O NiO100 NPs Ethanol, MW (8-10min) X=CN O R N H O + CN X + S S NiO100 NPs Ethanol, MW (8-10min) X=COOEt R S O NH R S

H N

NH2 CN O

N H

H N S

NH2

R= H, 5-Cl, 7-Cl, 5-Br, 5-NO2, 5-CH3

O N O

Scheme-1 Table 1 Synthesis of spiro and condensed indole derivatives under microwave irradiation using Ni100 nanoparticles Entry R X Time (min.)
H N S S CN O
H N S S Cl CN O
H N S S

Product
O NH2

Yield (%) NiO100/Piperidine

MP (C)

5a

CN

90/75
N H
O NH2

298

5b

5-Cl

CN

87/72
N H
O NH2

310

5c

7-Cl

CN

9
N H Cl
S S Br H N

CN O

87/74

275

O NH2

5d

5-Br

CN

88/72
CN O N H

270

H N S

O NH2

5e

5NO2

CN

10

S O2N CN O H N S S H3 C CN O
H N

90/72
N H O NH2

340

5f

5-CH3

CN

88/70
N H
O NH2

315

5g

COOEt

S O N H N O
O NH2

89/74

332

5h

5-Cl

COOEt

Cl

S O N O

87/73

288

H N

O NH2

5i

7-Cl

COOEt

10
N Cl O

88/73

226

H N

O NH2

5j

5-Br

COOEt

Br

S O N O

88/72

347

H N

O NH2

5k

5-NO2

COOEt

O2N

S O N O

84/74

265

H N

O NH2

5l

5-CH3

COOEt

10

H3C

S O N O

87/71

356