IV Vitamin C Relieves Patients with Rheumatoid Arthritis

Researchers from Riordan Clinic, namely Dr. Nina Mikirova, Dr. Joseph Casciari, Andrea Rogers, and Paula Taylor, have published a study in the Journal of Modern research in Inflammation; the study is titled "Effect of High-dose intravenous ascorbic acid on the level of inflammation in patients with rheumatoid arthritis." Researchers from Riordan Clinic have long been involved in proving that high doses of ascorbic acid can cure inflammations, cancers, atherosclerosis and other viral infections through intravenous infusions. Arthritis is a chronic rabble-rousing pain in the joints that leads to damage of the cartilage or other forms of joint damage. Some complications that may arise from extreme cases of Rheumatoid Arthritis are rheumatoid nodules, vasculitis, heart disease, lung disease, anemia and peripheral neuropathy. In order to conduct the study, the group of researchers used the following method: o Gather rheumatoid arthritis patients suffering from moderate to high levels of inflammation, and experiencing moderate to severe joint pain o The inflammation as measured by C-reactive protein levels was decreased on average by 44%. The average CRP level before treatment was 9.4 +/-4.6 mg/l, while the average after IVC therapy was 6.4+/-4.6 mg/L. Through the method, researchers infer the following results: Patients who exhibited a net CRP decrease are said to be dependent on high dose of intravenous vitamin C. based on the properties of ascorbic acid to reduce oxidative stress, decrease production of pro-inflammatory cytokines, and suppresses the activation of pro-inflammatory nuclear factors. Based on this preliminary study, researchers come up with the hypothesis that high dose intravenous vitamin C is a very important method in relieving patients with Rheumatoid Arthritis but that further studies need to be conducted. o The effect of iv vitamin therapy on patients with rheumatoid demonstrated that intravenous vitamin C therapy with dosages of 7.5g-50g can reduce inflammation and the pain levels. With high doses, Vitamin C diminishes the production of pro-inflammatory cytokines. Ascorbic acid could also be anti-oxidant which could support collagen formation and improves extracellular matrix protein synthesis.