NAME of DRUG (GENERIC NAME/ BRAND NAME) GENERIC NAME: MANNITOL

THERAPEUTIC ACTION

INDICATION

CONTRAINDICATION

ADVERSE EFFECT

NURSING MANAGEMENT

Elevates the osmolarity of the glomerular filtrate, thereby hindering BRAND the reabsorption of NAME: water and leading Osmitrol to a loss of water, sodium, chloride DRUG (used for CLASSES: diagnosis of Diagnostic Agent glomerular Osmotic Diuretic filtration rate); Urinary Irrigant creates an osmotic gradient in the eye PREGNANCY between plasma CATEGORY B and ocular fluids, thereby reducing IOP; creates an DOSAGES: osmotic effect, 100 ml every 4 leading to hours decreased swelling in posttransurethral prostatic resection.

Prevention and treatment of the oliguric phase of renal failure Reduction of intracranial pressure and treatment of cerebral edema; of elevated IOP when the pressure cannot be lowered by other means Promotion of the urinary excretion of toxic substances Diagnostic use: Measurement of GFR Irrigant in

Contraindicated with anuria due to severe renal disease Use cautiously with pulmonary congestion, active intracranial bleeding (except during craniotomy), dehydration, renal disease, heart failure, pregnancy, lactation.

ASSESSMENT: History: Pulmonary CNS: Dizziness, headache, blurred congestion, active intracranial bleeding, vision, seizures dehydration, renal CV: Hypotension, disease, heart failure, pregnancy, lactation hypertension edema, HF, thrombophlebitis, Physical: Skin color, tachycardia, chest lesions, edema, hydration; pain orientation, muscle strength, reflexes, Dermatologic: pupil; pulses, BP, Urticaria, skin perfusion; R, pattern, necrosis with adventitious sounds ; infiltration urinary output patterns; serum GI: Nausea, electrolytes, anorexia, dry urinalysis, renal mouth, thirst function tests GU: Diuresis, TEACHING urine retention POINTS: You may experience Hematologic: these side effects: Fluid and

transurethral prostatic resection or other transurethral procedures.

electrolyte imbalances, hyponatremia Respiratory: Pulmonary congestion, rhinitis

increased urination; GI upset (eat frequent meals); dry mouth (suck sugarless lozenges); headache, blurred vision (use caution when moving, ask for assistance). Report difficulty breathing, pain at the IV site, chest pain.