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The Science behind the Vitamin B12 Patch

Here is why you might not be getting your B12 with those other vitamins! When the B12 vitamin enters your body in the stomach (through food or oral pills), acids in the stomach separate the B12 from its protein source. It then must combine with intrinsic factor cells in the stomach. This B12/intrinsic factor complex travels to your intestine, where it is absorbed in the terminal ileum. The absorbed complex is then transported via blood plasma and stored in the liver. The interruption of any of these steps affects your body's ability to absorb B12.

Common B12 absorption problems As you age (over 45) or become overly reliant on acid suppressing agents like antacids, your ability to produce gastric acids in the stomach decreases, meaning that the B12 is less likely to be released from its food source. An autoimmune or other disease reduces the production or blocks the action of intrinsic factor, resulting in intestinal malabsorption. People with pernicious anemia have decreased production of intrinsic factor. Abdominal surgery reduces B12 absorption. Gastrectomy eliminates the site of intrinsic factor production. Blind loop syndrome results in competition for vitamin B12 by bacterial overgrowth in the lumen of the small intestine. Surgical resection of the ileum eliminates the site of 2

vitamin B12 absorption. Pancreatic insufficiency such as fish tapeworm infection and severe Crohn's disease affect absorption.

With the B12 Patch you can now have confidence knowing that your body is getting the B12 it needs! Not all substances are easily absorbed transdermally. A substance's ability to be absorbed is affected by its molecular stucture and molecular weight of the substance. Our extensive background in biochemistry and nutrition, along with years of study, make the Vitamin B12 Patch second to none. Studies show that blood levels of B12 increase by only 1.2% when taken orally. Each Vitamin B12 Patch is made under the strictest quality controls in the industry. All manufacturing and laboratory processes meet or exceed current good manufacturing practices. The greatest thing about the Vitamin B12 Patch is that it is so easy to use! Place the patch (size of a dime) on your neck behind your earlobe for up to 24 hours. No more swallowing large, uncomfortable pills each day or cleaning up messy powders. No more visits to the doctor for painful intramuscular B12 shots. When you take the Vitamin B12 Patch you can feel confident knowing you will get results.

How Does a Patch Work? A Patch delivers nutrients into the circulatory system by absorption through the skin. A Patch uses a special membrane to control the rate at which nutrients, contained within it, pass through the skin and into the bloodstream. For nutrients to be absorbed via the skin into the bloodstream, the drug molecules pass through the top two skin layers - the epidermis and dermis into the capillaries (small blood vessels). By direct delivery to the bloodstream, without first going to the liver (the "first-pass effect") a greater amount of the nutrients are bio-available. A Patch is designed to release the active ingredients at a consistent rate over a period of time.

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