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P. 1
Practical Blood Pressure[1] (1)

Practical Blood Pressure[1] (1)

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Published by Fadzil Abu Bakar

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Published by: Fadzil Abu Bakar on Jan 27, 2012
Copyright:Attribution Non-commercial

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12/04/2012

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Computer simulationexperiments of effect of different autonomic drugs onarterial blood pressure & heartrate of rats
1
 
A
rterial blood pressure
A
rterial blood pressure(
ABP)
 (
ABP)
 
ABP is directly proportional to
cardiacoutput (CO
P)
& peripheral vascular resistance (
PVR)
2
COP= HR X SV
PVR
depends mainly on diameter of small sized arterioles
 
11
sTsT
experiment: effect of different dosesexperiment: effect of different dosesof of norepinephrinenorepinephrine(N
A)
on H
R
&
ABP
(N
A)
on H
R
&
ABP
3
Inject 2 , 4 & 8 nmol/kg of NA
Observation:increased ABP with minimal effect onHR, whichincreases only with high doses

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