Cytokines are signaling molecules that are produced by immune cells to mediate and regulate immunity and inflammation. The table lists various cytokines including their source cell, target cells, and main effects. TNF and IL-1 are produced early in inflammation by macrophages and endothelial cells and target endothelial cells to increase vascular permeability and recruit leukocytes. IL-2 stimulates proliferation of T cells. IL-6 is produced by macrophages and endothelial cells and acts on the liver to induce synthesis of acute phase proteins.
Cytokines are signaling molecules that are produced by immune cells to mediate and regulate immunity and inflammation. The table lists various cytokines including their source cell, target cells, and main effects. TNF and IL-1 are produced early in inflammation by macrophages and endothelial cells and target endothelial cells to increase vascular permeability and recruit leukocytes. IL-2 stimulates proliferation of T cells. IL-6 is produced by macrophages and endothelial cells and acts on the liver to induce synthesis of acute phase proteins.
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Cytokines are signaling molecules that are produced by immune cells to mediate and regulate immunity and inflammation. The table lists various cytokines including their source cell, target cells, and main effects. TNF and IL-1 are produced early in inflammation by macrophages and endothelial cells and target endothelial cells to increase vascular permeability and recruit leukocytes. IL-2 stimulates proliferation of T cells. IL-6 is produced by macrophages and endothelial cells and acts on the liver to induce synthesis of acute phase proteins.
Copyright:
Attribution Non-Commercial (BY-NC)
Available Formats
Download as DOC, PDF, TXT or read online from Scribd
T–cell Activation in Health and Disease: Disorders of Immune Regulation Infection and Autoimmunity: Papers from an International Meeting in Oxford, UK, in September 1988