CLIENT MEDICATION FORM
Trade & Generic Names Pharmacokinetics (absorption, [onset, peak, duration], distribution, metabolism,
Albumin excretion)
Absorption: following IV administration, absorption is essentially complete.
Albuminar, albutein, buminate, normal human serum albumin,
Distribution: confined to the intravascular space, unless capillary permeability is
plasbumin increased
Metabolism and Excretion: probably degraded by the liver
Classification
Therapuetic: volume expanders
Pharmacologic: blood products, colloids
Client Order (include dosage. Frequency, & route) Side Effects
As needed CNS: headache CV: pulmonary edema, fluid overload, hypertension, hypotension,
MAR rate: 10ml/ per minute tachycardia
Total volume: 500 GI: increased salivation, nausea, vomiting
Use within 4 hours of opening Derm: rash, urticaria MS: back pain Misc: chills, fever, flushing
Obtain from lab
Contraindication
Allergic reactions to albumin. Severe anemia. CHF. Normal or increased
Recommended Dosage Range intravascular volume. Use cautiously in severe hepatic or renal disease;
Hypoproteinemia- 25% Albumin dehydration
IV adults: 50-75 g Drug Interactions
Shock- 5% Albumin None significant
IV adults: 500 ml may be repeated within 30 minutes
Uses/Indications (individualize for client) Nursing Implications (including client teaching)
Expansion of plasma volume and maintenance of cardiac output in situations Monitor VS’s, CVP, and intake and output before and frequently throughout
associated with fluid volume deficit, including shock, hemorrhage, and burns. therapy. If fever, tachycardia, or hypotension occurs, stop infusion and notify
Temporary replacement of albumin in diseases associated with low levels of physician immediately. Antihistamines may be required to suppress this
plasma proteins, such as nephritic syndrome or end-stage liver disease, resulting hypersensitivity response. Hypotension may also result from infusing too rapidly.
in relief of reduction of associated edema. May be given without regard to patient’s blood group.
Assess for sings of vascular overload during and after administration.
Mechanism of Action Infusions of normal serum albumin may cause false elevation of alkaline
Provides colloidal oncotic pressure, which serves to mobilize fluid from phosphatase levels.
extravascular tissues back into the intravascular space. Requires concurrent Patient Family Teaching:
administration of appropriate crystalloid. Therapuetic effects: Increase in Explain the purpose of this solution to the patient
intravascular fluid volume. Instruct patient to report signs and symptoms of hypersensitivity reaction.