusses the historical highlights of inflammation from ancient Greek and Roman physicians to Rudolph Virchow's cellular theory of inflammation. The document outlines the components and process of acute inflammation including stimuli, vascular changes, cell events like leukocyte extravasation and phagocytosis. It notes how defects in leukocyte function can lead to medical issues and discusses how acute inflammation ends through short-lived mediators, endogenous anti-inflammatory substances, and genetic control. Finally, it states that inflammation has significant medical implications.

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    Attribution Non-Commercial (BY-NC)
    Download as PPT, PDF, TXT or read online from Scribd
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    250 views65 pages

    Inflammation: Acute & Chronic

    Uploaded by

    uagmed2012
    This document discusses acute and chronic inflammation. It covers the general features of inflammation including its goals of eliminating injurious agents and restoring function. It also discusses the historical highlights of inflammation from ancient Greek and Roman physicians to Rudolph Virchow's cellular theory of inflammation. The document outlines the components and process of acute inflammation including stimuli, vascular changes, cell events like leukocyte extravasation and phagocytosis. It notes how defects in leukocyte function can lead to medical issues and discusses how acute inflammation ends through short-lived mediators, endogenous anti-inflammatory substances, and genetic control. Finally, it states that inflammation has significant medical implications.

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    of 65

    INFLAMMATION:

    ACUTE & CHRONIC


    R. HUGO MARTÍNEZ LOZANO, M.D.

    August 30, 2006


    INFLAMMATION
    LEARNING OBJECTIVES:
    I) GENERAL FEATURES
    II) HISTORICAL HIGHLIGHTS
    III) ACUTE INFLAMMATION
    - Stimuli
    - Vascular changes
    - Cell events
    IV) END OF ACUTE INFLAMMATION
    V) ¡¡¡MEDICAL SIGNIFICANCE!!!
    - Ref: pp. 48-62 & Lecture’s information.
    INFLAMMATION
    I.- GENERAL FEATURES:
    - DEFINITION: Reaction vs injurious agents

    Vasc. & cell changes


    Systemic reactions
    - GOALS: - Elimination of the injurious agent
    - Restitution of the function
    - COMPONENTS – Vascular

    - Cellular
    - FORMS: A & C
    INFLAMMATION
    II) HISTORY
     Aulus Cornelius

    Celsus
    INFLAMMATION
    II) HISTORY:
    RUDOLPH VIRCHOW
    INFLAMMATION
    II) HISTORY
    Elie Metchnikoff
    INFLAMMATION
    II) HISTORY
    Paul Ehrlich
    INFLAMMATION
    III) ACUTE INFLAMMATION:
    COMPONENTS:
    - FLUIDS, PROTEINS

    - STIMULI

    - VASCULAR CHANGES

    - CELL EVENTS: - LEUC. EXTRAV.

    - PHAGOCYTOSIS
    - DEFECTS IN LEUCOCYTARY FUNCTION
    BRAIN
    EDEMA
    BONE
    MARROW
    DEFECTS OF LEUCOCYTE
    FUNCTIONS
    GENETIC:
    - CHRONIC GRANULOMATOUS DIS.

    - CHEDIAK-HIGASHI SYNDROME

    ACQUIRED:
    - MALNUTRITION

    - DIABETES

    - AIDS, MALIGNANCY, ETC.


    INFLAMMATION
    IV) THE END…
    - SHORT LIFE OF MEDIATORS
    - ENDOGENOUS ANTI-INFLAMMATORY S.
    - COLINERGIC STIMULI
    - GENETIC CONTROL
    INFLAMMATION
    V) MEDICAL SIGNIFICANCE…
    GLOTIS: EDEMA
    MULTIFOCAL
    PNEUMONIA
    (BRONCHO-
    PNEUMONIA)
    PULMONARY
    ABSCESS
    PURULENT
    PERICARDITIS
    PERICARDIAL
    ADHESIONS
    ULCERATIVE ESOPHAGITIS
    CROHN’S
    DISEASE
    QUESTIONS?

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