The song is based on Carnatic raga Natabhairavi - A melakarta ragam (20th)

The raga goes like this . s r2 g2 m1 p d1 n2 S / S n2 d1 p m1 g2 r2 s

This corresponds to Western Natural C Minor scale
In western notes, the raga goes like ..
C D D# F G G# A# C / C A# G# G F D# D C
B --------------------------------------1-----1------------------------------------- B
G -----------------------0--1---3-----------------3---1---0----------------------- G
D ----------0--1---3-------------------------------------------3--1---0----------- D
A ----3-----------------------------------------------------------------------3----- A
In single string:
Madai Thirandhu Paayum Nadhi Alai Naan
Manam Thirandhu Koovum Siru Kuyil Naan
B ---------1-----1---4--4--3--1------------ B
G --0--3------3-------------------31---0--- G
Isai Kalaignan

En Aasaigal

Aayiram

B 1-4---6-4--6----4--686-----6--4--6---- B
Ninaithadhu

Palithadhu

Hey

B ---1--4--6--8-----6--4--6--4----3-------------- B
Kaalam Kanindhadhu Kadhavugal Thirandhadhu
Gnaanam Vilaindhadhu Nallisai Pirandhadhu
B -88---6-8-6-4------3-4-3-1-----3-1-3--4---- B
Pudhu Raagam Padaippadhaaley

Naanum Iraivanae

B -6-6--68-------6-6--6-68--------9--9---86--8-864--- B
Vidharilum Pudharilum Swarangalin

Naattiyam

Amaippaen Naan

B -4-6-6-11--4-6-6-11--4-6-6-11----9--8--96-----36--69---8B

In multiple strings:
Madai Thirandhu Paayum Nadhi Alai Naan
Manam Thirandhu Koovum Siru Kuyil Naan
D 110. D
A 1313310......... A
E 33.. E
Isai Kalaignan

En Aasaigal

Aayiram

G 0 G
D 13131331..31.. D
A 3 A
Ninaithadhu

Palithadhu

Hey

G .0.. G
D .1..331310 D
A 3 .A
Kaalam Kanindhadhu
Kadhavugal
Gnaanam Vilaindhadhu Nallisai

Thirandhadhu
Pirandhadhu

G 000G
D 331011..001 D
A 3.3....... A
Pudhu Raagam Padaippadhaaley

Naanum Iraivanae

G ..00110..00. G
D 3.33..3.333..3..31 D
Vidharilum

Pudharilum

Swarangalin

Naattiyam

Amaippaen Naan

G 3331011..0.. G
D 133133133.3.133.......D