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Drug Study Final
Drug Study Final
CLASSIFICATION & DOSAGE Threpeutic: diuretics Pharmacologic: loop diuretics DOSAGE: 40mg IV STAT
MECHANISM OF ACTION -Inhibits sodium and chloride reabsorption at the proximal tubules, distal tubules and ascending loop of henle leading to excretion of water together with sodium, chloride and potassium.
SIGNIFICANCE -For the treatment of edema associated with renal disease, including the nephritic syndrome -For the treatment of hypertension alone or in combination with other antihypertensive agents.
NURSING IMPLICATION -Asses fluid status during therapy -Monitor blood pressure and pulse before and during administration -Watch for signs of hypokalemia, such as muscle weakness and cramps -Monitor glucose level in diabetic patients -Advise patient to immediately report ringing in ears, severe abdominal pain, or sore throat and fever, these symptoms may indicate toxicity - Monitor patients blood pressure and pulse rate frequently -Assess for signs of Angioedme -Instruct patient to take drug 1 hour before meals; food in the GI tract may reduce absorption. -Advise to report signs and symptoms of infection, such as fever and sore throat.
-Inhibits ACE, preventing conversion of Angiotensin I to Angiotensin II, a potent vasoconstrictor. Less Abgiotensin II decreses peripheral arterial resistance, decreasing aldosterone secretion, which reduces sodium and water retention and lowers blood pressure -Reduces total acid load in GI tract, elevates gastric pH to reduce pepsin activates, strengthens gastric mucosal barrier, and increase esophageal sphincter tone
-Captopril is used alone or in combination with other drig for the treatment of high blood pressure, it may also slow the progression of kidney failure in patients with diabetes or high blood pressure.
-Used to treat symptoms caused by too much stomach acid such as heartburn, stomach upset or indigestion.
--Watch for evidence of hypercalcemia( nausea, vomiting, headache, confusion and anorexia) -Advise patient not to take calcium carbonate indiscriminately or to switch antacids with prescribed advise. -Tell patient to notify prescriber about signs and symptoms of GI