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    The University of Texas M.D. Anderson Cancer Center launched a program to dramatically reduce deaths from eight common and difficult cancers including lung cancer, triple negative breast cancer, prostate cancer, ovarian cancer, melanoma, acute myeloid leukemia, myelodysplastic syndrome, and chronic lymphocytic leukemia. The program will examine new targeted oral therapies for lung cancer, develop personalized treatments for melanoma, establish standard screening for ovarian cancer, prevent relapse after stem cell transplant for AML, and replace chemotherapy with new oral treatments for CLL.

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    Cancer Goals 29p c

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    The University of Texas M.D. Anderson Cancer Center launched a program to dramatically reduce deaths from eight common and difficult cancers including lung cancer, triple negative breast cancer, prostate cancer, ovarian cancer, melanoma, acute myeloid leukemia, myelodysplastic syndrome, and chronic lymphocytic leukemia. The program will examine new targeted oral therapies for lung cancer, develop personalized treatments for melanoma, establish standard screening for ovarian cancer, prevent relapse after stem cell transplant for AML, and replace chemotherapy with new oral treatments for CLL.

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    4K views1 page

    Cancer Goals 29p C

    Uploaded by

    danajthom
    The University of Texas M.D. Anderson Cancer Center launched a program to dramatically reduce deaths from eight common and difficult cancers including lung cancer, triple negative breast cancer, prostate cancer, ovarian cancer, melanoma, acute myeloid leukemia, myelodysplastic syndrome, and chronic lymphocytic leukemia. The program will examine new targeted oral therapies for lung cancer, develop personalized treatments for melanoma, establish standard screening for ovarian cancer, prevent relapse after stem cell transplant for AML, and replace chemotherapy with new oral treatments for CLL.

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    of 1

    The Moon Shots Program

    The University of Texas M.D. Anderson Cancer Center launched an ambitious e ort to dramatically reduce deaths from eight common and di cult cancers. Targeted cancers, with new U.S. cases and deaths in 2012:

    Lung cancer
    1 New cases: 226,160 1 Deaths: 160,340 1 Synopsis: Chemotherapy has been the main treatment since 1970s; M.D. Anderson will examine targeted oral therapies.

    Triple negative breast cancer


    1 New cases: 68,718 1 Deaths: 11,976 1 Synopsis: Treatment remains a challenge despite great strides in treating other breast cancers. Molecular course of disease similar to ovarian cancer; treatments are converging.

    Prostate cancer
    1 New cases: 241,740 1 Deaths: 28,170 1 Synopsis: A slow-growing cancer; research will standardize criteria for when treatment is needed and distinguish a lethal cancer from a less dangerous one.

    Ovarian cancer (high-grade, serious variety)


    1 New cases: 15,596 1 Deaths: 12,750 1 Synopsis: Many patients develop resistance to drugs; high recurrence rates. M.D. Anderson primed to establish rst standard screening.

    Melanoma
    1 New cases: 81,240 1 Deaths: 12,190 1 Synopsis: One of the most aggressive forms of skin cancer, its incidence has increased over 600 percent since 1950s; leading cause of cancer death in young women. The program will include public education, sun-safety programs and develop personalized treatments.

    Acute myeloid Myelodysplastic leukemia (AML) syndrome


    1 New cases: 13,780 1 Deaths: 10,200 1 Synopsis: AML marked by diminishing returns once patient stops responding to therapy; team will work on strategies to prevent relapse after stem cell transplant. 1 New cases: Estimates from 14,000 to 45,000 1 Synopsis: A marrow disease that may be caused by exposure to carcinogens, radiation or chemotherapy. Progresses to AML in 30 percent to 50 percent of cases.

    Chronic lymphocytic leukemia (CLL)


    1 New cases: 16,060 1 Deaths: 4,580 1 Synopsis: CLL is most common adult leukemia in the U.S.; research will seek to replace chemotherapy with new oral, less toxic treatments and rebuild immune system.

    Sources: The University of Texas M.D. Anderson Cancer Center; American Cancer Society

    Houston Chronicle

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