What is the main pancreatic duct?
Duct of Wirsung
What does the Duct of Wirsung drainto?
ampulla of Vater
What is the accessory duct?
Duct of Santorini
Does the duct of Santorini drainproximal or distal to ampulla of Vater?
What type of cell make up exocrinepancreas?
These exocrine enzymes, how are they secreted?
What is pancreatitis?
inflammation of pancreas associated with injury to exocrine parenchyma
Why do we see acute pancreatitis?
biliary tract disease and alcoholism, and gallstones
How would you treat acutepancreatitis?
restrict oral intake of food; Will be supported with IV fluids, etc
What is the difference betweenchronic and acute pancreatitis?
acute is reversible and chronic is not
Cysts in kidney, liver, and pancreasfrequently co-exist in what condition?
Pancreatic Pseudocysts lack what?
a true epithelial lining
Which of the following are you morelikely to find cancer in
serous or mucinous cystadenomas - mucinous cystadenomas
What type of pancreatic cancershould be suspected if the patientdevelops metastatic fat necrosis dueto lipase release?
acinar cell carcinoma
Are intra-ductal papillary muncinousneoplasms benign orcancerous/malignant?
When digestive enzymes come down, what is the main enzyme that needs to be activated?
What activates trypsin?
What is a pancreas divisum, and what can it predispose you to?
- is the most common congenital anomaly of the pancreas- This anomaly is caused by a failure of fusion of the fetal duct systems of the dorsal and ventral pancreatic primordial
the bulk of the pancreas (formed by the dorsal pancreaticprimordium) drains through the dorsal pancreatic duct and the small-caliber minor papilla(see Fig. 19-1B).- The duct of Wirsung in persons with divisum, normally is very short (1 to 2 cm) and drainsonly a small portion of the head of the gland through the larger caliber major papilla of Vater.- Clinical significance of pancreatic divisum, the relative stenosis caused by the bulk of thepancreatic secretions passing through the minor papilla predisposes individuals to thedevelopment of chronic pancreatitis
Diagnosis of acute pancreatitis (labtests for...)
amylase (first), then lipase
What is the most common cause of chronic pancreatitis?
alcoholism/long-term alcohol abuse
Robbins Ch. 19 The Pancreas
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