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Brand name:
Combivent
Generic name:
Ipratropium
Indication:
Maintenance therapy of reversible airway obstruction due to COPD,common colds
Drug classification:
anticholinergics, bronchodilators
Mechanism of action:
 blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle causing bronchodilation
Dosage:
Adult: 2puffs qid, Adult and children > 12yr 1 vial every 6-8 hr, Child 2-12yr 3drops/kg/dose q6-8 hrs
Special precaution:
 patients with bladder neck obstruction, prostatic hypertrophy,urinary retention, geriatric patients, pregnancy, lactation children <5 yrs old
Pregnancy risk category: BAdverse reaction: CNS:
dizziness, headache, nervousness
GI:
GI irritation nausea
Derm:
rash
CV:
hypotension, palpitations
Others:
allergic reactions, blurredvision, sore throat, epistaxis, nasal irritation
Contraindicated to:
Hypersensitivity to ipatropium, atropine, belladonna alkaloids, bromide or flurocarbons, peanut or soy allergy, avoid use during acute bronchospasm
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