Schematic Diagram (Book Based) Modifiable Risk Factors Family hx Race Age Prediabetes Gestational DM Non-Modifiable Risk Factors

ctors Weight Inactivity Diet Lifestyle

Decreased insulin sensitivity

Release of stored glucose

Hyperglycemia

Diabetes Mellitus

Peripheral Vascular Disease

Autonomic Neuropathy

Peripheral Neuropathy

Arteriosclerosis

Cholesterol Emboli

Decreased delivery of oxygen nutrients and antibiotics

Decreased flare reaction

Decreased Perspiration

Autosymphatectomy

Sensory

Motor

Dry, cracked skin

Increased blood flow

Loss of sensation

Interosseous atrophy

Hypertension

Decreased oxygen perfusion to the brain Impaired wound healing Fainting

Increased bone reabsorption

Joint collapse

Painless Trauma: Mechanical Chemical Thermal

Cocked-up toes Thinning fat pad over metatarsal head

Deformed foot (Charcot) Major Gangrene New pressure points

Infection Blue toe syndrome Gangrene

ulceration

Amputation