Bacteria invasion of peritoneal cavity causing inflammation of the membrane that lines the abdomen peritoneum (peritonitis)

If not: Septic shock s/sx: 1. Decrease blood pressure 2. decrease blood volume

If treated: Prescribed antibiotic

Coma

Fluid replacement therapy

Death

Recovery

PATHOPHYSIOLOGY
PREDISPOSING FACTORS - Age (11-20y.o.) - Sex (Male) PRECIPITATING FACTORS - Diet (raw foods, guava) - History of appendicitis - Constipation (Fecalithe matter) Obstruction of the appendix by fecalithe (hardened stool), lymph nodes, tumor, and foreign objects

Increased intraluminar pressure inside the appendix that result to distention of appendix

Normal bacteria found in appendix begin to invade (infect) the lining of the wall Inflammatory response body response to the bacterial invasion in the wall of appendix. Increased immune complex (disease plus antibody) causes swelling of tissue resulting to inflammation of appendix.

Inflammation and infection spread through the wall of the appendix causing death of tissue. The appendix ruptures due to increased pressure

Perforation (formation of a hole in an organ), fecal materials exits to peritoneal cavity causing formation of abscess (periappendical abscess). Infection spreads throughout the abdomen (peritoneal cavity)