Schematic Diagram

Pathophysiology (Book-based) COPD and Tuberculosis

Non- Modifiable Factors Modifiable Factors

Age Environment

Sex Work

Genetic Predisposition Smoking

Primary Infection

Inhalation m. tuberculae Impaired lung clearance

Bronchial inflammatory airway obstruction

Infecting tuberculae bacilli
phagocytosed
Carried into regional broncho pulmonary lymnodes
Alveolar hypoventilation

Necrotic degeneration Weakened disruption

Cavities filled with cheese mucus and dead blood cell

Collapse of small airways in expiration

Drain into trcheobronchial tree

Chronic bronchitis emphysema