LisaScan EM

Automated Microplate Reader

For Immunology and Microbiology

SERVICE MANUAL

Revision:
Erba Lachema s.r.o., Karásek 2219/1d, 621 00 Brno, CZ LisaScan EM/SM/31082023
 Service Manual

Automated Microplate Reader

For
Immunology and Microbiology

Document Version: 2017.01

Last Updated: February 28, 2017

Service Manual LisaScan EM

Foreword
This manual is organized in a progressive sequence for easy study and reference. It is an
instructional aide to provide a reference for easy servicing and maintenance of the
analyzer. It contains detailed description of the analyzer features, specifications, PCB
layouts, wiring diagrams, trouble shooting and replacement procedures.

Use of this manual along with proper training will ensure better serviceability,
maintenance, and trouble free analyzer operation with optimum performance.

Before servicing the analyzer, service engineer should:

1. Read and understand this manual.

2. Be trained by authorized person.

3. Be familiar with the operation of the analyzer.

NOTE: Keep this manual in an easily accessible place.

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Service Manual LisaScan EM

Legal Information
All rights are reserved by manufacturer of this product.

Manufacturer is the copyright owner of this document.

The contents of this document are subject to change without prior notice and without legal
obligation.

This document and the information herein are provided for the sole use of the intended
recipient(s) and for information purposes only.

This document contains contents which are the confidential and proprietary information of
the manufacturer.

This document cannot be modified, reproduced, translated or transmitted in any form or

by any means for any purpose, without prior written permission from the manufacturer.

No part of this document can be copied or reprinted, in whole or in part, without prior
written permission from the manufacturer.

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CONTENTS
1. OVERVIEW OF ANALYZER ........................................................................................ 1-1
1.1. INTRODUCTION ............................................................................................... 1-1
1.2. ANALYZER VIEW ............................................................................................. 1-2
2. SAFETY........................................................................................................................ 2-1
3. ANALYZER FEATURES .............................................................................................. 3-1
3.1. HARDWARE SPECIFICATIONS ....................................................................... 3-1
3.2. SOFTWARE SPECIFICATIONS ....................................................................... 3-3
3.3. KEYBOARD DESCRIPTION ............................................................................. 3-4
4. INSTALLATION ........................................................................................................... 4-1
4.1. INSPECTION .................................................................................................... 4-1
4.2. UNPACKING ..................................................................................................... 4-1
4.3. INSTALLATION REQUIREMENTS ................................................................... 4-2
4.4. ELECTRICAL REQUIREMENTS ...................................................................... 4-2
4.5. INSTALLATION PROCEDURE ......................................................................... 4-2
4.6. PRINTER HOUSING AND PRINTER PAPER INSTALLATION......................... 4-3
4.6.1. INTERNAL PRINTER INSTALLATION ..................................................................... 4-3
4.7. COM PORT SETTINGS .................................................................................... 4-3
4.8. USB Driver Installation ...................................................................................... 4-4
5. BLOCK DIAGRAM ....................................................................................................... 5-1
6. FUNCTIONAL DESCRIPTION OF PCB ....................................................................... 6-1
6.1. POWER SUPPLY SECTION ............................................................................. 6-3
6.2. CONTROL LOGIC SECTION (Not used with Cortex) ....................................... 6-7
6.2.1. CONVERSION OF ANALOG TO DIGITAL SIGNALS ............................................... 6-9
6.3. MOTOR CONTROL AND MEMORY ............................................................... 6-12
6.4. PHOTOMETRIC UNIT (ELE12001R3) ............................................................ 6-15
6.5. USB PCB ELLC2003R6 (Not used with Cortex) .............................................. 6-17
6.6. USB AND HOST DEVICE SCHEMATIC (Cortex) ........................................... 6-20
6.7. JUNCTION PCB (ELE12004R5 / ELE12004R7.1) .......................................... 6-21
6.8. EXTENDER PCB (ELE12011R0) .................................................................... 6-23
6.9. PRINTER......................................................................................................... 6-24
6.10. KEYPAD AND DISPLAY SECTION .............................................................. 6-24
7. TESTING AND CALIBRATION .................................................................................... 7-1
7.1. TESTING OF SMPS ADAPTER ........................................................................ 7-1
7.2. TESTING OF MAINBOARD .............................................................................. 7-1
7.3. POWER ON HARDWARE TEST ...................................................................... 7-1
7.4. SYSTEM SETUP ............................................................................................... 7-3
7.4.1. LAB INFORMATION................................................................................................. 7-4
7.4.2. SETTING THE TIME ................................................................................................ 7-4
7.4.3. SETTING THE DATE ............................................................................................... 7-5
7.4.4. SETTING THE DATA OUTPUT MODE .................................................................... 7-6
7.4.5. MIXING .................................................................................................................... 7-8
7.4.6. Lamp Saver .............................................................................................................. 7-8
7.5. ADJUSTING LCD DISPLAY BRIGHTNESS ...................................................... 7-9
7.6. PHOTOMETER CALIBRATION ........................................................................ 7-9

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7.7. SELECTING THERMAL PRINTER ................................................................. 7-12

7.8. MULTILINGUAL OPTION ................................................................................ 7-12
7.9. MEASURE VOLTAGE ENTRY ........................................................................ 7-12
8. PROGRAMMING PROCEDURES ............................................................................... 8-1
8.1. Cortex CPU Board (ELE12005R3 / ELE12005R4) Programming ...................... 8-1
8.1.1. Pre-requisite ............................................................................................................. 8-1
8.1.2. Programming Procedure........................................................................................... 8-1
8.2. Software Upgrading for Cortex CPU Board ..................................................... 8-10
8.2.1. Pre-requisite ........................................................................................................... 8-10
8.2.2. IAP Programming Procedure .................................................................................. 8-11
9. SERVICE CHECK ........................................................................................................ 9-1
9.1. VOLTAGES ....................................................................................................... 9-2
9.2. PLATE SETTINGS ............................................................................................ 9-2
9.3. PHOTOMETER ................................................................................................. 9-3
9.4. KEYBOARD TEST ............................................................................................ 9-4
9.5. PRINTER CHECK ............................................................................................. 9-5
9.6. DOWNLOAD PARAMS ..................................................................................... 9-5
10. PC INTERFACE THROUGH ELI-LIMS. ................................................................... 10-1
11. MAINTENANCE AND ANALYZER CARE ............................................................... 11-1
11.1. CHECKS PRIOR TO LAMP REPLACEMENT ............................................... 11-1
11.2. LAMP REPLACEMENT PROCEDURE ......................................................... 11-1
11.3. REPLACEMENT OF THE PAPER ROLL ...................................................... 11-5
11.4. PROCEDURE FOR REFITTING THE ROLLER IN WINSPU MECHANISM ... 11-8
11.5. MAINTENANCE SCHEDULE ............................................................................. 11-1
11.6. PHOTOMETER LENS CLEANING .................................................................... 11-2
12. TROUBLE SHOOTING GUIDE ................................................................................ 12-1
13. WIRING DIAGRAM .................................................................................................. 13-1
14. SPARE PARTS LIST................................................................................................ 14-1
15. ASSEMBLY DRAWINGS AND SPARE PARTS LIST ............................................. 15-1
15.1. BASE PLATE ASSEMBLY ............................................................................ 15-1
15.2. SLIDE BASE PLATE ASSEMBLY ................................................................. 15-3
15.3. CABINET ASSEMBLY ................................................................................... 15-5
15.4. FIBER OPTICS ASSEMBLY ......................................................................... 15-7
15.5. LAMP / FILTER ASSEMBLY ......................................................................... 15-8
15.6. CARRIER DRIVE ASSEMBLY .................................................................... 15-10
16. APPENDIX ............................................................................................................... 16-1
16.1. REVISION HISTORY .................................................................................... 16-1

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1. OVERVIEW OF ANALYZER
1.1. INTRODUCTION
The LisaScan EM is an 8-channel Micro well plate reader for Quantitative,
Qualitative and Semi Quantitative (mixture of both) determination of wide range of
analytes in body fluids.
Unique features of the analyzer are:
⚫ It is a 96 well micro plate reader with a large built-in graphic LCD display
and Thermal Printer.
⚫ Operation is through a non-tactile keyboard with quick shift from one
function to another without going through complex sequential operations.
⚫ It is provided with memory of 100 programmable tests and 5000 well’s (52
plates) results.
⚫ The analyzer is provided with a 320x240 dots liquid crystal display with
having alphanumeric and graphic capabilities.
⚫ User can take a Printout of Collated Report by Date wise or ID wise or both
by Date & ID wise or Test wise or Plate ID wise or by both Plate ID & Date
wise and ID wise with Demographic.
The software is complete with the device diagnostics self-test function capable of
providing timely flag / error messages related to Test results or analyzer
malfunctioning.

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1.2. ANALYZER VIEW

TRAY COVER THERMAL PRINTER

DISPLAY KEYBOARD LEGEND

RUN TEST LED INDICATOR

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PARALLEL PORT FOR

SERIAL NO. PLATE
EXTERNAL PRINTER

EXTERNAL
USB PORT FOR PC
KEYBOARD(PS2)
COMMUNICATION
CONNECTOR

POWER SUPPLY INPUT DC JACK ON/OFF SWITCH

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2. SAFETY
This section provides safety information about analyzer. Use this product properly
and safely to prevent injuries and or damage to property. User must read these
safety precautions before installation/use and follow the directions.
⚫ Only qualified personnel should use the analyzer.
⚫ While operating, maintaining, servicing or repairing the analyzer, follow all the
procedures described in this manual.
⚫ Always ensure that mains switch is OFF while connecting or removing or
servicing the analyzer.
⚫ Observe all WARNINGS and CAUTIONS posted on the system or described in
this manual.
⚫ Avoid contact with all electrical circuits of analyzer; observe CAUTIONS posted
on the analyzer.
⚫ Never use substitute parts on the analyzer or modify it in any way.
⚫ Keep the analyzer out of the rain and any other water splash. Pay attention to
inclination, vibration, shock etc.
⚫ During the operation photometric lamp becomes extremely hot. DO NOT look
directly into the light path of the lamp when it is ON. DO NOT touch the lamp
when it is ON.
⚫ If the lamp needs to be changed, always switch off the lamp by switching off
the analyzer and then wait for minimum 10-min/until lamp has cooled down.
⚫ Avoid using dangerous flammable material around the analyzer. Fire or
explosion may be caused by ignition.
⚫ Avoid areas that are adversely affected by atmospheric pressure, temperature,
humidity, ventilation, sunlight, dust and air containing salt, sulfur, etc.
⚫ Take necessary precautions against hazards associated with the use of clinical
laboratory chemicals. Specific recommendations for each reagent used with the
analyzer are normally found on the manufacturer’s package inserts or on
product information sheets for each chemical. Wipe up any reagent spillage on
the analyzer immediately.
⚫ Pay attention not to exceed time and volume necessary for diagnosis. Keep
monitoring the behavior of whole system in order to detect any malfunction.
⚫ Take immediate corrective measures including shutdown of operation when
any malfunction is detected in the analyzer.
⚫ In the event of trouble, do not play with the analyzer and leave any repair work
to an authorized expert.

Caution: NEVER OPERATE ON A WET OR DAMP SURFACE.

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3. ANALYZER FEATURES
3.1. HARDWARE SPECIFICATIONS
1 SYSTEM TYPE Open system
2 MEASUREMENT Vertical photometry
PRINCIPLE
3 SETUP Bench top.
4 PLATE TYPES 96 well micro plates
User Selectable well mapping
5 WELLS TYPE Flat wells
U wells
6 OPERATING MODE Absorbance
Quantitative
Qualitative
Semi-quantitative
Kinetic mode
7 MEASUREMENT MODES Continuous
Step
8 SHAKING MODES Three Linear Speeds - Low, Medium and Fast
9 WAVELENGTH SELECTION Monochromatic (Single)
Bichromatic (Dual)
Four Filters (Quad) available only in READ Absorbance
mode
10 CALCULATION MODES Non-linear Standard
Cut-off
Index Formula
Column Subtraction
Cubic Spline
Point to Point
Linear Regression
Linear – Log
Blank, Control, Assay Validation equations with facility of
accurate flagging.
Multi-standard calibration as well as cut-off equation
programmable in the same test.
11 BLANK OPTIONS Blank, Control, Assay Validation equations Against Air /
Water, Well, Plate, Column, Column Mean, Row, Row
Mean.
12 NUMBER OF Up to 10 standards
PROGRAMMABLE Storage / display / printing of multi standard curves and
STANDARDS cut-off equations for all parameters.

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13 100 TOTALLY “OPEN” TEST Selectable through keypad. Parameters can be viewed /
PROGRAMS changed / printed and permanently deleted / stored. All
positions can be open for qualitative as well as
quantitative assays or mixed.
14 PHOTOMETER Optical system 8 VERTICAL measurement channels with
8 photodiode array, using Fiber optics cable for light
transmission.
Maximum six Filters
Standard Four filters – 405 nm, 450 nm, 492 nm, 630 nm
Two filters optional – 578nm and 700nm
Light Source: 13.8V/50W Quartz Halogen Lamp.
Photometric Resolution : 0.001OD
Wavelength Range : 400 to 750 nm
Measurement Range : (0 to 3 OD)
Accuracy :
0.0 ~ 3.0 OD/492 nm: better than ±5%
Linearity : 400 to 750 nm - VIS model:
0.0 ~ 2.0 OD/492 better than ±1 %
2.0 ~ 3.0 OD/492 better than ±1.5 %
Precision :
0.0 ~ 2.0 OD/492 nm: better than 5% CV
2.0 ~ 3.0 OD/492 nm: better than 5% CV
15 READ MODE NORMAL : 17 Seconds
SPEED : 8 Seconds (for single wavelength)
16 DISPLAY(Monochrome) High resolution Graphics LCD 320x240 pixels, LED
Backlight, View area: 120x92 mm
18 KEYBOARD Rugged waterproof & membrane panel
19 PC COMMUNICATION USB communication.
Protocol compatible with Eli-LIMS and TNW.
20 PRINTER INTERFACE Built in High resolution, 384 dots per line, thermal printer
type having full graphics facility.
21 COMPUTER INTERFACING Windows Based Software with data management
SOFTWARE (OPTIONAL) capabilities to store patient results, store/display
calibration curve /QC curves.
22 PATIENT REPORT Report generation for last (5000) Sample’s is
viewed/printed/stored.
Lab name in Print-out
Lab name in Display
Collated reports
Print-out of Normal Range along with the result (on
external printer only).
Sorted by:
Date
I.D.
Both by Date and I.D.
Test

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Plate ID
Both by Plate ID and Date
23 ONLINE HELP At each step on-line help in each menu. Beeps and online
instructions on erroneous entry.
24 OPERATING 20 – 40 °C
TEMPERATURE
25 STORAGE TEMPERATURE -10 to + 50 °C.
26 HUMIDITY Max.80% RH, non-condensing.
27 MAINS SUPPLY 16 V - 24.5 V DC using External Auto ranging SMPS
adapter.
115/230VAC ±10%, 50/60Hz., Max. 90 Watt. (CE & UL
certified)
28 SIZE: 502 X 369 X 216mm
29 WEIGHT: 7Kg
30 CE Certification IEC 61010-1/EN 61010-1
NOTE:
Above specifications subject to change without prior notice

3.2. SOFTWARE SPECIFICATIONS

1. Following analytical modes of operation are available:
a. Absorbance
b. Qualitative
c. Quantitative
d. Semi quantitative
e. Kinetic
2. 100 totally “OPEN” test programs selectable through keyboard.
3. Parameters can be viewed, edited, printed and deleted.
4. Report: Report generation for last 5000 samples are stored and obtained
by
a. Date
b. I.D.
c. Both by date and I.D.
d. Test wise
e. Plate ID wise
f. Plate ID and Date wise
5. Graphic presentation of Non Linear calibration curves.

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6. Provision to run at least 5 external controls with each test.

7. Non-linear calibration (10 standards).First standard is zero standard.
8. Monochromatic as well as bichromatic measurements possible.
9. On-line help.
10. Self-diagnostics.
11. Help messages on erroneous entry.
NOTE: Above specifications are subject to change without prior notice.
Screens shown in this manual are meant for demonstration purpose and may
differ from actual.

3.3. KEYBOARD DESCRIPTION

KEY DESCRIPTION
These are multifunctional keys. Each key is used for
entering a number seen on the key and up to three
alphabets in upper and lower case .E.g. The numeric key
<1> is used to enter/select an alphabet or the number in
the following sequence 1, A, B, C, a, b, c following each
press.
Decimal point is used to enter the concentration and
absorbance value in calibration table. It is also used to
enter appropriate value in cutoff equations for qualitative
assays.

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Negative sign is used to enter the absorbance value in

calibration table. It is also used for cutoff equations for
qualitative assays.

▪ Paper feed key is used to Advance the paper when

new paper roll is inserted.
▪ It also used to advance the paper whenever printing
is functional.

This key is used to reset the instrument without resetting

the memory. Reset key is not active while test Run is in
progress. But it is active while editing the parameters for
the test.

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4. INSTALLATION
4.1. INSPECTION
The analyzer is tested before shipment and is packed carefully to prevent any
shipping damage. It is user’s responsibility to inspect all cartons upon arrival and
notify the carrier for any apparent damage. Follow the steps described in the
paragraphs below to install the analyzer.

4.2. UNPACKING
The main unit and accessories like power adapter, power cord is packed in single
cartons. The representative is responsible for unpacking, installing and initial
setting up of the analyzer.
Following is the list.
Serial Item
Description Quantity
Number Code
POWER CORD WITH TYPE D / MTYPE PLUG & C5 TYPE
1 116117 CONNECTOR. LENGTH 1.5 METERS 1 NO.
(ONLY FOR DOMESTIC)
POWER CORD WITH TYPE E / F TYPE PLUG & C5 TYPE
2 116118 CONNECTOR. LENGTH 1.5 METERS 1 NO.
(ONLY FOR EXPORT)
3 101508 ALLEN KEY WHITE BIT HEX BALL SIZE: 1.5 MM 1 NO.
4 101510 ALLEN KEY WHITE BIT HEX BALL SIZE: 2.5 MM 1 NO.
5 101511 ALLEN KEY WHITE BIT HEX BALL SIZE: 3.0 MM 1 NO.
6 103217 DUST COVER 1 NO.
7 110309 THERMAL PAPER ROLL FOR PRINTER (57mm X 30 M) 1 NO.
8 115981 POWER ADAPTER AC (O/P : 19.5 VDC ; 90 W) 1 NO.
OPERATOR MANUAL FOR LISASCAN EM (EXPORT) 1 NO.
9 --
OPERATOR MANUAL FOR LISASCAN EM (DOMESTIC)
104891 EliLIMS SOFTWARE KIT FOR LISASCAN EM 1 NO.
CABLE ASSEMBLY OF USB JUMPER USBC-AM-BM-B-B- 1 NO.
1 101421
S-2/USB2.0 AM/BM-1.8M 33-2 x 0160-101
2 150664 "TBM-Eli-LIMS" HASP SRM basic dongle 1 NO.
3 -- Eli-LIMS SOFTWARE – CD 1 NO.
NOTE: Please refer to dispatch note for detailed checklist. ***

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4.3. INSTALLATION REQUIREMENTS

The proper location is an important consideration; a poor location can lead to
malfunction of the analyzer. Please follow our environmental and electrical
suggestions to ensure the accuracy and precision of the analyzer and to maintain
high level of safety for your personnel.
Since the analyzer is comparatively smaller, it can be comfortably accommodated
on any standard sized table.
Remember that a minimum 30cm space is maintained between the Rear, Left
panel and the wall to allow for heat dissipation.
PROBLEMS resulting from the relocation of the analyzer done by
unauthorized service representative are not covered under warranty.

4.4. ELECTRICAL REQUIREMENTS

Voltage and Single phase continuous stabilized AC 230/115 volts ±10%, 50 / 60
Frequency Hz.
Grounding Perfect earthing must be provided at power source with all applicable
local requirement (A grounded, power plug only should be used. The
voltage between earth and neutral should not exceed 5 V).
Plug Points 3 Nos. of 5 Amps sockets should be available near the mounting
desks. (Normally only one socket is required per analyzer and 2 extra
sockets are recommended for using any measuring equipment and
engineering tool if required while servicing.) Failure to properly
ground the analyzer bypasses important safety features and may
result in an electrical hazard. Heavy duty electrical devices like Air-
conditioners, Refrigerators, Oven, Centrifuge etc., should not be
operated on the same electrical lines as the analyzer.

4.5. INSTALLATION PROCEDURE

1. Unpack the analyzer and other accessories from the box.
2. Check for any physical damage. In case of any damage, report it to your
local branch immediately. If everything is found OK then, continue to step 3.
3. The Analyzer is equipped with an external AC power adapter (also referred
as SMPS) and the power cord for the External AC adapter.
4. Proper use of the appropriate power cord assures adequate grounding for
the system. Failure to properly ground the analyzer bypasses important
Safety features and may result in an electrical hazard.
5. Connect the power cord of the external SMPS to the mains socket & check
the output of the SMPS, it should be ± 0.5 V range.
6. Put the output end of the Power cord in the socket provided at the rear of
the instrument.
7. Switch ON the mains supply and then switch ON the instrument by ON/OFF
switch provided on the SMPS.

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4.6. PRINTER HOUSING AND PRINTER PAPER

INSTALLATION
4.6.1. INTERNAL PRINTER INSTALLATION
The thermal printer is housed inside the chassis. It is an extremely low noise
printer. When an improper installation (printer lever is not pressed downward) of
paper is detected, an audible alarm in the form of beeps is sounded and the
message “-TP-” is displayed on the screen.
Warning: BEFORE REMOVING THE COVER, SWICTH OF THE
POWER SUPPLY.

Refer below Figure 1 for proper routing of Thermal Printer Paper roll.

NOTE: The thermal paper used must match the specification of the original one,
since the calibration of the working temperature is optimized for that kind of paper.
Failure to use proper quality of paper may permanently damage the printer.

Caution: DO NOT TOUCH THE PRINTER PAPER CUTTER.

For details refer section 11.3 REPLACEMENT OF THE PAPER ROLL

4.7. COM PORT SETTINGS

The COM Port settings for the PC connectivity through HyperTerminal software
are:
a. Baud rate 9600 bps
b. Data Bits 8
c. Parity None
d. Stop Bits 1
e. Flow control None

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4.8. USB Driver Installation

Install the USB driver from provided CD, follow the below steps-
1. Start the driver installation Setup program

2. Click Next

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3. Click Next

4. Select Install

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5. Select ‘Launch the CP210xVCP Driver installer’ and click ‘Finish’

6. Select ‘Install’

7. Select ‘OK’

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8. Connect the USB Cable between PC port & Analyzer’s USB port.

9. Close all applications. Right click on ‘My Computer’ -> ‘Properties’. ->
‘Hardware’ -> ‘Device manager’

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10. Check the ‘Ports’(COM & LPT), Silicon Labs CP210x USB to UART
Bridge’ to be listed

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5. BLOCK DIAGRAM
Mains AC I/p
(115/230Vac)

USB A & B port

SMPS
(18Vdc, 90W) LCD Display
ASP LED
Dc-Dc distribution T.S. Controller
Pcb
5Vcc – Logic, Motor-1
Display
Motor-2
Analog supply for ADC
CPU board
Vp – Printer head PS CNTL
12VL– Lamp Lamp
Fan
±5Va PS
18V motor, fan

Thermal Photometer Box

Printer

The major blocks of the analyzer consist of Main board, thermal printer,
photometer, Keypad, liquid crystal display (LCD) and DB9 serial connector for PC
communication. Keypad and thermal printer is interfaced to main board using a
junction PCB along with three OPTO each for Filter wheel, Tray Home & Tray (no
longer used in cortex PCB). There are two stepper motors; one is for Filter wheel
(Unidirectional) & other one for Tray (Bidirectional) Movement.
The LCD is a 320x240 dots backlight display with alphanumeric and graphic
capabilities which enables the user to read in case of less ambient light. This is
most sensitive device to get damaged, which require careful handling.
DB9 serial connector is to transmit data/Result from Analyzer to PC. It is Serial to
USB convertor.
Photometer is a device to measure the intensity or power of a beam of light. Light
from the lamp passes through the sample kept in the flowcell. Some amount of
light is absorbed by the sample while the rest is transmitted. The photometer
measures this transmitted light and provides the digital measurement to the
microcontroller. Based on this, the microcontroller performs set of calculation to
derive the result. The analyzer can serve 4 different filters (wavelengths), with the
option of adding 2 more additional filters.
Main board as the name suggests is the heart of the analyzer, which controls all
the hardware/software functions of the analyzer. Refer the details of main board in
chapter 6.

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6. FUNCTIONAL DESCRIPTION OF PCB

MAIN BOARD
As shown in block diagram of analyzer, main board is the heart of this analyzer.
This main board gives necessary commands and controls the operation of other
peripheral such as Keyboard, LCD, Printer and Photometer. Major blocks are
explained below.
Main Board Block
320 * 240
3V3 volt. LCD 0‐7 Graphics LCD
+5Vcc
Regulator
CS,WR,RD,CD,RST

TFT DISPLAY
R 0‐5; G 0‐5; B 0‐5 640X480 Dots
Ext. (PS2) Keyboard CLK, DATA RGB

VS; HS; DE; U/D;

TCP/IP Vp
Ethernet
Thermal
RXD, TXD
Printer

SDRAM
DATA 0‐15 & ADD 0‐
Memory
FLASH
DATA 0‐15 & ADD 2‐
Memory
SDMMC CARD
SD 0‐3, CLK, CD, CMD

Motor Driver IC Moto

DIR, ENB, CLK r1

+18VDC
MAIN
CONTROLLER Motor Driver IC Moto
Photo‐Meter PCB DIR, ENB, CLK r2
+/‐5Va
8 Photo‐Diodes
with Op Amps

USB Printer
D+, D‐ Port (Host)
MUX USB PC
3‐8 line Mux selection lines D+, D‐ Port (Device)

Serial
SI, CLK, CS, SO, INT
ADC

Matrix Key Pad

GPIO
3V RTC Supply

Other Sensors, ASP

GPIO LED
Touch Screen (Opto, Fan)
Controller SI, CLK, RST, SO,

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COMPONENT LAYOUT (ELP72001R8)

OR

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COMPONENT LAYOUT OF CORTEX CPU PCB (ELE12005R4)

6.1. POWER SUPPLY SECTION

Instrument can be operated at 115/230 V AC ±10% auto ranging power supply
with the use of AC to DC adaptor which gives 18 V/ 24 V DC required as input for
the internal devices.
This instrument uses three power supply sections designed to provide power to
electronic circuit, lamp & photometer and the thermal printer.

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Power Supply > External Power Adaptor provides 18V/24V output and is given as
input to the analyzer. This 18V/24V DC supply is further converted to +5V DC,
+12V DC and, +5V DC isolated supply by main board power section, and its
outputs are:
1. + 5 V DC for microcontroller and logic and for Thermal printer power supply.
2. + 13.5 V DC for the Halogen lamp (adjust supply by trimpot) and cooling
fan.
3. ± 5 V DC isolated supply for photometer PCB and ADC section.
4. +18 V DC to motor directly derived from the mains supply of 18 V / 24 V DC
from adaptor.

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SCHEMATIC - POWER SUPPLY SECTION

OR

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SCHEMATIC - POWER SUPPLY SECTION (CORTEX)

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Any defect in the section will lead to any of the following problem(s)
1. Lamp voltage fluctuation.
2. Lamp not ON.
3. Printer not working.
4. Backlight of LCD is OFF.
5. Analyzer is not getting switched ON.
Action to be taken
1. Replace Main Board.

6.2. CONTROL LOGIC SECTION (Not used with Cortex)

The operations for controlling the instrument are performed by the Main Board.
This section is provided with ST10F276 microcontroller and 89V51RD2
microcontroller, 64K of EEPROMs. Also a timer, a serial interface RS 232C, and a
24 bit parallel interface are present on the card itself. The logic is all in CMOS
technology to guarantee low consumption and high reliability. The RTC is provided
with inbuilt battery.

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Any defect in the section will lead to any of the following problem(s)
1. Communication is not taking place between processor and peripheral
devices.
2. External printer is not working.
3. Calibration data, Patient report etc. are is not getting stored.
Action to be taken
1. Replace Main Board.

6.2.1. CONVERSION OF ANALOG TO DIGITAL SIGNALS

This section of the main board selects one among different analog signals at a time,
such as input voltage, lamp voltage, VCC and photometer reading etc. converts these
signals into digital equivalent number. This number is further processed by controller.
The CS5460 performs the control of the measurement operations. It contains a 24-bit
A/D converter, the reference voltage, and the necessary I/O ports for talking with the
microcontroller, as well as the serial interface to the outside.
Any defect in the section will lead to any of the following problem(s)
1. In Service check of analyzer not displaying numeric values.
Action to be taken
⚫ Replace main board.

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SCHEMATIC – ANALOG TO DIGITAL CONVERSION SECTION

OR

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6.3. MOTOR CONTROL AND MEMORY

This section controls the motion of motor using IC L6208. It is a DMOS Fully
Integrated Stepper Motor driver features a non-dissipative over current protection
on the high side Power MOSFETs and thermal realized in Multi-power-BCD
technology. It includes a constant off time PWM current controller. When the
voltage drop across the sense resistor becomes greater than the voltage at the
reference input (VREFA or VREFB) the sense comparator triggers the mono stable
switching the motor off. When mono stable times out, the motor will again turn on.
To store different types of data IC three 64 K bytes IC 24c512 are used. IC U4 is
used for user changeable chemistry parameters and values of standards and blank
for non-linear chemistry, U5 is for patient reports and U6 is used for default
chemistry parameters.
IC 12c887 is a Real Time Clock plus RAM. Its function includes to update date and
time. The date, time and memory are maintained even in the absence of power
with the help of inbuilt battery.

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SCHEMATIC – MOTOR CONTROL AND MEMORY SECTION

OR

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Any defect in the section will lead to any of the following problem(s)
1. Filter Wheel Motor is not running or not stopping.
2. Tray Motor is not running or not stopping.
3. Chemistry parameters are not stored.
4. Patient report data is not stored.
5. Date and time is not correct.
Action to be taken
1. For defect no.1 replace U14.
2. For defect no 2 replace U11.
3. For defect no.3 replace U5.
4. For defect no.4 replace U5.
5. For defect no.5 replace U3

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6.4. PHOTOMETRIC UNIT (ELE12001R3)

It is one of the major blocks of the instrument & it contains 4 different narrowband
optical interference filters of wavelengths 405, 450, 492 & 630 nm for specific
chemistry tests. Apart from these 2 optional filters of wavelength 578 and 700 can
also be provided.
The Ray of white light from the lamp is passed through a filter and then is split
through fiber optics. It passes vertically through 8 channels simultaneously.
This filtered light is detected by photodiodes which is amplified and send to the
multiplexer CD 4051 which selects one signal for A/D conversion. The digital
output is communicated to processor for further processing.
COMPONENT LAYOUT (ELE12001R3)

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SCHEMATIC – PHOTOMETRIC UNIT

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Any defect in the section will lead to any of the following problem(s)
1. Absorbance value not displayed or not displayed correctly.
Action to be taken
1. Check alignment of fiber optics.
2. Gain calibration.
3. Dark Offset.
4. Photometer PCB alignment.
5. Replace Photometer PCB.

6.5. USB PCB ELLC2003R6 (Not used with Cortex)

USB PCB having USB ‘A’ type connection for external USB printer (selected
models only). USB ‘B’ type connection for PC communication. IC CP2102 is used
to convert the serial data (Result) being dumped by the microcontroller to the PC in
USB format.
Any defect in the section will lead to any of the following problem(s):
1. USB printer not printing instrument chemistry test results.
2. Communication between PC and USB not established.
Action to be taken:
⚫ Check USB A-B cable and if found faulty, replace with new.
⚫ Check CP2102 driver in PC.
⚫ Check software communication settings in PC.
⚫ Replace USB PCB assembly.

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USB PCB COMPONENT LAYOUT

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USB PCB SCHEMATIC DIAGRAM

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6.6. USB AND HOST DEVICE SCHEMATIC (Cortex)

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6.7. JUNCTION PCB (ELE12004R5 / ELE12004R7.1)

It is the basic interface between the keyboard and CPU PCB assembly for passing
the key press signals. It also passes the data to the display assembly and thermal
printer signals. Opto signals for Tray movement, Tray Home Position & Filter wheel
Home & Filter wheel movement are conveyed through Junction PCB. Tray Motor
signals are conveyed through this PCB.
NOTE: This component is not used / required for Cortex PCB.
COMPONENT LAYOUT

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SCHEMATIC - JUNCTION PCB

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6.8. EXTENDER PCB (ELE12011R0)

NOTE: This PCB is used with the latest Cortex CPU PCB assembly.
It is the basic interface between the non-tactile keyboard and CPU PCB assembly
for passing the key press signals.

Any defect in the section will lead to any of the following problem(s)
1. Keypad is not working.
2. Thermal Printer is not working.
3. Read LED in Run Mode is not working
4. LCD display is not working/blank.
5. Home, Tray or filter wheel Opto is not working.
6. Tray Motor is not working.
Action to be taken
1. For defect 1, extender PCB connector and CPU PCB connector J37 is firmly
connected.
2. For defect 2, check if the connector J9 & J42 are firmly connected.
3. For defect 3, check if the connector J19 is firmly connected.
4. For defect 4, check if the connector J13 & J23 is firmly connected.

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5. For defect 5, check if the connector J4 & J2 is firmly connected.

6. For defect 6, check if the connector J20 & J22 is firmly connected.

6.9. PRINTER
The printer is 384 dots column graphic printer, able to give a very high printing
quality, high speed and a considerable noiselessness on thermal paper without
having to move the printing head.

6.10. KEYPAD AND DISPLAY SECTION

The liquid crystal display of 320x240 dots with alpha-numeric and graphic
capability.
A 20 key membrane non tactile keyboard is provided.

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7. TESTING AND CALIBRATION

The instrument assemblies are factory adjusted and does not require any field-
testing, adjustment or settings. It is advisable not to change setting unless
necessary.
If it is necessary, the testing, adjustment or setting must be carried out by trained
and authorized personnel only.

7.1. TESTING OF SMPS ADAPTER

1. Check the mains power supply .It should be within 90-260 V.
2. Connect one end of 3-pin power cord to the adapter and another to the 3
pin power socket.
3. Check the output of the adapter using a calibrated Multi-meter, it should not
be less than 17 V DC without load and with load it should be 18.0 – 18.30 V

7.2. TESTING OF MAINBOARD

Apply 18 VDC supply at J11 connector and measure voltages at various test points
with respect to common ground point using a calibrated Multi-meter.
Test Point Normal Condition TP details
TP8 + 5 V (± 0.25V) VCC
TP4 + 5 V (± 0.25V) Analog supply
TP7 - 5 V (± 0.25V) Analog supply
TP13 3.3V (0.25) Analog supply
TP13 +5 V (± 0.25V) VCC printer
TP2 & TP9 +18 V (± 0.5V) VCC Main
TP10 +13.2 (± 0.3V) + Lamp Molex Voltage
TP11 +3.3V (0.25) Controller supply
TP6 0V Analog GND
NOTE: Voltage at TP7 to be checked during Printing on Thermal Printer.

7.3. POWER ON HARDWARE TEST

1. Switch ON the analyzer by pressing the ON/OFF switch provided on the
SMPS adapter.
2. After switching ‘ON’ the analyzer, ERBA MANNHEIM logo is displayed and
analyzer will do self-diagnostic i.e. it will automatically check all the
important devices and will show the status on display.
3. If all the hardware tests are OK then the following display appears during
the self-diagnostic test.

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This is routine test and will be performed every time analyzer is switched
ON.

In case of one or multiple parameters are showing NOT O.K, then the analyzer will
display message PRESS <YES> TO PROCEED, asking user to proceed by
pressing <YES> key.

If all the hardware tests are OK then the Home Screen will be displayed
automatically.

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7.4. SYSTEM SETUP

The system setup menu allows the user to set the system date, time and the data
output mode. User can enter SYSYTEM SETUP menu by pressing numeric key
<5> in Home Screen.
The “SYSTEM SETUP” screen is as follows:

The numeric keys 1, 2, 3, 4, 5 and 6 are used to select the Laboratory Information,
Set Time, Set Date, Data Output Mode, mixing speed / time and Lamp Save
respectively.
Following sections cover each of the above options in detail.

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7.4.1. LAB INFORMATION

Select the numeric <1> key to enter the LAB INFO menu. The screen displayed is
as follows (The text is only for demonstrative purpose):

Follow the instruction provided in the lower box of this screen display, for entering
the lab information.

7.4.2. SETTING THE TIME

Choose the option 2 from the System Setup menu and set time. The display
screen appears as shown below.
The cursor is positioned on the TIME field on the SYSTEM SETUP > TIME screen.
Enter an appropriate time in the format as stated below.

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HOUR: Enter an hour from 00 to 23.

MINUTE: Enter minutes from 00 to 59.
SECONDS: Enter seconds from 00 to 59.
Each entry is separated by a ‘:’ sign, which appears automatically after the entry of
the 2nd digit.
Left/Right Navigation keys are provided for entering the date and time.
After appropriate entry is made, press the SAVE key to save and return to the
System Setup screen.
Press GO BACK to quit without saving and go back to the System Setup screen.
User will be prompted if the date or time is entered wrong.
Note: If an inappropriate Time entry is made, the user will be prompted with the
message, “INVALID TIME. PLEASE ENTER AGAIN.”

7.4.3. SETTING THE DATE

The analyzer incorporates a built-in calendar function, which is maintained by a
battery, and once set, the Date and Time will be printed every time the analyzer
prints result data on the printer.
Press numeric key '3' and the following screen appears:

The cursor is positioned on the DATE field on the SYSTEM SETUP: DATE
screen. Enter an appropriate data in the following format:
DAY : Enter a day from 01 to 31
MONTH : Enter a month from 01 to 12
YEAR : The last 2 digits of any year from 00 to 99

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After appropriate entry is made, press the <fn> key to save date and return to the
System Setup screen or press < PREV > to quit without saving and return to the
System Setup screen.
Note: If an inappropriate Date entry is made, the user will be prompted with the
message, "INVALID DATE. PLEASE ENTER AGAIN.".

7.4.4. SETTING THE DATA OUTPUT MODE

Choose numeric key 4 on the SYSTEM SETUP screen to select the data output
mode.

7.4.4.1. AUTOPRINT
The auto print function can be done with either of the internal thermal printer or the
external printer. Select <YES> key against the required printer selection.

7.4.4.2. TRANSMISSION
This option is selected when the results are to be sent to the external PC. Press
<YES> for selecting this option.
RESULT TRANSMISSION
1. Connect 9 pin serial cable to the DB9 serial connector on LisaScan EM
back plate (also check that its cable inside is connected to J4 connector.)
2. Open the Terminal.exe on PC.
3. Click on 'settings' option and from that select 'communication' option.
4. Select baud rate as 9600 bps.
5. Select data bits = 8.

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6. Select stop bits = 1.

7. Select parity = none.
8. Select flow control as none.
9. Do not select parity check and carrier detect.
10. Select the appropriate COM port where DB9 serial cable is connected.
(COM1/COM2/COM3/COM4/COM6)
11. Now the terminal is ready to receive the data from LisaScan EM.
12. Power on the machine. Go to 'System Setup' menu. From that select 'data
output mode' and then select 'TRANSMISSION'.
13. When the sample is run, its result is transmitted to the terminal.

7.4.4.3. MAPPING AT PC
This option is selected, when the analyzer is to be operated through a PC
(Protocol compatible with Eli-LIMS and TNW). The commands are provided by the
PC. The test parameter menu and the plate definition menu will be inactivated.
When the user tries to access this menu, the following message is displayed:
“TEST PARAMETER MENU DEACTIVATED, AS MAPPING PC OPTION ‘YES’
SELECTED.”.
The analyzer will send only the sample absorbance data to the PC on line/off line.
<SEND> key is displayed during online result screen in READ ABSORBANCE
menu (with Mapping at PC ‘YES’/’NO’ option either selected or deselected).
<SEND ALL> key is displayed in Patient Report Menu only if Mapping at PC
option is selected.
If AUTOPRINT option is selected as YES, auto printing is possible only after run
test completion. Using <PRINT> Key user can get printout of Test Parameters,
Online Result, Offline Result according to printer option selected for Mapping AT
PC ‘NO’ option.
By default, the READ Mode at power on is ‘NORMAL’. But User can select
‘SPEED’ in SYSTEM SETUP menu.

7.4.4.4. <PRINT> KEY

<PRINT> key allows the user to get the print out of the test parameters, the On-
line and the Off-line results.

7.4.4.5. READ MODE

Every test can be run in either of the 2 modes: Normal and speed.
This selection offers a precision v/s time trade off.
By default, the READ Mode is selected as ‘NORMAL’ on every power on.

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Note: At every power on the read mode will take default value & needs to be
edited always if speed mode is required.

7.4.4.6. ZERO INITIALIZTION

If zero initialization is selected, negative absorbance value obtained for Sample,
EC (Extra Control), HC (High Control), and LC (Low Control) is rounded off to zero.
Zero Initialization does not affect value of cutoff controls, Standards & Blank.
If zero initialization is deselected, all negative values are kept unchanged.

7.4.5. MIXING
This option is used for mixing of the contents of well of the micro plate before start
of the run. Choose the mixing speed option as displayed in the help window. Press
the <TEST> key to verify the selected speed. The time required for mixing can also
be entered.

7.4.6. Lamp Saver

By selecting this option, user can select the time in minutes to switch OFF the
lamp. The range selectable is between 0 to 99 minutes. 0 means lamp saver mode
is disabled.

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Whenever the user does not perform any activity on the Home Screen for specified
lamp save time then lamp will automatically turn OFF.
When user selects to start run test, lamp takes 5 minutes warm up time before
proceeding with the run.

7.5. ADJUSTING LCD DISPLAY BRIGHTNESS

Open the Cabinet and rotate preset P3 provided on the CPU PCB to adjust the
brightness/contrast of the display.

7.6. PHOTOMETER CALIBRATION

If Hardware Check Showing “Photo Meter: NOT O.K.” :

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Gain Calibration :
1. In Home Screen, press key ‘4’ for Service Check Menu.
2. Then press key ‘3’ for Photometer Menu.
3. For 4 filter version, press key ‘6’ for filter 630nm
Gain for 630nm should be in the range of 120000 ~ 220000.
4. For Microbiology / 6 filter version, Press Key ‘6’ for filter 630nm or Press
Key ‘1’ for filter 700nm.
Compare photometer count for both 630 nm & 700 nm filters and the gain
for which ever filter is higher (630 nm or 700 nm), should be in the range of
120000 ~ 220000.
5. If it is more or less than this range.
a. Check Lamp Voltage.
i) If Lamp voltage is <13.2 ±0.3V, set it in this range.
6. Check alignment of Photometer PCB – align it using the following
procedure:
a. Switch OFF the instrument, open the cabinet and then open the
Photometer PCB cover. Remove the photometer PCB.
b. Switch ON the instrument and ensure the centers of Heat filter; Filter &
Fiber Optics sources are properly aligned.
c. Ensure Lamp voltage to be 13.2 V.
d. Go to ‘Service check’ menu. Press ‘3’ & select filter 630 by pressing ‘6’.
e. Observe the Light circles through Fiber Optics using butter/tracing
paper. Observation should be at the height of Detector PCB Mount.
Transmission Lens should be considered as a reference for further
alignment of plate and Detector Lens.
f. All circles should be of same diameter & same intensity.
g. There should not be dark spots in the circle or any other light spots
around the circle. Make it dust free or any finger impression free by
cleaning the lens with lint free cloth.
h. Now go to plate movement in step mode. Keep the plate at poison no 1.
i. Center of Light circle & center of well should match. If it does not match
Do the tray OPTO adjustment & bring light circle at the center of well.
j. Now check for all other 11 positions.
k. Ensure light circle should not be greater than well’s bottom diameter.

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l. Prepare plate with 200µl water in all 96 wells and repeat steps 9, 10 and
11 to confirm proper fitting of Lamp, Mirror, Heat Filter, Filter wheel
Assembly & Fiber Optics.
m. Fix the Detector Lens Holder and check the beam diameter w.r.t
transmission lens with help of butter/tracing paper. If optical beam is not
in line with circles of butter/tracing paper, align the detector lens holder
to make the optical beam in axis w.r.t to transmission lens. Ensure that
the photodiodes are dust free or any finger impression free by cleaning
the photodiodes with lint free cloth. Now fit the Photometer PCB and
Photometer cover.
n. Select Dark filter and ensure Dark Count is in the range of ± 750 counts.
Note the Dark count of all the channels in the following format.
Filter 630nm CH-A CH-B CH-C CH-D
CH Dark
Count

Filter 630nm CH-E CH-F CH-G CH-H

CH Dark
Count
o. Now if channel to channel difference is 20-30mv then only accept the
fiber optics otherwise reject it.
p. Ensure counts will be in descending order as 630,492,450 & 405nm. i.e.
for:
i) 405 nm all the channels will be ±15% of 12 mV ;
ii) 450 nm all the channels will be ±12% of 34 mV;
iii) 492 nm all the channels will be ±5% of 65 mV.
q. Now close the machine properly.
7. Procedure for Water and DYE TEST
a. Press key ‘1’ for ‘RUNTEST’.
b. Go to ‘READ ABSORBANCE’ in RUN TEST Menu, by pressing key ’2’.
c. Press F2, Select Wavelength (SINGLE, DUAL, and QUAD).Then Define
filter from List.
d. Press F3, Select Measurement Mode (Step, Continuous)
e. Run the plate with 200µl water.
f. Water OD should be < 0.1 ABS with new finished coated plate. Note the
Water readings in the Annexure sheet.
g. Make dilutions from water as per test protocol for all the 4 filters.
h. Get the data on Terminal after each run for each filter.

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i. Note the readings of respective dyes in Annexure sheet.

j. Plot the linearity graph for all the 4 Filters in Annexure sheet.
8. Replace the Photometer PCB.

7.7. SELECTING THERMAL PRINTER

1. Go to System Setup by pressing <5>.
2. Press key sequence <F3> <F4> <F5><F1>.
3. The screen will display three options to choose from.
4. Scroll through the options using <  > and <  > arrow keys.
5. Select the desired printer option using <SELECT> key.

7.8. MULTILINGUAL OPTION

1. Go to System Setup by pressing <5>.
2. Press key sequence <F2> <F3> <F4><F5>.
3. The screen will display the available options to choose from.
4. Scroll through the options using <  > and <  > arrow keys.
5. Select the desired language option using <SELECT> key.
NOTE: Analyzer will take some time to download and reconfigure the font.

7.9. MEASURE VOLTAGE ENTRY

1. Go to System Setup by pressing <5>.
2. Press key sequence <7> <8> <9><0>.
3. The screen will display the options Logic Voltage, Lamp Voltage and
SMPS Voltage to choose from.
4. Select the corresponding voltage to be changed by using <  > and <  >
arrow keys.
5. Enter the Measure Voltage value in XX.XX format. (Eg. 05.25 for setting
voltage at 5.25V)
6. Once complete save the changes using <SAVE> key.

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8. PROGRAMMING PROCEDURES
8.1. Cortex CPU Board (ELE12005R3 / ELE12005R4)
Programming
8.1.1. Pre-requisite
The following aids are required for programming procedure
⚫ PC with in-built serial and/or USB port facility
⚫ Flash Magic utility latest version
⚫ 2 Pin Shorting Jumper caps
⚫ A-B USB cable as shown in the figure below

Type A
To Computer

Type B
To Analyzer

8.1.2. Programming Procedure

1. Power OFF the Analyzer.
2. Open the analyzer to make CPU board (ELE12005R3/ ELE12005R4)
accessible for programming.
3. Short pins 3 to 4 and 5 to 6 of J1 using 2 pin shorting jumper cap.
See the following image for reference;

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4. Connect the serial cable to J7 (ELE12005R3/ ELE12005R4) with 3 pin

molex connector and other end to PC serial cable (Connect USB cable from
PC to the USB connector on PCB).
5. Now, power ON the Analyzer.
Open Flash Magic folder and Run ‘MCU Programmer’ Flash Magic.exe on
the connected PC.
6. Click Select… button in flash magic window as shown in the following
image to open Device Database.

7. Select LPC4357 controller from the device database (Do not select
LPC4357 Ethernet)

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8. Configure Flash Magic as per the following image.

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9. Select the appropriate serial port number which is getting connected (Either
direct serial port or serial port assigned to USB connected) to the board
from the COM Port drop-down.

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10. Click ISP on the file menu of flash magic to select Erase Flash…

11. Select Erase all Flash as shown below;

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12. After successfully erasing Flash Bank A, select Flash Bank B from the
drop-down box.

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13. Once selected, the screen appears as shown below;

14. Now erase Flash Bank B as well. Repeat Steps 10 and 11 for the same.

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15. Verify that both the banks are blank using Blank Check… command as
marked in the following image;

16. Now again select Bank A.

17. Click Browse… to open the latest version of Hex File to be programmed in
the Cortex Board.
18. The configuration after re-selecting Bank A, COM port and Hex File is
shown in the following image.
NOTE: Com Port and file location will be different for different computers.

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19. Now click Start button to program the board with the latest versioned
software.
NOTE: If an error message like “Communication Error” appears after
clicking on Start, then follow the procedure mentioned in Step 20, else skip
to Step 21.
20. If an error occurs after clicking on Start button then do not close the Flash
Magic Soft ware. Simply follow these steps;
a) Power OFF the analyzer
b) Disconnect the power cable
c) Disconnect the USB cable
d) Wait for 30 seconds
e) Reconnect power cable
f) Reconnect USB cable
g) Power On the analyzer and then
h) Go to Flash Magic and again click on Start button

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21. After the successful completion, the word FINISHED appears in green color
in the bottom left corner of the screen and the progress bar will reach to the
extreme right.

22. Power OFF the instrument.

23. Remove both Jumper caps from Berg Strip.
24. Remove the serial cable connected.
25. Power On the analyzer and verify the software number in corresponding
screen to confirm the software download.

8.2. Software Upgrading for Cortex CPU Board

8.2.1. Pre-requisite
The following aids are required for programming procedure
⚫ PC with in-built serial and/or USB port facility
⚫ Flash Magic utility latest version
⚫ A-B USB cable as shown in the figure below

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8.2.2. IAP Programming Procedure

1. Go to System Setup by pressing <5> from Main screen.
2. Now press the key sequence <F1> <F1> <F1>. This will display the
programming screen.
3. There are 2 types of system upgrades;
Option 1: ERASE ALL AND UPGRADE SYSTEM SOFTWARE
In this option the entire memory will get erased including Test Parameters,
Patient reports, QC Data and System Setup values. Once this option is
selected it will not be possible to recover any data from the memory.

Option 2: UPGRADE SYSTEM SOFTWARE

In this option the memory is kept as it is and only the software is upgraded.
All the data like Test Parameters, Patient Reports, QC Data and System
Setup values will preserved as it is.
4. If you have selected,
Option 1: On pressing<F1>, a Warning/Confirmation message is displayed
on the screen stating, THIS WILL ERASE THE ENTIRE MEMORY. Press
<YES> to proceed, however once user confirms this the entire memory will
get erased as mentioned in point 4. The analyzer then enters the
Programming Mode. Press <NO> to cancel the procedure. This will bring the
analyzer back into the main menu.

NOTE: On entering the programming mode screen through Option 1, if the

analyzer is switched OFF while this screen is displayed and again turned
ON, it will load the default parameters (System Setup and Test
Parameters), however Patient Reports and QC Data are deleted and
analyzer will work with the Firmware that is programmed into it.

Option 2: On pressing <F2>, no confirmation message appears and the

analyzer will directly enter in the Programming Mode.

NOTE: On entering the programming mode screen through Option 2, if the

analyzer is switched OFF while this screen is displayed and again turned ON,
it will not have any loss of memory and data. Analyzer will work with the
Firmware that is programmed into it.
5. Once the analyzer has entered the programming mode connect the
analyzer to PC using the A-B USB cable.
6. On the connected PC, go to Device Manager from Control Panel and click
on Ports. Note-down the Communication Port number (e.g. COM1).
7. Open Flash Magic utility by double-clicking on the icon present on the
desktop as shown below or by selecting the FlashMagic.exe from folder.

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8. Click Select… button in flash magic window to open Device Database.

9. Select LPC4357 controller from the device database (Do not select
LPC4357 Ethernet)

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10. Configure Flash Magic as per the following image. Ensure that Bank A is
selected as indicated in the image.

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11. Select the appropriate serial number which is getting connected to the
board (Communication Port assigned to USB– CP2102 which was noted in
step 7) from the COM Port drop-down.

12. Click Browse… to open the latest version of Hex File to be programmed in
the Cortex Board.
13. The configuration after re-selecting Bank A, COM port and Hex File is
shown in the following image.
NOTE: Com Port and file location will be different for different computers.

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14. Now click Start button to program the board with the latest versioned
software.
NOTE: If an error message like “Communication Error” appears after
clicking on Start, then follow the procedure mentioned in Step 16, else skip
to Step 17.
15. If an error occurs after clicking on Start button then do not close the Flash
Magic Soft ware. Simply follow these steps;
i) Power OFF the analyzer
j) Disconnect the power cable
k) Disconnect the USB cable
l) Wait for 30 seconds
m) Reconnect power cable
n) Reconnect USB cable
o) Power On the analyzer and then,
p) Go to Flash Magic and again click on Start button
16. After the successful completion, the word FINISHED appears in green color
in the bottom left corner of the screen and the progress bar will reach to the
extreme right.

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Service Manual LisaScan EM

8-16
Service Manual LisaScan EM

9. SERVICE CHECK
This menu includes 6 submenus:
1. Voltages
2. Plate settings
3. Photometer
4. Keyboard test
5. Printer check
6. Download Params

9-1
Service Manual LisaScan EM

9.1. VOLTAGES
Go to SERVICE CHECK menu by pressing numeric key <4>, in the home screen
and then press <1> numeric key to go the submenu VOLTAGES. The screen is
displayed as,

9.2. PLATE SETTINGS

Press numeric key <2> in service check menu to go to plate setting options. There
are two modes of setting. They are:
1. Step
2. Continuous
The user can define the desired option by pressing either <1> or < 2> numeric key.

9-2
Service Manual LisaScan EM

The Next key can be used to advance the plate from Home position to 12 th
position i.e. when next key is pressed the plate moves from home to 1st position.
When Next key is pressed again the plate is aligned at the second position and so
on. The position 1 to 12 denotes the strip numbers A1-A12.

9.3. PHOTOMETER
Pre-channel counts of the selected filter based on the position of the plate will be
displayed on the screen. The counts of all eight channels can be viewed on the
screen. For e.g. if numeric key <2> is pressed the filter 405 will be selected and if
plate is at second position the screen will appear as follows:

9-3
Service Manual LisaScan EM

NOTE: - When ELISA mode is selected position 1 and 5 have BLK filter; however
when instrument is in MICROBIOLOGY mode, position 1 has 700 and position 5
has 578 filters.
Printout of gains will be printed only on Thermal Printer, if and only if “Thermal
Printer Select with Print Key” is selected in system setup menu.

9.4. KEYBOARD TEST

When the keys on the legend are pressed the corresponding key symbol
disappears which is an indication that the keys are functioning properly.

9-4
Service Manual LisaScan EM

9.5. PRINTER CHECK

This check is for thermal printer and when the print key is pressed the sample
characters are printed. If the paper lever is lifted up or if paper is not loaded, the
printer gives an error. An audible alarm is sounded, along with visual error
message that is displayed on the screen.

9.6. DOWNLOAD PARAMS

The user can download the default parameters of the 100 tests by this menu.

9-5
Service Manual LisaScan EM

10. PC INTERFACE THROUGH ELI-LIMS

There is a provision to perform READ ABSORBANCE through PC by means of Eli-
LIMS software (For details refer Eli-LIMS User Manual).
In this mode, the patient entry, assay parameters, plate scheduling is done with
help of Eli-LIMS software. The command for Start Run is given by Eli-LIMS to the
instrument. Instrument performs the run and sends back the results to Eli-LIMS.
NOTE: For PC interface through Eli-LIMS,
1. Instrument needs to be in Home Screen.
2. MAPPING AT PC option needs to be selected in SYSTEM SETUP > DATA
OUTPUT mode.
3. Interface requirements (i.e. COM Port selection, Baud Rate) needs to be
fulfilled.
Results will not be stored in the instrument.

10-1
Service Manual LisaScan EM

11. MAINTENANCE AND ANALYZER CARE

Due to the use of various chemicals in the reagents, a compatible cleaning and
decontaminating fluid must be used. Consult the reagent manufacturer for
recommended fluids. Secondly, to avoid any potential shock when performing
preventive maintenance on the system, turn ‘OFF’ the power switch of the
instrument.
Though air conditioning is not a must, it is advisable to keep the instrument in a
dust free, cool atmosphere, away from direct sunlight.

11.1. CHECKS PRIOR TO LAMP REPLACEMENT

The lamp needs to be checked periodically (Quarterly) for proper gain values.
1. Software Version 2012.03 or newer
a. Microbiology / 6 filter version
If the gain values at 630/700 nm are less than 120000, it is recommended to
change the lamp.
b. 4 filter Version
If the gain values at 630 nm are less than 120000, it is recommended to
change the lamp.
2. Software Version Older than 2012.03
If the gain values at 630 nm less than 175000, it is recommended to change
the lamp.
NOTE: Normally lamp life is about 1000 hours.

11.2. LAMP REPLACEMENT PROCEDURE

Warning: THE REPLACEMENT OF LAMP ASSEMBLY SHOULD
BE PERFORMED BY THE TRAINED PERSON ONLY.

Warning: SWITCH OFF THE POWER SUPPLY BEFORE

REMOVING THE COVER AND WAIT FOR SUFFICIENT TIME
FOR THE LAMP TO COOL DOWN.
1. Open the top cover of LisaScan EM. The lamp is placed at left hand side
top corner of LisaScan EM as shown.

11-1
Service Manual LisaScan EM

2. Remove the lamp holding clamp by unscrewing the two allen key screws
using Allen Key of 2.5 mm size.

11-2
Service Manual LisaScan EM

3. Note the position in which lamp holding clamp is fixed.

4. Insert one finger below the lamp and push the lamp upwards to remove it.
Gently remove the lamp by supporting it with two fingers on top and slightly
tilting it as shown.

5. Remove the defective lamp from the ceramic connector by pulling it

outwards.

11-3
Service Manual LisaScan EM

6. Replace the defective lamp with a new one. Connect it to the ceramic
connector as shown.

7. Fix the lamp in proper position, between the lamp holding clamps. Refit the
lamp holding clamp and close the cover.
NOTE: Due to the aging effect the lamp intensity may get reduced and results
may be improper.

11-4
Service Manual LisaScan EM

11.3. REPLACEMENT OF THE PAPER ROLL

For any error, the printer displays the following text:
“-TP-“
To replace the paper roll, follow the procedure as stated below:
1. Open the Printer Cover.

2. Cut the end of the paper roll as shown below so that it is easy to slide it
under the printer roller.

3. Slide the ‘Plastic Pin’ into the new paper roll.

11-5
Service Manual LisaScan EM

4. Place the paper roll along with the Plastic Pin on the support provided in the
housing.
FOR FUJITSU PRINTER
5. Release the printer lever by pulling it upward.

6. Cut the paper in ‘V’ shape and feed this paper tongue into the slot of
the paper feeder. Smoother side should face up.

7. Close the printer lever by pressing it down and close the printer
cover.

11-6
Service Manual LisaScan EM

FOR WINSPU PRINTER

NOTE: - Unlike FUJITSU Mechanism the WINSPU Mechanism does not have a
leaver to release the roller grip from paper and has a capability to completely come
out of the assembly (Currently only one side is allowed in the mounting
arrangement) to allow the user to insert the paper
FUJITSU Mechanism

WINSPU Mechanism

8. Keep the paper (Smoother side face up) touching the roller.
9. Press [PAPER FEED] several times so that the paper now comes out

10. See if the paper is properly aligned.

11. Close the printer cover.

11-7
Service Manual LisaScan EM

11.4. PROCEDURE FOR REFITTING THE ROLLER IN

WINSPU MECHANISM
In WINSPU mechanism the rubber roller which holds and moves the paper ahead
has a capability to completely come out of the assembly (Currently only one side is
allowed in the mounting arrangement) & allows the user to insert the paper.
1. This roller can be easily replaced in its original position by pressing it
downwards in the correct position. Refer below figure

Rubber roller for

guide and hold the
paper.

Roller with possibility

of getting detached
from the assembly.

2. Slide the paper below the roller and can easily fit the roller by pressing it in
correct position

11-8
Service Manual LisaScan EM

11.5. MAINTENANCE SCHEDULE

After 1000 hours

Consumables /

of operation or
Every time if
Parameters

Necessary

12 months
12 Months
possible /

6 Months
3 months
Number

Parts /
Serial

A Clean
1 External cabinet **    
2 Display **    
3 Tray surface **    
4 Lens *  
5 Lamp *  
6 Optical filters *  
Fan blades
7  
(Clean using soft hair brush)

B Check & Adjust

Tray vibration
1  
(Check & Adjust if required)
Photometer Counts
2  
(Check & Attach test print with report)
Supply Adaptor Output – 18V/24V DC
3 
(Check & report)
AC Supply L-N ~ 230VAC & N-E <
4 
5VAC (Check & report)

C Replace
1 Thermal Printer Paper 
2 Lamp 

Note:
The sign  (every time is possible/ necessary) indicates that the objet must be checked
every time a service engineer operates on the machine, because it is important to
maintain the machine in perfect working conditions
* Clean lens, filter & lamp surfaces using lint free cloth or soft tissue paper
(Allow lamp to cool)
** Clean cabinet surface & Display with wetted cloth with a no aggressive detergent
solution.
## Machine must be switched OFF for cleaning activity & verify performance after
cleaning.

11-1
Service Manual LisaScan EM

11.6. PHOTOMETER LENS CLEANING

Warning: THE PHOTOMETER LENS CLEANING SHOULD BE
PERFORMED BY THE TRAINED PERSON ONLY.

Warning: SWITCH OFF THE POWER SUPPLY BEFORE

REMOVING THE COVER.

1. Open the top cover of LisaScan EM.

2. Remove the four allen key screws of mount for Detector PCB as shown
above using allen key of 2.5 mm size.
3. Gently remove the mount for Detector PCB.

11-2
Service Manual LisaScan EM

4. Soak a lint free cloth in Isopropyl alcohol (IP) to clean the lens.

5. Clean the transmission lens as well as detector lens with the cloth soaked in
Isopropyl alcohol.

6. Wipe off any excess cleaning solution (IP) to make the lens dry and clear of
dirt/dust.
7. Refit the mount for Detector PCB and close the cover.

11-3
Service Manual LisaScan EM

12. TROUBLE SHOOTING GUIDE

Note: The Trouble Shooting of LisaScan EM must be performed only by qualified
service personnel who are familiar with the operation of the instrument.
SERIAL PROBLEM CAUSE ACTION
NUMBER
1 Instrument does 1. Mains Supply 1. Check Mains Supply
not start. 2. Power adaptor 2. Check loose connection of mains cord /
DC jack pin/cable assembly.
2 Printer does not 1. Paper 1. Reinsert printer paper. (Shiny side of
function. positioned paper should be on cutter side)
improperly. 2. Carefully remove foreign material
2. Foreign material without scratching / damaging surface
jammed in of printer.
printer 3. Press lever
3. Printer leaver 4. Check for Thermal Printer in service
open check.
4. Printer setting in 5. Insert Paper Roll
service check
5. Paper is not
present
3 Keypad not 1. Loose keypad 1. Reinsert keypad properly.
working tail 2. Go to Service Check > Keyboard Test
2. Damaged menu to check whether all keys are
keypad working.
assembly 3. Replace Keypad
4 Tray does not 1. Plate placed 1. Check placement of plate.
move improperly. 2. Clear the path of tray
2. Foreign object 3. Tighten the screws
in path of tray.
3. Retaining screw
loose in tray.
5 Tray rattles 1. Tray home 1. Properly align tray home detector Opto
detector 2. Properly align tray position detector
improperly Opto
aligned.
3. Remove and reinsert tray home/ position
2. Tray position detector Opto Cable assembly
detector
improperly
aligned.
3. Loose tray
home/ position
detector cable
assembly
6 Time and/or Time and/or date Set Time/Date in SYSTEM SETUP
date Installed for were not set at
is incorrect. initialization.

12-1
Service Manual LisaScan EM

SERIAL PROBLEM CAUSE ACTION

NUMBER
7 Time and /or Damaged clock Replace main board
date does not chip on main PCB.
display, does
not save, or is
frequently
incorrect.
8 No illumination 1. Lamp is 1. Change Lamp
of lamp inoperative. 2. Check Lamp alignment and if required,
2. Lamp / light realign properly.
path is out of
alignment.
9 Photometer Not 1. Improper Filter 1.
OK Selection a) Check filter wheel
2. Filter O/P assembly/alignment
transmission b) Check belt tension
not in range as
per chart 9.1 c) Check Opto connection
3. Lamp voltage is d) Check Opto setting/alignment
<13.2±0.3V 2. Change the old filter by new filter.
4. Lamp voltage is 3. Set it in this range.
>13.5. 4. Replace the lamp
5. Improper 5.
alignment of
Photometer a) Align it
PCB b) Replace photometer Pcb
Chart 9.1

1 If 630nm,450nm None filter count Replace 492nm filter

and 405nm should be > than
count is in range 630nm as well as
but 492nm count it should reduce
is either less proportionally from
than 450/ 405 or 630 to 405.
greater than 630
2 If all the filter o/p If all the rest Check the make of filter used and change
is not within the factors including it.
acceptance filters and output
range even is ok then only we
though lamp will get proper o/p.
voltage, optical
path including
fiber optics and
gain resistor are
OK.

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Service Manual LisaScan EM

13. WIRING DIAGRAM

13-1
Service Manual LisaScan EM

14. SPARE PARTS LIST

It is recommended that all the spares and accessories used in or along with the
equipment are critical and original, supplied by the manufacturer. In case of
requirement of these parts for trouble free working of analyzer. Kindly mention
below details while ordering spares.
SR ITEM
NO CODE DESCRIPTION QTY UOM

POWER CORD WITH TYPE D / MTYPE PLUG & C5 TYPE

1 116117 CONNECTOR. LENGTH 1.5 METERS 1 NO.
(ONLY FOR DOMESTIC)
POWER CORD WITH TYPE E / F TYPE PLUG & C5 TYPE
2 116118 CONNECTOR. LENGTH 1.5 METERS 1 NO.
(ONLY FOR EXPORT)
2 101508 ALLEN KEY WHITE BIT HEX BALL SIZE: 1.5 MM 1 NO.
3 101510 ALLEN KEY WHITE BIT HEX BALL SIZE: 2.5 MM 1 NO.
4 101511 ALLEN KEY WHITE BIT HEX BALL SIZE: 3.0 MM 1 NO.
5 103217 DUST COVER 1 NO.
6 115981 POWER ADAPTER AC (O/P : 19.5 VDC ; 90 W) 1 NO.
7 110309 THERMAL PAPER ROLL (57 MM X 30 M) FOR PRINTER 1 NO.
8 103176 PULLEY 24T IDLER ASSEMBLY 1 NO.
Drylin® N Low Profile Linear Guide Systems NS-01-17
rail,392mm length with two NW-02-17 LLY floating carriages
9 111911 and C5=20mm and C6=12mm 1 NO.
(NK-02-17-02-392-LLY)
Drylin® N Low Profile Linear Guide Systems NS-01-17
rail,392mm length with two NW-02- 17 LLYZ floating
10 111912 carriages and C5=20mm and C6=12mm 1 NO.
(NK-02-17-02-392-LLYZ).
11 100856 BEARING BALL DEEP GROOVE MR105 4 NOS
12 181602 BELT TIMING; B380MXL7.9(T-2.03 ENDLESS (IMPORTED) 1 NO.
13 181601 BELT TIMING; B100MXL 7.9(T-2.03 ENDLESS IMPORTED) 2 NOS
14 103537 NEWPORT OPTICAL FILTER 405nm 1 NO.
15 103538 NEWPORT OPTICAL FILTER 450nm 1 NO.
16 103539 NEWPORT OPTICAL FILTER 492nm 1 NO.
17 103540 NEWPORT OPTICAL FILTER 630nm 1 NO.
KEYBOARD LEGEND, MEMBRANE & CIRCUIT NON
18 103155 1 NO.
TACTILE TYPE FOR ELISA
ELECTRICAL ASSEMBLY LAMP QUARTZ HALOGEN,
19 103564 1 NO.
13.8V/50W EAELR004 R0
20 109791 ASSEMBLY CARRIER DRIVE_S 1 NO.

21 109792 BELTS FOR LISASCAN_S 1 NO.

14-1
Service Manual LisaScan EM

22 109793 IDLER PULLEY ASSEMBLY_S 1 NO.

23 109794 LAMP ASSEMBLY_S 1 NO.
24 109795 FILTER ASSEMBLY-FULL_S 1 NO.
25 109796 FILTER ASSEMBLY-BASIC_S 1 NO.
26 109797 ASSEMBLY FIBER OPTICS_S 1 NO.
27 109798 DETECTOR ASSEMBLY_S 1 NO.
ASSEMBLY PCB POS1 ELS22006/R3(Tray Opto
28 109799 1 NO.
assembly)_S
29 109800 DUCT FAN_S 1 NO.
KEYBOARD LEGEND, MEMBRANE & CIRCUIT NON
30 109801 1 NO.
TACTILE TYPE_S
PCB BARE PRINTER INTERFACE (FTP-
31 109802 1 NO.
628DSL308)(V270190 003AB)_S

32 109803 PRINTER FTP-628MCL054 FOR V2 / 5X / CH7 / V3_S 1 NO.

33 109804 ASSEMBLY JUNCTION PCB ELE12004/R5_S 1 NO.

34 109805 DISPLAY ASSEMBLY_S 1 NO.

14-2
Service Manual LisaScan EM

15. ASSEMBLY DRAWINGS AND SPARE

PARTS LIST
15.1. BASE PLATE ASSEMBLY

15-1
Service Manual LisaScan EM

BASE PLATE ASSEMBLY SPARE PARTS LIST

PART NO. CODE PART DESCRIPTION QTY./M UOM

1 103145 PLATE BASE 1 NO.
2 112796 USB MOUNT PLATE LISA 1 NO.
3 103148 MOUNT FAN 1 NO.
4 103150 DUCT FAN 1 NO.
5 103151 COVER -LAMP STRAY LIGHT 1 NO.
6 110384 HOLDER FOR CARD 1 NO.
7 110148 FOOT REST 4 NOS.
DC BRUSHLESS FAN 60 x 60 x 25 mm-
8 108619 1 NO.
KD1206PTS1 GN (Make-Sunon)
103149 SERIAL ERBA+TRANSASIA
9 1 NO.
103147 SERIAL NO PLATE FOR ERBA
CABLE ASSEMBLY EXT. KB. TO MAIN
10 103909 1 NO.
BOARD J1 CWELR015 R1
CABLE ASSEMBLY 25PIN 'D' (EXT. PRIN.) TO
11 103902 1 NO.
J6 (MAIN BD.) 20 COND CWELR007 R0

12 107721 ASSEMBLY PCB DC JACK ELP62004R5 ST 1 NO.

ASSEMBLY PCB - USB CONNECTOR

13 114499 1 NO.
ELLC2003R6
ASSEMBLY MAIN BOARD ELP72001/R8 FOR
14 108431 1 NO.
LISASCAN EM

15-2
Service Manual LisaScan EM

15.2. SLIDE BASE PLATE ASSEMBLY

15-3
Service Manual LisaScan EM

ASSEMBLY SLIDE BASE PLATE SPARE PARTS LIST

PART NO. CODE PART DESCRIPTION QTY/M UOM

1 103161 PLATE BASE SLIDE 1 NO.
2 103162 PLATE CARRIER 1 NO.
3 103163 INTERRUPTER 1 NO.
4 103164 PULLEY SHAFT REST 1 NO.
5 103165 MOUNT OPTICS OPTO 2 NOS.
6 103166 HOLDER DETECTOR LENS 1 NO.
7 103167 MOUNT DETECTOR PCB 1 NO.
8 103662 ASSEMBLY PCB PHOTOMETER ELE12001/R1 1 NO.
9 103169 LENS DETECTOR 8 NOS.
10 103170 COVER PHOTODIODE STRAY LIGHT 1 NO.
11 103172 HOLDER BELT 1 NO.
12 103173 STOPPER FOR SLIDE 4 NOS.
13 103176 PULLEY 24T IDLER ASSEMBLY 1 NO.
14 105173 ASSEMBLY PCB POS1 ELS22006/R3 2 NOS.
15 181602 BELT TIMING ; B380MXL 7.9 (T-2.03 ENDLESS) 1 NO.
(IMPORTED)
16 103180 DryLin? N Low Profile Linear Guide Systems NS- 1 NO.
01-17 rail, 392mm length with two NW-02-17 LLZ
floating carriages and C5=20mm and C6=12mm
(NK-02-17-02-392-LLZ)
17 103181 DryLin? N Low Profile Linear Guide Systems NS- 1 NO.
01-17 rail, 392mm length with two NW-02-17 fixed
carriages and C5=20mm and C6=12mm (NK-02-
17-02-392)
18 103144 ASSEMBLY CARRIER DRIVE 1 SET
19 103175 PIN LOCATING FOR TRAY 1 NO.
20 103174 PIN LOCATING 4 NOS.
21 103171 LABEL "CAUTION" 1 NO.

15-4
Service Manual LisaScan EM

15.3. CABINET ASSEMBLY

15-5
Service Manual LisaScan EM

CABINET ASSEMBLY SPARE PARTS LIST

PART NO CODE DESCRIPTION QTY/M UOM
1 103152 CABINET 1 NO.
2 103153 MOUNT PRINTER 1 NO.
3 103154 MOUNT PRINTER PCB 1 NO.
4 201237 PAPER CUTTER 1 NO.
KEYBOARD LEGEND, MEMBRANE & CIRCUIT
5 103155 NON TACTILE TYPE FOR ELISA 1 NO.

6 103156 COVER PRINTER 1 NO.

7 103157 COVER- TRAY 1 NO.
8 103158 INDICATOR LID 1 NO.
9 103159 DISPLAY SPACER 4 NOS.
10 110406 PIN PAPER ROLLER 1 NO.
11 103160 DISPLAY HOLDING PLATE 1 NO.
ASSEMBLY JUNCTION PCB ELE12004/R5 FOR
12 108432 LISASCAN EM 1 NO.
13 105651 DISPLAY ASSEMBLY 1 NO.

FUJITSU PRINTER SPARES

PRINTER FTP-628MCL054 FOR V2 / 5X / CH7 /
14 110191 V3 1 NO.
PCB BARE PRINTER INTERFACE (FTP-
15 110184 628DSL308)(V270190 003AB) 1 NO.
WINSPU PRINTER SPARES
112578 WINSPU THERMAL PRINTER HEAD: 1 NO
16 TP27FP6RZEA
112579 WINSPU THERMAL PRINTER CONTROL 1 NO
17
BOARD: TP27FX
Cable Assembly for Main Board J18 TO WINSPU 1 NO
18 113389 Printer PCB Supply CWELR030R0
Cable assembly Junction PCB J2 to WINSPU 1 NO
19 113390 Printer PCB Signal CWELR031R0
Note: - WINSPU and FUJITSU Thermal Printer Heads are interchangeable. i.e.
112578 & 110191 are interchangeable & can be used with 110184 & 112579

15-6
Service Manual LisaScan EM

15.4. FIBER OPTICS ASSEMBLY

PART NO CODE DESCRIPTION QTY/M UOM

FIBER OPTICS ASSEMBLY SPARE
109797
PARTS LIST
1 109859 8 channel Fiber Optics 1 NO.
2 103211 HOLDER FOR FIBER ASSEMBLY 1 NO.
3 103212 LENS TRANSMISSION 8 NOS.

15-7
Service Manual LisaScan EM

15.5. LAMP / FILTER ASSEMBLY

PART NO CODE DESCRIPTION QTY/M UOM

LAMP / FILTER ASSEMBLY SPARE PARTS
LIST
1 103190 SPRING LAMP 2 NOS.
2 103191 COVER LAMP 1 NO.
3 103192 MIRROR CASE 1 NO.
4 103193 BRACKET LAMP / FILTER MOUNTING 1 NO.
5 103194 HOLDER LENS APERTURE CONDENSING 1 NO.
6 103195 LENS-APERTURE CONDENSING 1 NO.
7 103196 COVER MIRROR CASE TOP 1 NO.
8 103197 MIRROR 1 NO.
9 103199 WHEEL FILTER 1 NO.
10 103200 HOLDER FOR LAMP 1 NO.
11 103201 REST FOR LAMP 1 NO.
12 103203 BRACKET FOR FILTER WHEEL 1 NO.
13 103204 PLATE FOR FILTER WHEEL MOTOR 1 NO.
14 103205 MOUNT FOR OPTO (FILTER WHEEL) 1 NO.
15 103206 SHAFT FOR FILTER WHEEL 1 NO.
16 103208 CLAMP FOR LAMP 1 NO.
17 181601 BELT TIMING; B100MXL 7.9 (T-2.03 ENDLESS) 1 NO.
18 100856 BEARING BALL DEEP GROOVE MR105 2 NOS.

15-8
Service Manual LisaScan EM

19 103564 LAMP ASSEMBLY 1 NO.

20 103187 PULLEY TIMING - T2.04 2 NOS.
21 201693 MOTOR ASSEMBLY 1 NO.
22 110145 HEAT FILTER GLASS 1 NO.
23 103207 LABEL "WARNING-HOT LAMP & OPTICS" 1 NO.

15-9
Service Manual LisaScan EM

15.6. CARRIER DRIVE ASSEMBLY

PART NO CODE DESCRIPTION QTY/M UOM

ASSEMBLY CARRIER DRIVE SPARE PARTS
109791 1 NO.
LIST
1 103182 MOTOR MOUNTING PLATE 1 NO.
2 103183 HEX SPACER - MOTOR 4 NOS.
3 103184 PLATE INTERMEDIATE 1 NO.
4 103185 SHAFT DRIVING 1 NO.
5 103187 PULLEY TIMING - T2.04 3 NOS.
6 181601 BELT TIMING ; B100MXL 7.9 (T-2.03 1 NO.
ENDLESS) (IMPORTED)
7 109663 DEEP GROOVE BALL 4 NOS.
BEARING ID5XOD10X4 ;
DDL-1050ZZ
8 201693 MOTOR ASSEMBLY 1 NO.

15-10
Service Manual LisaScan EM

16. APPENDIX
16.1. REVISION HISTORY
Revision Date Revision Description Author
2011.01 24-August-2011 First Release PP
Updated section Service check for PP
2012.01 22-Feb-2012
Voltages & Photometer
Updated Hardware & software PP
2012.02 21-July-2012 specification
Updated section Annual maintenance
2012.03 Not used --
--
2012.04
• Introduced section wise page PS
2012.05 21-March -2013 numbering
• Updated spare list
2013.01 04-July-2013 • Maintenance Schedule added PS
Following changes are updated: PS
• Functional Description of pcb
& Wiring diagram
2013.02 31-Dec-2013 • Added WINSPU mechanism
related paper loading tips &
roller refitting procedure
• Spare parts list
2014.01 -- Not used SD
2015.01 -- Not used SD
Following changes are updated: MB
• Hardware specification table
updated.
• Software Programming and
upgrade steps added for
2017.01 28-Feb-2017 Cortex.
• Spares list updated.
• Lamp Save Added
• Hidden Keys Updated

16-1
Appendix 1
 Ref.: Lisa scan
Lisa scan EM EM/ICh/31082023
INSTALLATION CHECKLIST/PROTOCOL Page: 1/2

SERIAL NUMBER: _________________________ SW VERSION: _________________________

DATE: ______________________________

LABORATORY OR INSTITUTION: __________________________________________________________

COUNTRY/ADDRESS: ___________________________________________________________________

CONTACT PERSON: ____________________________________________________________________

1. PRE-INSTALLATION
Refer to the instructions for use to:
 Check the compliance with environmental requirement
Place of installation (Building, Room, Department): ________________________________________
 Ensure customized installation of the equipment
 Check presence of all parts according to packing list
 Check Instrument and printer’s connection (if any)

UPS (type, S/N) : ______________________________________________________________

2. INSTALATION
 Installation of instrument and its external accessories.
 Connecting to mains and ELILIMS
 Instrument and software start-up
 Initial self-test
 Visual and software checking of mechanics, electronics
 System parameters setting
 Photometer gain check

3. OPERATIONAL QUALIFICATION:

3.1. KEY FUNCTIONS

 Confirm all keys function & keys functioning are smooth

3.2. VOLTAGE CHECK

 Checking and calibration of the lamp voltage _____ V
 Adapter voltage ______ V

3.3. GAIN CHECK FOR ALL FILTERS

Filter Dark 405nm 450 nm 492 nm 630nm

Gains

Range ± 750 4000 - 15000 15000 - 40000 35000 - 85000 180000 - 250000
 Ref.: Lisa scan
Lisa scan EM EM/ICh/31082023
INSTALLATION CHECKLIST/PROTOCOL Page: 2/2

3.4. HARDWARE TEST

 Check Hardware

3.5. DATE and TIME

 Check Date & time

3.6. Absorbance stability test:

Fill 100μl distilled water in the first row in the 96-well Elisa plate and perform one test in wavelength 630nm
with air as reference observed OD for all plates should <0.050 A

3.7 Precision of photometer

Run 0.5 OD plate twice and measure CV between all wells, CV should be with 5% of measured value

4. ACCEPTANCE
The installed device has been installed and successfully verified according to manufacturer’s service manual and device
meets performance specifications. This Installation protocol is evidence of execution of ERBA’s Installation at Customer´s
location and it is drawn up in 2 copies.

Following documents are integral parts to this Installation protocol at Customer:

 User manual version ______________________
 Records from tests in chapter 3.11
 The authorization certificate of service technician
 User training record

5. COMMENTS

Next preventive maintenance required: ______________________________

ERBA REPRESENTATIVE (Name, date and signature) ______________________________

LABORATORY OR INSTITUTION REPRESENTATIVE

(Name, date and signature) ______________________________
Appendix 2
 LisaScan Ref.: LisaScan/PMCh/31082023
PREVENTIVE MAINTENANCE Page: 1/2
CHECKLIST/PROTOCOL

SERIAL NUMBER: _______________________ SW/FW VERSION: __________________________

DATE: _______________________

LABORATORY OR INSTITUTION: __________________________________________________________

COUNTRY/ADDRESS: ___________________________________________________________________

CONTACT PERSON: ____________________________________________________________________

1. TYPE OF CONTROL
 After 6 months
 After 1 year
 On request
 Other _____________________________

2. SOFTWARE CHECKS
 If required, install the latest version of software ______________________

3. CONTROL POINTS

Clean lamp and check lamp voltage  Complete  Incomplete  N/A

Clean optical filter and lens  Complete  Incomplete  N/A

Clean fan assembly  Complete  Incomplete  N/A
Check and adjust tray vibration  Complete  Incomplete  N/A
Check Photometer count  Complete  Incomplete  N/A
Check the adaptor voltage  Complete  Incomplete  N/A
Replace Lamp  Complete  Incomplete If required  N/A

4. OPERATIONAL QUALIFICATION:
1. Functionality check:
 Instrument
 Initial self-test

2. Software check:
 Installed SW version is latest released SW version
 Functionality of selected commands in menu Service

3. Measurement verification:
 Check the OD / result of any of the test.
 LisaScan Ref.: LisaScan/PMCh/31082023
PREVENTIVE MAINTENANCE Page: 2/2
CHECKLIST/PROTOCOL

5. ACCEPTANCE
The installed device has been successfully verified according to manufacturer’s service manual and device meets
performance specifications. This protocol is evidence of execution of ERBA’s Preventive maintenance at Customer and it
is drawn up in 2 copies.

Following documents are integral parts to this protocol at Customer:

 User manual version ______________________
 Records from tests in chapter 5.3
 Service records (in case of any repair by an authorized service technician)
 The authorization certificate of service technician

6. COMMENTS

Next preventive maintenance required: ______________________________

ERBA REPRESENTATIVE (Name, date and signature) ______________________________

LABORATORY OR INSTITUTION REPRESENTATIVE

(Name, date and signature) ______________________________