ILOILO DOCTORS’ COLLEGE

COLLEGE OF NURSING
West Avenue, Molo, Iloilo City

DRUG STUDY (HYPERTHYROIDISM

Drug Name Classification Indications and Side Effects Special Nursing

and Contraindications and Adverse Precautions Responsibilities
Mechanism of Effects
Action
Generic Classification: Indications: Side Effects: Avoid contact  Observe 12
Name: Antithyroid Used for treating Nausea and sports or other rights in
Methimazole hyperthyroidism in vomiting, situations giving
patients with diarrhea, where medications
Trade/ graves’ disease or cramps, bruising or  Instruct
Brand toxic multinodular tremors, injury could patient to take
Name: goiter. nervousness, occur. the drug with
Tapazole insomnia, meals to
headache, Do not have decrease
Dosage: and weight any gastrointestina
10mg loss immunizations l symptoms.
(vaccinations)  Advise patient
Route: without about the
PO Actions: Contraindications Adverse doctor’s effects of
Increases : Effects: approval. iodine and its
metabolic rate, Patients with Tachycardia, Antithyroid presence in
Frequency cardiac output Thyrotoxicosis, hypertension, agents may iodized salt.
and Timing and protein myocardial and lower the shellfish and
Q6H 12-6- synthesis. infarction and palpitations body's OTC cough
12-6 Useful for severe renal disease resistance and medicines
treating there is a  Emphasize the
thyrotoxic chance the importance of
crisis and in patient might drug
preparation for get the compliance;
subtotal infection the abruptly
thyroidectomy. immunization stopping the
is meant to antithyroid
prevent. drug could
bring on a
thyroid crisis
 Teach patient
the s/sx of
hypothyroidis
m: lethargy,
puffy eyelids
and face, thick
tongue, slow
speech with
hoarseness,
lack of
perspiration
and slow
pulse.
 ILOILO DOCTORS’ COLLEGE
COLLEGE OF NURSING
West Avenue, Molo, Iloilo City

DRUG STUDY (HYPERTHYROIDISM

Drug Name Classification Indications and Side Effects Special Nursing
and Contraindications and Adverse Precaution Responsibilities
Mechanism of Effects s
Action
Generic Classification Indications: Side Effects: May cause  Observe 12
Name: : Used if Stomach pain, drowsiness. rights in
Propylthiouraci Antithyroid methimazole or headache, Caution giving
l radioactive iodine drowsiness, patient to medication
treatment is vertigo, itching, avoid s
Trade/ Brand contraindicated or rash, hives, joint driving or  Give with
Name: as an alternative pain and other meals.
Propycil treatment option in swelling, fever, activities  Watch for
a patient with changes in taste, requiring hypothyroi
Dosage: Grave’s disease or nausea and alertness dism
100mg toxic multinodular vomiting until (mental
goiter. response to depression,
Route: medication cold
PO It is a preferred is known. intolerance,
antithyroid drug in fatigue and
the first trimester of Use hard non
Frequency and pregnancy. cautiously pitting
Timing with edema)
Q8H 8-4-12 Contraindications Adverse lactation  Monitor
Actions: : Effects: CBC
Inhibits the Contraindicate to Hepatotoxicity,  Instruct to
production of those Agranulocytosis inform easy
new thyroid hypersensitive to , and Bleeding bruising or
hormone in the antithyroid drugs bleeding
thyroid gland. and pregnancy  Apply
It acts by warm or
inhibiting the cold
enzyme compress
thyroid to forehead
peroxidase, or back of
which usually neck to
converts relieve
iodide to an headache
iodine  Assist
molecule and during
incorporates ambulation
the iodine to prevent
molecule into falls
amino acid
tyrosine.
 ILOILO DOCTORS’ COLLEGE
COLLEGE OF NURSING
West Avenue, Molo, Iloilo City

DRUG STUDY (HYPERTHYROIDISM

Drug Name Classification Indications and Side Special Nursing
and Contraindications Effects and Precautions Responsibilities
Mechanism of Adverse
Action Effects
Generic Classification: Indications: Side Avoid driving  Observe 12
Name: Antithyroid Used to reduce the Effects: or hazardous rights in giving
Carbimazole formation of Itching, activities, as it medications
thyroid hormones rash, may cause  Assess vital
Trade/ in patients with headache, extreme signs regularly
Brand Hyperthyroidism. It nausea and drowsiness.  Educate the
Name: is also used to vomiting, patient about
Neomerdin restore the normal diarrhea, Temporarily the importance
function of the painful stop of medication
Dosage: thyroid before its joints, carbimazole adherence, and
60mg partial removal by feeling therapy at the advise them to
surgery. dizzy, time of radio- report any
Route: thinning iodine adverse effects
PO hair administration. promptly.
 Collaborate
Actions: Contraindications: Adverse Avoid with healthcare
Frequency Blocks thyroid Serious, pre- Effects: Carbimazole if providers to
and Timing hormonogenesis existing Acute you are adjust dosage
TID 8-1-6 by inhibiting haematological pancreatitis, pregnant or as needed and
the action of conditions such as, Swollen planning monitor
thyroid history of acute glands, pregnancy or thyroid
peroxidase, pancreatitis, and Low blood breastfeeding. function tests
organification severe hepatic sugar, low It may cross to ensure
of iodide and impairment. white blood the placenta therapeutic
their uptake by cell count and harm the efficacy.
tyrosyl radicals unborn baby.  Educate the
as well as the patient that
coupling of potential side
iodotyrosine effects and the
with importance of
iodothyronine regular follow-
residues (T3 up
and T4) which appointments
in turn suppress is crucial for
the synthesis of comprehensive
thyroid care.
hormones.