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DWI INDRIA ANGGRAINI

given i.v. or i.m. a useful alternative when -mimetics are contraindicated must be carefully titrated because its nonspecific calcium antagonism leads to blockade of cardiac impulse conduction and of neuromuscular transmission.

Uterine muscle is contracted by PGF2 , TXA2, and low concentrations of PGE2; PGI2 and high concentrations of PGE2 cause relaxation. PGF2 , together with oxytocin, is essential for the onset of parturition.

The effects of prostaglandins on uterine function are discussed below.

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