• Embed Doc
  • Readcast
  • Collections
  • 1
    CommentGo Back
Download
 
CASE STUDY OF ASTHMAAsthma
is a chronic, reversible, obstructive airway disease, characterized by wheezing. Itis caused by a spasm of the bronchial tubes, or the swelling of the bronchial mucosa, after exposure to various stimuli.Asthma is the most common
chronic disease
in childhood. Most children experience their first symptoms by 5 years of age.
ETIOLOGY:
Asthma commonly results from hyperresponsiveness of the trachea and bronchi toirritants. Allergy influences both the persistence and the severity of asthma, and atopy or the genetic predisposition for the development of an IgE-mediated response to common
airborne allergens
is the most predisposing factor for the development of asthma.
CLASSIFICATION:1. Extrinsic Asthma – called Atopic/allergic asthma.
An “allergen” or an “antigen” is aforeign particle which enters the body. Our immune system over-reacts to these oftenharmless items, forming “antibodies” which are normally used to attack viruses or  bacteria. Mast cells release these antibodies as well as other chemicals to defend the body.Common irritants:
Cockroach particles
Cat hair and saliva
Dog hair and saliva
House dust mites
Mold or yeast spores
Metabisulfite, used as a preservative in many beverages and some foods
Pollen
 
2. Intrinsic asthma
– 
called non-allergic asthma
, is not allergy-related, in fact it iscaused by anything except an allergy. It may be caused by inhalation of chemicals such ascigarette smoke or cleaning agents, taking aspirin, a chest infection, stress, laughter,exercise, cold air, food preservatives or a myriad of other factors.
Smoke
Exercise
Gas, wood, coal, and kerosene heating units
 Natural gas, propane, or kerosene used as cooking fuel
Fumes
Smog
Viral
respiratory infections
Wood smoke
Weather changes
ANATOMY AND PHYSIOLOGY
:
The
upper respiratory tract
consists of the nose, sinuses, pharynx, larynx, trachea, and epiglottis.The
lower respiratory tract
consist of the bronchi, bronchioles and the lungs.The major function of the respiratory system is to deliver oxygen to arterial blood andremove carbon dioxide from venous blood, a process known as
gas exchange.
The normal gas exchange depends on three process:
Ventilation
– is movement of gases from the atmosphere into and out of thelungs. This is accomplished through the mechanical acts of 
inspiration andexpiration.
Diffusion
– is a movement of inhaled gases in the alveoli and across the alveolar capillary membrane
Perfusion
– is movement of oxygenated blood from the lungs to the tissues
.
Control of gas exchange – involves neural and chemical process
The neural system, composed of three parts located in the pons, medulla and spinal cord,coordinates respiratory rhythm and regulates the depth of respirationsThe chemical processes perform several vital functions such as:
regulating alveolar ventilation by maintaining normal blood gas tension
guarding against hypercapnia (excessive CO
2
in the blood) as well as hypoxia(reduced tissue oxygenation caused by decreased arterial oxygen [PaO
2
]. An
 
increase in arterial CO
2
(PaCO
2
) stimulates ventilation; conversely, a decrease inPaCO
2
inhibits ventilation.
helping to maintain respirations (through peripheral chemoreceptors) whenhypoxia occurs.The normal functions of respiration O
2
and CO
2
tension and chemoreceptors are similar in children and adults. however, children respond differently than adults to respiratorydisturbances; major areas of difference include:
Poor tolerance of nasal congestion, especially in infants who are obligatory nose breathers up to 4 months of age
Increased susceptibility to ear infection due to shorter, broader, and morehorizontally positioned eustachian tubes.
Increased severity or respiratory symptoms due to smaller airway diameters
A total body response to respiratory infection, with such symptoms as fever,vomiting and diarrhea.
SIGNS AND SYMPTOMS
:
1.
Non Productive to Productive Cough
2.
Dyspnea
3.
Wheezing on expiration
4.
Cyanosis
5.
Mild apprehension and restlessness
6.
Tachycardia and palpitation
7.
DiaphoresisPATHOPHYSIOLOGY:CLINICAL MANIFESTATIONS:
1.Increased respiratory rate2.Wheezing (intensifies as attack progresses)3.Cough (productive)4.Use of accessory muscles5.Distant breath sounds6.Fatigue7.Moist skin8.Anxiety and apprehension9.Dyspnea
Steps of Clinical and Diagnostic as per National Asthma Education and PreventionProgram
Mild Intermittent Asthma
of 00

Leave a Comment

You must be to leave a comment.
Submit
Characters: ...

the pathophysiology was more on signs and symptoms...

You must be to leave a comment.
Submit
Characters: ...