RADANG

: - ACUT - CHRONIS

ACUT : 1. VASO DILATASI 2. PERMEABILITAS 3. EMIGRASI LEKOSIT

1. RUBOR CALOR TUMOR 2. TRANSUDASI EKSUDASI UDEMA

DOLOR

FUNGSIO LESI

EMIGRASI LEKOSIT
MARGINATION ROLLING ADHESI TRANSMIGRASI MIGRASI CHEMOTAXIS PHAGOSITOSIS : DETEKSI MENELAN MENGHANCURKAN

AKHIR PERADANGAN ACUT

RESOLUSI KOMPLIT FIBROSIS BENTUKAN ABCES RADANG KRONIS

RADANG KRONIS
1. FIBROSIS ANGIOGENESIS 2. KERUSAKAN JARINGAN 3. SEBUKAN MONOSIT : L M P PENYEBAB : 1. INFEKSI BERLANJUT 2. KONTAK BERLANJUT (EXT.AGENT) 3. AUTO IMMUN DISEASE RADANG GRANULOMATOSA JARINGAN GRANULASI SPESIFIK EPITHELOID GRANULOMA

NECROSIS

: - COAGULATIF - LIQUEFACTIVE - CASEOSA - FAT

ENZYMATIC DENATURASI DIGESTION PHAGOSITOSE KALSIFIKASI

APOPTOSIS PROGRAM CELL DEATH EMBRYOGENESIS, ORG. HORMON DEPENDENT INTEST , SKIN, LIMF

STIMULI HISTOL MECHAN TISS.RX

NEC. COAG. HIPOX.TOXIN CELL SWELL DENAT ,PROT ATP DEPLT MEMB.BREAK INFLAMATION

APOPTOSIS PHYS,PAT CHROM.CON APOP.BODY GENE ACTIV PHAGOCYTE OF.AP.BODY

SUB CELL RESPONS

LESI SITOSKELETON. LYSOSOM KATABOLISM GGN.MITOCHONDRIA. ENDOPL.RETICUL.INDUCTION. HEAT SH .PROT & PROT KIN (STRES PROT / CHAPERONINS

TROMBOSIS RESPONS
BLOOD CLOT : USEFUL HARMFUL
VASA : BESAR - KECIL ARTERI - VENA TOTAL - PARTIAL

PERAN TROMBOSIT POST MORTEM

- STREAMING BLOOD

NORMAL CONDITION : 1) ELECTRO NEG.SIALIC - ACID 2) LAMINAR FLOW 3) ENDOTHEL : PROSTACYCLIN ANTI COAGULANT ACTIVITY

EMBOLI : IKUT ALIRAN DARAH > 95% : TROMBOEMBOLISM FAT , NITROGEN GAS, FRAG TUMOR BENDA ASING , CHOLESTEROL, AMNION.

INFACT

: TOTAL OBS.ACUT LOKASI SISTEM VASE JARINGAN PEKA INFECTION OXIGEN CONTENT

RED INFARCT WHITE INFARCT