Colonoscopy Overview
Definition
Colonoscopy is an endoscopic procedure that allows direct visualization and examination of
the entire colon and distal part of the terminal ileum using a flexible fiber-optic or video
endoscope inserted through the rectum.
Types of Colonoscopy
1. Diagnostic Colonoscopy:
o Performed to investigate gastrointestinal symptoms or abnormalities.
2. Therapeutic Colonoscopy:
o Includes interventions such as polypectomy, biopsy, hemostasis, stent
placement, or dilation of strictures.
3. Screening Colonoscopy:
o Used in asymptomatic individuals, typically for colorectal cancer
screening (especially in adults aged ≥45-50).
4. Surveillance Colonoscopy:
o Follow-up in patients with previous colorectal cancer, polyps, or IBD.
Common Indications
1. Diagnostic:
o Lower GI bleeding (melena, hematochezia)
o Change in bowel habits (constipation, diarrhea)
o Unexplained iron deficiency anemia
o Chronic abdominal pain
o Suspected IBD or colorectal cancer
2. Screening/Surveillance:
o Age-based colorectal cancer screening
o Personal/family history of colorectal polyps or cancer
o Surveillance in IBD (Crohn’s or Ulcerative Colitis)
3. Therapeutic:
o Polypectomy
o Hemostasis of bleeding lesions
o Foreign body removal
o Stent placement (e.g., obstructive colorectal cancer)
Contraindications
Absolute Contraindications:
• Suspected or confirmed perforation of the colon
• Fulminant colitis/toxic megacolon (e.g., severe UC flare)
• Peritonitis
• Acute myocardial infarction or unstable cardiopulmonary status
Relative Contraindications:
• Poor bowel preparation
• Recent colonic surgery
• Severe coagulopathy or anticoagulation (unless reversible)
• Severe diverticulitis
• Pregnancy (depends on indication and gestational age)
Potential Complications
Early (During or within 24h):
• Perforation (0.1–0.2%)
• Bleeding (especially post-polypectomy)
• Cardiorespiratory events (due to sedation – hypoxia, hypotension, arrhythmias)
• Infection (rare)
• Abdominal pain or distention due to air insufflation
Late (After 24h to several days):
• Delayed bleeding (especially after polypectomy or biopsy)
• Post-polypectomy syndrome: transmural burn without perforation causing
pain, fever, leukocytosis
• Bowel obstruction (rare, usually due to stricture formation or edema)
• Infection/sepsis (e.g., from bacteremia in high-risk patients)
Preparation & Sedation
• Bowel preparation: polyethylene glycol or sodium phosphate the day before
• Sedation: usually conscious sedation (e.g., midazolam + fentanyl), sometimes
deep sedation or general anesthesia
• Consent: discuss risks, benefits, and alternatives