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CONCLUDING REMARKS
The foregoing review has hopefully shown that the biosynthesis of the ergoline ring system, which at one time looked like a simple sequence of mostly non-specific reactions, involves a substantial number of very specific and rather complicated transformations. It has also
Medicinal Chemistry and Pharmacognosy, particularly Professors J. M. Cassady, C.-j. Chang, P. F. Heinstein and J. E. Robbers, and with a number of other research groups, particularly that of Professor D. Groger, Halle (Saale), to all of whom I am greatly indebted. Finally I want to thank Mrs. Lorraine Smith for her skill and patience in typing this manuscript and drawing all the structures.
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