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Pharma Bio World Feb 2012

Pharma Bio World Feb 2012

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Published by akedia1
Versatile applications of Phospholipids
Versatile applications of Phospholipids

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Published by: akedia1 on May 08, 2012
Copyright:Attribution Non-commercial

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09/08/2013

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Wearein the age ofsciencend technologyandwecannotlivewithoutt. There s awealth of sciencennaturalaterialsotyetcompletelynderstoodrutilised.aturalroductscanyieldmaterialswondedulor health ndnutritionrovidingurefor manyof thelifestylediseases.oday'srbanlifestyleand oodhabitshas madehumaneingvictimovariousomplexdiseasesueodeficiecyof esse*tial *utrie*tsin the body.These eryess€fitiialutrients:come,fromnature.
hospholipidsreessentialoleculesthatplayital olesn health ndareound n cellularembranes.
Acelln hehumanody annotunctionnormallyithouthepresencefthesephospholipids.s the namemplies,phospholipidsremadef he ombinationofipidsfats)nd hemineralhosphorusboundoapolareadroupike holine.Theseipidsreundamentalomponentsofhe ellmembraneshichre ssentialforgrowth,aturingndroperunctioningof cells. hushospholipidsreprimebuildinglocksf ife.Phospholipidsixtureslecithin)ereamonghe irstealthoods, ndmoresophistlcatedreparationsave mergedsversatileutraceuticalsndunctionaloodconstituents.ietaryhospholipidsntakehas eclined,ainlyueo ncreasedoodrefiningndprocessingyadministeringphospholipidst ispossibleomprovemembraneunctionsssociatedithmembraneroteinsndipids.here reevidencesrom linicaltudieshat hownumberfcases fmetabolicmbalancesthat an ecured y ntakefspecialolarlipidsndhospholipidsAlthoughresentnmanyoods, aturalphospholipidsrefound nhigherconcentrationsn soy,eggs,marinesourcesndhebrainissue f animals.Phospholipidsre lsohemost utritionallyimportantonstituentsfsoyaecithin.Naturaloya-PhospholipidsSoyaPhospholipidsreegardedsversatilend unctionalngredientsoffood. heyrenaturallyccurringcomplexixturefphospholipidsfsoya.hemainhospholipidsresentinsoyaecithinrePhosphatidylcholine(PC), hosphatidylethanolaminePE),phosphatidylinositolPl)nd hosphatidicAcidPA).hese reproduceds aco-producturingoyabeanilefining,sterilised ndstandardised.ixedphospholipidsnpowderedrgranulatedformroducedyde-oilingaturaloyaphospholipids,re sed rallyinceanyyears.ithheEC egulationsnEuropeN0NGM0CertifiedPphospholipidsrendemandromheoodupplementndustryin he nterestf he onsumers.PowderedecithinLECIVA-S25P)susedmainlyor heproductionf foodsupplementsn heorm f ablets,ardgelatinapsulesr nutritionalremixes.GranularecithinLECIVA-S25G)as lsoorovedo beaneffectivend onvenient form f administrationroundheworldformanyearsincet can econsumeddirectlysa supplementr sprinkledon salads.health laim asbeenformulatedorde-oiledecithinmixedphospholipids):De-oiledoy ecithinayelpomaintaina healthy holesterolevel rom oodsprovidingg/day.SoyahosphatidylcholinePhosphatidylcholineroducedy solventfractionationfnaturaloya hospholipidsusingoodgradeolventsndgreenchemistryechniques,asbeen sedsuccessfullyo treativerdiseasessupportedymultipleouble-blindrials.Phosphatidylcholinesalsonaturalipid
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Pharma Bio World
Februory012> 41
 
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UfiihtheEcregulationsinEuropeNoNGMocertifiedPphospholipidsrein demandromthefoodsupplement!ndustryn theinterestofthe
consum.er.s;
:..plasmaholineevel yoraldministrationofPhosphatidylcholinen capsulertonicorms.oyaPhosphatidylcholine(LECIVA-S35)s anaturalrecursorofcholinendhusfthesynthesisftheneurotransmittercetylcholinenincreasedateofsynthesissgenerallyassociatedithnmprovementfmemoryandmuscleunction.In 1998,henstitutefMedicinelOM)ofheUSNationalcademyfSciencesidentifiedholinesanessentialutrientandecommendedailyntakemounts.Andn 2001,heUSFoodndDrugAdministrationFDA) pprovednutrientcontentlaimorcholine,nablingoodmanufacturersoinformheironsumersvia heoodabel.TheecommendedveragentakeAl)foradultss550mg/dayfcholineormennd425mgldayorwomen.holinein thedietouldeavailablesreecholinerbounds estersuchasglycerophosphocholine,phingomyelin,rphosphatidylcholine.lsonEuropeealthClaimsaveeenormulatedspeciallyorPhosphatidylcholine:.SoyaPhosphatidylcholineupportslivermetabolismndmayhelPdetoxificationromfoodsproviding1.2glday..SoyaPhosPhatidYlcholineelPsmaintaininghealthyholesterolevelfromoodsroviding.2gldaY.ThebioavailabilityfPhosphatidylcholineis excellentnds suitableoraisinghecholineeveln blood.raldministrationofCholinealtsasundesirableideeffectshichmayevenncreaseheseverityfexistingiveramages.Phosphatidylcholinessafeoakeithoutanyproblems,lson combinationithotherutrientsvenueothegoodcomoonentflecithinhicherformsfunctionsncholesteroleductionndiverhealth,hemostrequentf thesereacutendchronicirrhosisf theiver'fatty egenerationf heiversteatosis,fattyiver)ndiveramageromlcohol,hydrocarbons,edicinestc.ln casesfPreviousiverdamagePhosphatidylcholineasboughtboutamarkedmprovementnthespeedfrecoveryyepairinghecellmembrane,renewalrregenerationfLiverparenchymaTheeneficialffectfPhosphatidylcholineonheiversconnectedithtsole sacentraluildinglockn heellmembrane.Phosphatidylcholines hemostbundantphospholipidsfcellmembranes,hereforethemostmportantuildinglockormakingeplacementfmembraneass'Phosphatidylcholinemulsifiesndreaksdownatdepositsn thebodY,hichmakethelpfuln thepreventionfgallstones,iherosclerosis,eartisease,andiverroblems.esearchashownihatPhosphatidylcholines beneficialndepression,emoryossndeurologicaldisorders.t is threeimesmoreotentthanecithin.eurologicalisordersrisingfromdeficiencyfheneurotransmitteracetylcholineanereatedyncreasingheemulsifyingropertiesmprovingheadsorptionfotherutrientsdministeredwitht.Phosphatidylcholineas xceptionalemulsifyingroperties,nwhichheiverdrawsoproducehedigestiveileluid.TheungandntestinaliningellsusePhosphatidylcholineomakehesurfactantoatingsssentialo theirasandluidxchangeunctions.ndPCsthepredominantuildinglockorhecirculatingipoproteins.Cs safendwelloleratedelleyondeveralrams'dailyntake.NaturalhospholipidsnrichedithPhosphatidylcholinereavailablesliquidrwaxyproductsuitableorformulations.iquidhosphatidylcholine(LECIVA-35)susedmainlynsofielatincapsules,hereasaxymaterialsikeLECIVA-S50ndLECIVA-S70anbeusedorpharmaceuticalsriposomaldrugeliveryystems.heseroductsmayalsoaveotentialpplicationsnnasalpraysornterstitialungisease(Pulmonaryibrosis).EggPhospholiPidsIn additiono significantlyigherontentofPhosphatidylcholine,gghospholipidsprovideggproteinshichrehemostbalancedndompleteetofaminocidsfoundn naturendoftenmissingromotherroteinources.IPOVA-E100sanaturalixturefeggphospholipidsndproteinsroducedyextractionfeggolk,isaatandholesterolreeowderuitableforabletsrhardhellncapsulationandandealutritionalidorgrowingchildren/teenagersndsportsmenithneedsorproteinupplements.owever,thisproductsnotsuitableorpeople
42lFebruory2012
PharmaBioWorld
Logonto www.phormobioworld.com

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