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    Summary of Nick Lane's Transformer
    Summary of Nick Lane's Transformer
    Summary of Nick Lane's Transformer
    Ebook46 pages43 minutes

    Summary of Nick Lane's Transformer

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    #1 Frederick Hopkins, President of the Royal Society, was a major advocate for biochemistry as a scientific discipline separate from chemistry. He was also a major advocate for the use of biochemical processes to accelerate cell division.

    #2 Frederick Hopkins, President of the Royal Society, was a major advocate for biochemistry as a scientific discipline separate from chemistry. He was also a major advocate for the use of biochemical processes to accelerate cell division.

    #3 Hans Krebs, the German-Jewish scientist, fled to Britain in 1933 and invented the manometer, which measured the pressure of gases. He then went on to study respiration, which he considered the most pressing biological question of his time.

    #4 The harder the discoveries, the better the stories. The more scope they have to colour our thinking.

    LanguageEnglish
    PublisherIRB Media
    Release dateSep 6, 2022
    ISBN9798350000405
    Summary of Nick Lane's Transformer
    Author

    IRB Media

    With IRB books, you can get the key takeaways and analysis of a book in 15 minutes. We read every chapter, identify the key takeaways and analyze them for your convenience.

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      Book preview

      Summary of Nick Lane's Transformer - IRB Media

      Insights on Nick Lane's Transformer

      Contents

      Insights from Chapter 1

      Insights from Chapter 2

      Insights from Chapter 3

      Insights from Chapter 4

      Insights from Chapter 5

      Insights from Chapter 6

      Insights from Chapter 1

      #1

      Sir Frederick Gowland Hopkins, the president of the Royal Society of London, was a sprightly 71 years old in 1932. He had begun his address with a celebration of nuclear physics. He was an unabashed advocate for his fledgling field of biochemistry.

      #2

      Sir Frederick Hopkins was a brilliant and meticulous chemist who had been expelled for truancy from the City of London School. He took several short courses at which he excelled before finally getting a break in forensic medicine at Guy’s Hospital in London.

      #3

      The most pressing question in biology at the time was how respiration works. Respiration burns food in oxygen to generate the energy we need to live. But not all the energy is released as heat immediately. Some is first captured and used to drive work, before it is eventually dissipated as heat.

      #4

      The energy released by the reaction was captured and used to drive everything that life does. The way in which this happened was unknown, however. It was discovered that respiration takes place in the mitochondria, the powerhouses of the cell.

      #5

      The key method that Warburg had pioneered was to measure the escape of gases from thin slices of tissue, cut using a razor blade. When practiced skilfully, the slice was thin enough for oxygen to penetrate fully by diffusion. The slices were then placed in a solution with a similar composition to blood plasma, and gases could bubble out of the tissue slice.

      #6

      The experiment for which Warburg won the Nobel Prize in 1931 was just so beautiful that I have to tell you about it. Warburg knew he could block respiration by using the gas carbon monoxide, which in cells binds to metal atoms in the catalyst that converts oxygen to water.

      #7

      The most amazing thing about Krebs’s experiment was that he was able to modify Warburg’s methods for measuring gases emanating from tissue slices to piece together most of these missing steps.

      #8

      Krebs was interested in the breakdown of amino

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