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    Pathophysiology Colonic Mass 8-01-12

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    Sheng Dela Cerna Sale
    DNA damaging agents (environmental) Chemicals Radiation Exposure to fertilizers (non-modifiable) age Sex Genetic History cell damaging agent Normal Cell Failure of DNA repair DNA Damage Mutation of the cells in the colon Alteration of genes Activation of oncogenes Inactivation of cancer suppressor genes. Hypertrophy Dysplasia colonic mucosa cell division is altered Hyperplasia Constriction of intestinal lumen in the sigmoid colon Constant awakening

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    Pathophysiology Colonic Mass 8-01-12

    Uploaded by

    Sheng Dela Cerna Sale
    48 views3 pages
    DNA damaging agents (environmental) Chemicals Radiation Exposure to fertilizers (non-modifiable) age Sex Genetic History cell damaging agent Normal Cell Failure of DNA repair DNA Damage Mutation of the cells in the colon Alteration of genes Activation of oncogenes Inactivation of cancer suppressor genes. Hypertrophy Dysplasia colonic mucosa cell division is altered Hyperplasia Constriction of intestinal lumen in the sigmoid colon Constant awakening

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    DNA damaging agents (environmental) Chemicals Radiation Exposure to fertilizers (non-modifiable) age Sex Genetic History cell damaging agent Normal Cell Failure of DNA repair DNA Damage Mutation of the cells in the colon Alteration of genes Activation of oncogenes Inactivation of cancer suppressor genes. Hypertrophy Dysplasia colonic mucosa cell division is altered Hyperplasia Constriction of intestinal lumen in the sigmoid colon Constant awakening

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    48 views3 pages

    Pathophysiology Colonic Mass 8-01-12

    Uploaded by

    Sheng Dela Cerna Sale
    DNA damaging agents (environmental) Chemicals Radiation Exposure to fertilizers (non-modifiable) age Sex Genetic History cell damaging agent Normal Cell Failure of DNA repair DNA Damage Mutation of the cells in the colon Alteration of genes Activation of oncogenes Inactivation of cancer suppressor genes. Hypertrophy Dysplasia colonic mucosa cell division is altered Hyperplasia Constriction of intestinal lumen in the sigmoid colon Constant awakening

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
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    of 3

    Modifiable: Lifestyle Nutrition Psychological Stress Acquired (Environmental DNA damaging agents) Chemicals Radiation Exposure to fertilizers

    Non-modifiable: Age Sex Genetic History

    Cell damaging agent

    Normal Cell

    Failure of DNA repair

    DNA Damage

    Mutation of the cells in the colon

    Alteration of genes

    Activation of oncogenes

    Inactivation of cancer suppressor genes

    Deactivation of proto-oncogenes

    Hypertrophy

    Dysplasia

    Colonic mucosa cell division is altered

    Metaplasia

    Hyperplasia

    Anaplasia

    Increased proliferation of colonic mucosa

    Neoplasm

    Constriction of intestinal lumen in the sigmoid colon Constant awakening from external noises, treatment and therapeutic regimen at the hospital

    Pressure around nerves in the sigmoid colon

    Acute pain

    Disturbed sleep pattern

    Activity intolerance

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