>HUMANDNA GATAGATGGA AACGAATTAA CAATGCTACT TCGGCGGCGT GTGGACTTAA TTAAACCGGT AACCCGCAAT ATGAACCCGT ACGTTATTAT GACTTAGGGA GTGGACTTAG CCGAAAAAAG GCGTTAAAAG TTAAAACACT

CAAGCGGCGG GCGATCGAAG CGGATCGGGA AAATCGTTAG ATCTTAAAAG AACAAAGGGA GAAGCGATCA TTGAGCCATT GATAGGGTCT GCCTCAACCT GCACGTGCCA CTGGAGTGCA TCTCCTGCCT ATTTTTGTAT CTGACCTCAT CGAGACCATC GCCTGGTATG GGCGTTGAAC CTGGGCGACA ACTCTGAAAA TCACCCAGGC TTCACGCCAT CACCAGGCTA TGGTCTCGAT CAGGCGTGAG TATGAGCGTT TTTCCCTTTA CGAAATTATT CGACGTTCAT CGAAAGCGAT CGGACGGGTA TGAAACGGCG GGTTAATCTT CGGTGATCGC

TAGATAGATG AAGAAAAAGG CGGAAGCGAT ACGCGAAAAA AACCGGACTG TCGAAGAAGC TAAAAGAAGG TCAACATGCC CGGACCCGAC CGAAATTACA GGTCGATGGA AAACGAAACC AAAAAGAATT ACGACAAAGC TGTACTTCGA TGGGGCGGGA ACTCGTACTT CGGAACACCG AACAAGAACG ACGAATGCTT AAAGGTAAGT GTTTCTTACT CACTCTTTCA CCTGGGCTTC CCACGTCCAG GTGGCATGGT CAGCCTCCCG TTTTAGTAGA GATCCACCCA CTGGCTAACA GTGGTGGGCG CCGGGAGGCA GAGCGAGACT TTAAAATCCT TGGAGTGCAG TCTCCTGCCT ATTTTTTTTA CTCCTGACCT CCACCGCGCC TAAATTATTA CAGGAACCCG AGAATTCCAA CAAAGGGTAC GGACGTGTAC CCAACGGTGC GGCGATGGCG AGAACAAATG GCAAAAAATC

AGATATATAG GAACAAAGCG CAAATTAGAC AGGGGACTAC GGGGAAAGGG GAAACGGACG GTTACAAAAC GAACTTATAC GTACCGGGAA AGACCCGCGG CGAAGAAGAA GGAACCGATG AGGGAACGAC GAAAGAATTA AAAAGGGGAC AAACCGGGAA CAAAGAAGAA GACGCCGGAC GTTAGCGTAC CCAAAAAGGG GTAGGAAAAG GTTTTATTTA CCCAGGCTGA AGTGATCTTC CTAATTTTTT GTCTGCTCAC AATTGCTAAG GATGGGGTTT CCTCAACCTC CGGTGAAACT CCTGCAGTCC GAGCTTGCAG CTATCTCAAA AATCTGATTT TGGCGCGATC CAGTCTCCCG TATTTTTAGT CGTGATCCAC CGGCCCCTAA TTTCAAGAAT AAAGACGCGA TTAGCGTTAA ACGCGGAAAG CAAAAAGCGT ATGATGGCGC GACCCGGAAG CAAAAAGACC CAAAAATTAA

ATATGGAGAT TTATCGGTGG CCGCACAACC CAAAAAGCGT TACTCGCGGA TACGAAGAAG ATGGAAGCGC CAAAAATTAG TTAATCGAAC ATCATGACGA GAAATCGCGA GAAGAAGACT GCGTACAAAA GACCCGACGA TACAACAAAT GACTACCGGC AAATACAAAG GTGTTAAAAA ATCAACCCGG GACTACCCGC AATAGGGGTA ATAATGAACT AAGACAGTGG CCACCTCAGC TTTTGAGATG TGCAACCTCC ACTACAGGTG CATTATATGG CCAAAGTCCT CTGTCTCTAC CAGCTACTCG TGAGCCGAGA AAAAAAAAAG TTTTTTTTTT TCGGCTCACT AGTAGCTGGG AGAGACAGGG CCGCCTCGGC TGTGATTTTT TATGTTTTGT AATTATACTC AAGACTGCGA CGGCGGCGTT TAGACTTAGA AATACAACCG TGCAACAAAT CGCAAGCGTT TGGACGTGGG

GAGAGATTAT GGAACATCGA ACGTGTTATA ACGAAGACGG AAGCGGCGGC GGTTAAAACA GGTTAGCGGA AATCGGACCC AATTACGGAA CGTTATCGGT CGCCGCCGCC TACCGGAAAA AAAAAGACTT ACATGACGTA GCCGGGAATT AAATCGCGAA ACGCGATCCA AATGCCAACA ACTTAGCGTT AAGCGATGAA TTTTCTTGTT TGACTTTTTT CACAATCGTG CTGAGTAGCT GAGTCTGTTT GCCTCCCAGG CACGCCACTA ACCAGGCTGG GGGATTACAG TAAATAAATA GGAGGCTGAG TCGCGCCACT AAAAAAATCT TGAGATGGAG GCAAGCTTCC ACTACAGGCT TTTCACCATG CTCCCAAAGT AAGCCCAATA AGGCAGAGAA GAACCGGGCG AGAATGCATC AGAAGCGATG CTCGTCGTGC GCACGACTCG CATGTCGGAC ATCGGAACAC GTTAATCGCG

GGAACAAGTG CGACGCGTTA CTCGAACCGG GTGCAAAACG GTTAGAATTC CGAAGCGAAC ACGGAAATTC GCGGACGCGG CAAACCGTCG GTTATTAGGG GCCGCCGCCG CAAAAAACAA CGACACGGCG CATCACGAAC ATGCGAAAAA AGCGTACGCG CTTCTACAAC AGCGGAAAAA AGAAGAAAAA ACACTACACG TTCCTAATAA TTTTTTTTGA GCTCACTGCA AGGATTACAG GTCACCCAGG TTCAAGCAAT TGCCCGGCTA TCTCAAACTC GCCACTGCAT AAAAAAATTA GCAGGAGAAT GCACTCCAGC TGCCAGCAAT TCTCGCTCTG GCCTCCCGGG CCCGCCACCA TTAGCCAGGA GCTGGGATCA TTTAGATGAT AATCCTGAAC GCGTGCTACA CAATTAGAAC AAAGACTACA AAAGAAGCGG CCGGAAGACG CCGGCGATGC TTAAAAAACC ATCCGG

60 120 180 240 300 360 420 480 540 600 660 720 780 840 900 960 1020 1080 1140 1200 1260 1320 1380 1440 1500 1560 1620 1680 1740 1800 1860 1920 1980 2040 2100 2160 2220 2280 2340 2400 2460 2520 2580 2640 2700 2760 2820

proteina human_DNA 10 90 20 30 40 50 60 70

80

| | | | | | | | | GATAGATGGATAGATAGATGAGATATATAGATATGGAGATGAGAGATTATGGAACAAGTGAACGAATTAAAAGAAAAAGG GAACAAAGCGTTATCGGTGG 100

D R W I D R * D I * I W R * E I M E Q V N E L K E K G N K A L S V G 100 I D G * I D E I Y R Y G D E R L W N K * T N * K K K G T K R Y R W 100 * M D R * M R Y I D M E M R D Y G T S E R I K R K R E Q S V I G G 100 | | | | | | | | | GGAACATCGACGACGCGTTACAATGCTACTCGGAAGCGATCAAATTAGACCCGCACAACCACGTGTTATACTCGAACCGG TCGGCGGCGTACGCGAAAAA 200 N I D D A L Q C Y S E A I K L D P H N H V L Y S N R S A A Y A K K 200 G T S T T R Y N A T R K R S N * T R T T T C Y T R T G R R R T R K K 200 E H R R R V T M L L G S D Q I R P A Q P R V I L E P V G G V R E K 200 | | | | | | | | | AGGGGACTACCAAAAAGCGTACGAAGACGGGTGCAAAACGGTGGACTTAAAACCGGACTGGGGGAAAGGGTACTCGCGGA AAGCGGCGGCGTTAGAATTC 300 G D Y Q K A Y E D G C K T V D L K P D W G K G Y S R K A A A L E F 300 G T T K K R T K T G A K R W T * N R T G G K G T R G K R R R * N S 300 R G L P K S V R R R V Q N G G L K T G L G E R V L A E S G G V R I L 300 | | | | | | | | | TTAAACCGGTTCGAAGAAGCGAAACGGACGTACGAAGAAGGGTTAAAACACGAAGCGAACAACCCGCAATTAAAAGAAGG GTTACAAAACATGGAAGCGC 400 L N R F E E A K R T Y E E G L K H E A N N P Q L K E G L Q N M E A R 400 * T G S K K R N G R T K K G * N T K R T T R N * K K G Y K T W K R 400 K P V R R S E T D V R R R V K T R S E Q P A I K R R V T K H G S A 400 | | | | | | | | | GGTTAGCGGAACGGAAATTCATGAACCCGTTCAACATGCCGAACTTATACCAAAAATTAGAATCGGACCCGCGGACGCGG ACGTTATTATCGGACCCGAC 500 L A E R K F M N P F N M P N L Y Q K L E S D P R T R T L L S D P T 500 G * R N G N S * T R S T C R T Y T K N * N R T R G R G R Y Y R T R R 500 V S G T E I H E P V Q H A E L I P K I R I G P A D A D V I I G P D 500 | | | | | | | | | GTACCGGGAATTAATCGAACAATTACGGAACAAACCGTCGGACTTAGGGACGAAATTACAAGACCCGCGGATCATGACGA CGTTATCGGTGTTATTAGGG 600 Y R E L I E Q L R N K P S D L G T K L Q D P R I M T T L S V L L G 600 T G N * S N N Y G T N R R T * G R N Y K T R G S * R R Y R C Y * G 600 V P G I N R T I T E Q T V G L R D E I T R P A D H D D

V I G V I R G 600 | | | | | | | | | GTGGACTTAGGGTCGATGGACGAAGAAGAAGAAATCGCGACGCCGCCGCCGCCGCCGCCGCCGAAAAAAGAAACGAAACC GGAACCGATGGAAGAAGACT 700 V D L G S M D E E E E I A T P P P P P P P K K E T K P E P M E E D L 700 W T * G R W T K K K K S R R R R R R R R R K K K R N R N R W K K T 700 G L R V D G R R R R N R D A A A A A A A E K R N E T G T D G R R L 700 | | | | | | | | | TACCGGAAAACAAAAAACAAGCGTTAAAAGAAAAAGAATTAGGGAACGACGCGTACAAAAAAAAAGACTTCGACACGGCG TTAAAACACTACGACAAAGC 800 P E N K K Q A L K E K E L G N D A Y K K K D F D T A L K H Y D K A 800 Y R K T K N K R * K K K N * G T T R T K K K T S T R R * N T T T K R 800 T G K Q K T S V K R K R I R E R R V Q K K R L R H G V K T L R Q S 800 | | | | | | | | | GAAAGAATTAGACCCGACGAACATGACGTACATCACGAACCAAGCGGCGGTGTACTTCGAAAAAGGGGACTACAACAAAT GCCGGGAATTATGCGAAAAA 900 K E L D P T N M T Y I T N Q A A V Y F E K G D Y N K C R E L C E K 900 K N * T R R T * R T S R T K R R C T S K K G T T T N A G N Y A K K 900 E R I R P D E H D V H H E P S G G V L R K R G L Q Q M P G I M R K S 900 | | | | | | | | | GCGATCGAAGTGGGGCGGGAAAACCGGGAAGACTACCGGCAAATCGCGAAAGCGTACGCGCGGATCGGGAACTCGTACTT CAAAGAAGAAAAATACAAAG 1000 A I E V G R E N R E D Y R Q I A K A Y A R I G N S Y F K E E K Y K D 1000 R S K W G G K T G K T T G K S R K R T R G S G T R T S K K K N T K 1000 D R S G A G K P G R L P A N R E S V R A D R E L V L Q R R K I Q R 1000 | | | | | | | | | ACGCGATCCACTTCTACAACAAATCGTTAGCGGAACACCGGACGCCGGACGTGTTAAAAAAATGCCAACAAGCGGAAAAA ATCTTAAAAGAACAAGAACG 1100 A I H F Y N K S L A E H R T P D V L K K C Q Q A E K I L K E Q E R 1100 T R S T S T T N R * R N T G R R T C * K N A N K R K K S * K N K N G 1100 R D P L L Q Q I V S G T P D A G R V K K M P T S G K N L K R T R T 1100 | | | | | | | | | GTTAGCGTACATCAACCCGGACTTAGCGTTAGAAGAAAAAAACAAAGGGAACGAATGCTTCCAAAAAGGGGACTACCCGC

AAGCGATGAAACACTACACG 1200 L A Y I N P D L A L E E K N K G N E C F Q K G D Y P Q A M K H Y T 1200 * R T S T R T * R * K K K T K G T N A S K K G T T R K R * N T T R 1200 V S V H Q P G L S V R R K K Q R E R M L P K R G L P A S D E T L H G 1200 | | | | | | | | | GAAGCGATCAAAAGGTAAGTGTAGGAAAAGAATAGGGGTATTTTCTTGTTTTCCTAATAATTGAGCCATTGTTTCTTACT GTTTTATTTAATAATGAACT 1300 E A I K R * V * E K N R G I F L F S * * L S H C F L L F Y L I M N L 1300 K R S K G K C R K R I G V F S C F P N N * A I V S Y C F I * * * T 1300 S D Q K V S V G K E * G Y F L V F L I I E P L F L T V L F N N E L 1300 | | | | | | | | | TGACTTTTTTTTTTTTTTGAGATAGGGTCTCACTCTTTCACCCAGGCTGAAAGACAGTGGCACAATCGTGGCTCACTGCA GCCTCAACCTCCTGGGCTTC 1400 T F F F F * D R V S L F H P G * K T V A Q S W L T A A S T S W A S 1400 * L F F F F E I G S H S F T Q A E R Q W H N R G S L Q P Q P P G L Q 1400 D F F F F L R * G L T L S P R L K D S G T I V A H C S L N L L G F 1400 | | | | | | | | | AGTGATCTTCCCACCTCAGCCTGAGTAGCTAGGATTACAGGCACGTGCCACCACGTCCAGCTAATTTTTTTTTTGAGATG GAGTCTGTTTGTCACCCAGG 1500 V I F P P Q P E * L G L Q A R A T T S S * F F F * D G V C L S P R 1500 * S S H L S L S S * D Y R H V P P R P A N F F F E M E S V C H P G 1500 S D L P T S A * V A R I T G T C H H V Q L I F F L R W S L F V T Q A 1500 | | | | | | | | | CTGGAGTGCAGTGGCATGGTGTCTGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCG AATTGCTAAGACTACAGGTG 1600 L E C S G M V S A H C N L R L P G S S N S P A S A S R I A K T T G A 1600 W S A V A W C L L T A T S A S Q V Q A I L L P Q P P E L L R L Q V 1600 G V Q W H G V C S L Q P P P P R F K Q F S C L S L P N C * D Y R C 1600 | | | | | | | | | CACGCCACTATGCCCGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCATTATATGGACCAGGCTGGTCTCAAACTC CTGACCTCATGATCCACCCA 1700 R H Y A R L I F V F L V E M G F H Y M D Q A G L K L L T S * S T H 1700 H A T M P G * F L Y F * * R W G F I I W T R L V S N S * P H D P P T 1700

T P L C P A N F C I F S R D G V S L Y G P G W S Q T P D L M I H P 1700 | | | | | | | | | CCTCAACCTCCCAAAGTCCTGGGATTACAGGCCACTGCATCGAGACCATCCTGGCTAACACGGTGAAACTCTGTCTCTAC TAAATAAATAAAAAAAATTA 1800 L N L P K S W D Y R P L H R D H P G * H G E T L S L L N K * K K L 1800 S T S Q S P G I T G H C I E T I L A N T V K L C L Y * I N K K N * 1800 P Q P P K V L G L Q A T A S R P S W L T R * N S V S T K * I K K I S 1800 | | | | | | | | | GCCTGGTATGGTGGTGGGCGCCTGCAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTTGAACCCGGGAGGCA GAGCTTGCAGTGAGCCGAGA 1900 A W Y G G G R L Q S Q L L G R L R Q E N G V E P G R Q S L Q * A E I 1900 P G M V V G A C S P S Y S G G * G R R M A L N P G G R A C S E P R 1900 L V W W W A P A V P A T R E A E A G E W R * T R E A E L A V S R D 1900 | | | | | | | | | TCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCGAGACTCTATCTCAAAAAAAAAAAAGAAAAAAATCTTGCCAGCAAT ACTCTGAAAATTAAAATCCT 2000 A P L H S S L G D R A R L Y L K K K K E K N L A S N T L K I K I L 2000 S R H C T P A W A T E R D S I S K K K K K K I L P A I L * K L K S * 2000 R A T A L Q P G R Q S E T L S Q K K K R K K S C Q Q Y S E N * N P 2000 | | | | | | | | | AATCTGATTTTTTTTTTTTTTGAGATGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACT GCAAGCTTCCGCCTCCCGGG 2100 I * F F F F L R W S L A L S P R L E C S G A I S A H C K L P P P G 2100 S D F F F F * D G V S L C H P G W S A V A R S R L T A S F R L P G 2100 N L I F F F F E M E S R S V T Q A G V Q W R D L G S L Q A S A S R V 2100 | | | | | | | | | TTCACGCCATTCTCCTGCCTCAGTCTCCCGAGTAGCTGGGACTACAGGCTCCCGCCACCACACCAGGCTAATTTTTTTTA TATTTTTAGTAGAGACAGGG 2200 F T P F S C L S L P S S W D Y R L P P P H Q A N F F Y I F S R D R V 2200 S R H S P A S V S R V A G T T G S R H H T R L I F F I F L V E T G 2200 H A I L L P Q S P E * L G L Q A P A T T P G * F F L Y F * * R Q G 2200 | | | | | | | | |

TTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATCA CAGGCGTGAGCCACCGCGCC 2300 S P C * P G W S R S P D L V I H P P R P P K V L G S Q A * A T A P 2300 F H H V S Q D G L D L L T S * S T R L G L P K C W D H R R E P P R P 2300 F T M L A R M V S I S * P R D P P A S A S Q S A G I T G V S H R A 2300 | | | | | | | | | CGGCCCCTAATGTGATTTTTAAGCCCAATATTTAGATGATTATGAGCGTTTAAATTATTATTTCAAGAATTATGTTTTGT AGGCAGAGAAAATCCTGAAC 2400 G P * C D F * A Q Y L D D Y E R L N Y Y F K N Y V L * A E K I L N 2400 A P N V I F K P N I * M I M S V * I I I S R I M F C R Q R K S * T 2400 R P L M * F L S P I F R * L * A F K L L F Q E L C F V G R E N P E L 2400 | | | | | | | | | TTTCCCTTTACAGGAACCCGAAAGACGCGAAATTATACTCGAACCGGGCGGCGTGCTACACGAAATTATTAGAATTCCAA TTAGCGTTAAAAGACTGCGA 2500 F P F T G T R K T R N Y T R T G R R A T R N Y * N S N * R * K T A K 2500 F P L Q E P E R R E I I L E P G G V L H E I I R I P I S V K R L R 2500 S L Y R N P K D A K L Y S N R A A C Y T K L L E F Q L A L K D C E 2500 | | | | | | | | | AGAATGCATCCAATTAGAACCGACGTTCATCAAAGGGTACACGCGGAAAGCGGCGGCGTTAGAAGCGATGAAAGACTACA CGAAAGCGATGGACGTGTAC 2600 N A S N * N R R S S K G T R G K R R R * K R * K T T R K R W T C T 2600 R M H P I R T D V H Q R V H A E S G G V R S D E R L H E S D G R V P 2600 E C I Q L E P T F I K G Y T R K A A A L E A M K D Y T K A M D V Y 2600 | | | | | | | | | CAAAAAGCGTTAGACTTAGACTCGTCGTGCAAAGAAGCGGCGGACGGGTACCAACGGTGCATGATGGCGCAATACAACCG GCACGACTCGCCGGAAGACG 2700 K K R * T * T R R A K K R R T G T N G A * W R N T T G T T R R K T 2700 K S V R L R L V V Q R S G G R V P T V H D G A I Q P A R L A G R R 2700 Q K A L D L D S S C K E A A D G Y Q R C M M A Q Y N R H D S P E D V 2700 | | | | | | | | | TGAAACGGCGGGCGATGGCGGACCCGGAAGTGCAACAAATCATGTCGGACCCGGCGATGCGGTTAATCTTAGAACAAATG CAAAAAGACCCGCAAGCGTT 2800 * N G G R W R T R K C N K S C R T R R C G * S * N K C K K T R K R Y 2800 E T A G D G G P G S A T N H V G P G D A V N L R T N A

K R P A S V 2800 K R R A M A D P E V Q Q I M S D P A M R L I L E Q M Q K D P Q A L 2800 | | | | | | | | | ATCGGAACACTTAAAAAACCCGGTGATCGCGCAAAAAATCCAAAAATTAATGGACGTGGGGTTAATCGCGATCCGG 29 00 R N T * K T R * S R K K S K N * W T W G * S R S G 2900 I G T L K K P G D R A K N P K I N G R G V N R D P 2900 S E H L K N P V I A Q K I Q K L M D V G L I A I R 2900