Professional Documents
Culture Documents
Blood picture ESR (usually elevated high) Liver function (deranged if metastasis) Alkaline phosphatase (if bony origin can be due to increased bone destruction/increased bone turnover) Ca/PO4 (some tumors or metastases can have hypercalcemia) Tumor marker (PSA if metastases from prostate) Serum protein electrophoresis (monoclonal band in myeloma)
05/02/08
Blood count
Hb Ht Leko Trombo 11.2 33 12.900 244.000
35 29 30 0.95 124
Serum electrophoresis
Radiology
Pelvic X-Ray
Soft tissue shadow Bony erosion or pressure effect Calcification
Thorax
Assess for possible metastasis
CT scan
Assess area of destruction by tumor
MRI
Detect skip lesion Extent of bone malignancy Involvement of other bone compartment or neurovascular structure Helps to plan biopsy tract and resection plan
Biopsy
Frozen section
Adequacy and check margins
Closed aspiration
Cheap, no delay, few risk
Open biopsy
More material and absolute hemostasis
Biopsy sacral
Chondrosarcoma a/r sacral