PATHOPHYSIOLOGY OF RUPTURED APPENDICITIS

Non-modifiable Modifiable
-20 yrs old  Diet: People whose diet is low in fiber and rich in
Gender: male refined carbohydrates.
(male- female =2:1)  Infections: Gastrointestinal infections such as
Amebiasis, Bacterial Gastroenteritis, Mumps

Episodes of
constipation

Obstruction of the appendix by

(fecalith (hardened stool), lymph
node, tumor, foreign objects)

Increase in pressure inside the

appendix lumen that result to
distention of appendix

Impaired venous return causing

hyperemia (improper O2, and nutrient
supply) Normal bacteria found in
appendix begin to invade (infect) the
lining of the wall

Inflammatory Response – body response
to the bacterial invasion in the wall of
appendix. Increased Immune complex
causes swelling of tissue resulting to
inflammation of appendix
S/S: abdominal pain, fever, and increase
swelling of appendix. Vomiting and loss of
appetite

Appendectomy

inflammation and infection spread Pain- located @ RLQ, causing

through the wall of the appendix causing Guarding, Vomiting & loss of appetite
death of tissue.
Tissue Trauma
The appendix ruptures due

Perforation (formation of a hole in an organ),

Disruption of cell fecal materials exits to peritoneal cavity
membrane causing formation of abscesses
(periappendiceal abscess).Infection can
spread throughout the abdomen (peritoneal
cavity

Starts of inflammatory
process Bacterial invasion of Peritoneal Cavity Sepsis (the condition or syndrome
causing inflammation of the membrane caused by the presence of
microorganisms or their toxins in the
that lines the abdomen peritoneum tissue or the bloodstream ) --
(Peritonitis) Septicemia
S/S: swelling of the abdomen, severe - It can be treated through antibiotic and
Release of pain, and weight loss fluid replacement
prostaglandin/
bradykinin

Pain in surgical site Activity intolerance Recovery