Clinical practice recommendations forbipolar disorder
Malhi GS, Adams D, Lampe L, Paton M, O
Connor N, Newton LA,Walter G, Taylor A, Porter R, Mulder RT, Berk M. Clinical practicerecommendations for bipolar disorder.
To provide clinically relevant evidence-based recommen-dations for the management of bipolar disorder in adults that areinformative, easy to assimilate and facilitate clinical decision-making.
A comprehensive literature review of over 500 articles wasundertaken using electronic database search engines (e.g. MEDLINE,PsychINFO and Cochrane reviews). In addition articles, book chaptersand other literature known to the authors were reviewed. The ﬁndingswere then formulated into a set of recommendations that weredeveloped by a multidisciplinary team of clinicians who routinely dealwith mood disorders. These preliminary recommendations underwentextensive consultative review by a broader advisory panel that includedexperts in the ﬁeld, clinical staﬀ and patient representatives.
The clinical practice recommendations for bipolar disorder(bipolar CPR) summarise evidence-based treatments and provide asynopsis of recommendations relating to each phase of the illness.They are designed for clinical use and have therefore been presentedsuccinctly in an innovative and engaging manner that is clear andinformative.
These up-to-date recommendations provide an evidence-based framework that incorporates clinical wisdom and considerationof individual factors in the management of bipolar disorder. Further,the novel style and practical approach should promote their uptakeand implementation.
G. S. Malhi
, D. Adams
, M. Paton
, L. A. Newton
, A. Taylor
, R. Porter
,R. T. Mulder
, M. Berk
CADE Clinic, Department of Psychiatry, Royal NorthShore Hospital, St Leonards, NSW, Australia,
NorthernSydney Central Coast Mental Health Drug and Alcohol,Northern Sydney Cental Coast Area Health Service,Sydney, NSW, Australia,
Discipline of PsychologicalMedicine, University of Sydney, Sydney, NSW,Australia,
Sydney South West Area Health Service,Sydney, NSW, Australia,
Child and Adolescent MentalHealth Services, NSCCAHS, Sydney, NSW, Australia,
Department of Psychological Medicine, University ofOtago, Christchurch, New Zealand,
MelbourneUniversity, Barwon Health and the Geelong Clinic,Geelong, Victoria, Australia,
Orygen Research Centre,University of Melbourne, Melbourne, Victoria, Australiaand
Mental Health Research Institute, Melbourne,Victoria, AustraliaKey words: bipolar disorder; treatmentrecommendations; clinical practice guidelines;evidence-based reviewProfessor Gin S Malhi, CADE Clinic, Level 5, Building36, Royal North Shore Hospital, St Leonards, Sydney,NSW 2065, Australia.E-mail: email@example.com
The management of bipolar disorder should be based on an integration of evidence-based data andclinical experience.
Once a diagnosis of bipolar disorder is suspected it is important to
promptly. Action involvescareful
so as to provide individual
The management of bipolar disorder should be based upon a robust therapeutic relationship.
Psychological strategies are effective and should be regarded alongside pharmacological treatmentsas integral to the management of bipolar disorder.
The clinical practice recommendations (CPR) for bipolar disorders should be used in conjunctionwith other recognised sources to guide the management of bipolar disorder.
Practice recommendations or treatment guidelines cannot fully capture the myriad of variablesunique to each individual and thus need to be used ﬂexibly alongside consideration of the person,their sociocultural context and availability of resources.
The bipolar CPR focus on the management of bipolar disorder in adults. Special populations,comorbidities and novel treatments have not been reviewed in detail.
Acta Psychiatr Scand 2009: 119 (Suppl. 439): 27–46All rights reserved
2009 John Wiley & Sons A/S