Naturally Occurring Tyzzer’s Disease in Cotton-top Tamarins(
Vol 57, No 1February 2007. transmural, necrotizing typhlocolitis accompanied bymyocarditis and hepatitis..
Animal Models for HIV AIDS: A Comparative Review.
Vol 57, No1 February 2007. Viruses discussed are grouped as causing (1)nonlentiviral immunodeficiency-inducing diseases, (2) naturallyoccurring pathogenic infections, (3) experimentally induced lentiviralinfections, and (4) nonpathogenic lentiviral infections.
Changes in the Titer of Anti–B Virus Antibody in CaptiveMacaques (Macaca fuscata, M. mulatta, M. fascicularis). Vol57, No 1 February 2007
. B virus (Cercopithecine herpesvirus 1; BV).
-herpesvirus subfamily and usually causes mild or asymptomaticinfection in its natural macaque host. However, BV infection in humansusually develops as a fatal centralnervous system infection and for this reason BV is classifiedas a biosafety level–4 pathogen.
Dermal Melanocytosis in Japanese Monkeys (
Vol 57, No 3 June 2007. the epidermis lacked melanocytes, but thedermis had numerous melanocytes with abundant melanin. Activatedmelanocytes with well-developed dendrites were distributedthroughout the upper part of the dermal layer. Melanocytes were notarranged in clusters, and elastic and collagen fibers in the dermisshowed no histological abnormalities.
Increased Production of 11
-hydroxysteroid DehydrogenaseType 2 in the Kidney Microsomes of Squirrel Monkeys (
Vol 58, No 2April 2008. In squirrel monkeys (Saimiri spp.), cortisol circulates atlevels much higher than those seen in man and other Old Worldprimates, but squirrel monkeys exhibit no physiologic signs of themineralocorticoid effects of cortisol. 11
-hydroxysteroiddehydrogenase type 2 (11
-HSD2), which converts cortisol to theinactive metabolite, cortisone. Pharmacologic inhibition of 11
-HSD2,inactivating mutations in 11
-HSD2, or saturation of the enzyme byhigh cortisol concentrationsresults in inappropriate activation of MR by cortisol and leads todevelopment of hypertension and electrolyte imbalance.
Pathology of Captive Moustached Tamarins (Saguinus mystax).Vol 58, No 2 April 2008
. Colitis cystica profunda (CCP), a diseasethat affects humans and is characterized by the presence of mucin-filled epithelial downgrowths and cysts in the colonic submucosa, was